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Human Polyclonal Glutathione Peroxidase 1 Primary Antibody for IF (p), IHC (p) - ABIN750583
Miyamoto, Tsumuraya, Ohtaki, Dohi, Satoh, Xu, Tanaka, Murai, Watanabe, Sugiyama, Aruga, Shioda: PACAP38 Suppresses Cortical Damage in Mice with Traumatic Brain Injury by Enhancing Antioxidant Activity. in Journal of molecular neuroscience : MN 2014
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Human Polyclonal Glutathione Peroxidase 1 Primary Antibody for ICC, IF - ABIN4314702
Bachmann, Burté, Pramana, Conte, Brown, Orimadegun, Ajetunmobi, Afolabi, Akinkunmi, Omokhodion, Akinbami, Shokunbi, Kampf, Pawitan, Uhlén, Sodeinde, Schwenk, Wahlgren, Fernandez-Reyes, Nilsson: Affinity proteomics reveals elevated muscle proteins in plasma of children with cerebral malaria. in PLoS pathogens 2014
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Human Polyclonal Glutathione Peroxidase 1 Primary Antibody for ICC, IF - ABIN443480
Sun, Zhang, Zhong, Sun, Zhou: Dietary Fisetin Supplementation Protects Against Alcohol-Induced Liver Injury in Mice. in Alcoholism, clinical and experimental research 2016
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Human Polyclonal Glutathione Peroxidase 1 Primary Antibody for IHC (p), IHC - ABIN251496
Kato, Kato, Abe, Matsumura, Nishino, Aoki, Itoyama, Asayama, Awaya, Hirano, Ohama et al.: Redox system expression in the motor neurons in amyotrophic lateral sclerosis (ALS): immunohistochemical studies on sporadic ALS, superoxide dismutase 1 (SOD1)-mutated familial ALS, and SOD1-mutated ... in Acta neuropathologica 2005
Mouse (Murine) Polyclonal Glutathione Peroxidase 1 Primary Antibody for ELISA, WB - ABIN4314700
Lubos, Kelly, Oldebeken, Leopold, Zhang, Loscalzo, Handy: Glutathione peroxidase-1 deficiency augments proinflammatory cytokine-induced redox signaling and human endothelial cell activation. in The Journal of biological chemistry 2011
Studied the importance of selenium in bovine female reproductive function. Gene expression analysis revealed selenoprotein gene GPX1 was significantly up-regulated in large healthy follicles.
did not find any significant inhibition of bovine GPx-1 by (S)- or (R)-misonidazole.
Data indicate mRNA level and activity of GPx1 are regulated by level of selenium supplied to hepatocytes.
homocysteine decreases GPx1 activity by altering the translational mechanism
glutathione peroxidase-1 activity is decreased by aminoglycosides through interference with selenocysteine incorporation
GPx1 plays a key role in blocking the promotion of porcine circovirus type 2 replication
The developmental expression of GPX1 and thioredoxin reductase during fetal development and the effect of maternal selenium consumption on the expression of these proteins are reported.
Notably, CUEDC2 (show CUEDC2 Antibodies) promoted E3 ubiquitin ligases tripartite motif-containing 33 (TRIM33 (show TRIM33 Antibodies))-mediated the antioxidant enzyme, glutathione peroxidase 1 (GPX1) ubiquitination, and proteasome-dependent degradation.
GPx1 does not clearly exacerbate hyperoxia-induced increases in oxidative stress or lung injury but may alter pulmonary immune function.
GPx-1 expression deters the unfolded protein response following exposure to cigarette smoke
Glutathione peroxidase 1 (GPx1) knockdown not only induced oxidative stress characterized by the increased production of reactive oxygen species (ROS (show ROS1 Antibodies)) but also caused reductive stress indicated by an elevation of glutathione (GSH)/oxidized GSH (GSSG) ratio.
Exposure to far infrared rays significantly protects acute restraint stress oxidative burdens via inhibition of JAK2 (show JAK2 Antibodies)/STAT3 (show STAT3 Antibodies) signaling by induction of GPx-1.
Genetic inhibition of Gpx1 potentiates cocaine-induced renal damage via activation of AT1R (show AGTRAP Antibodies) by inhibition of PI3K-Akt (show AKT1 Antibodies) signaling.
Glutathione peroxidase 1 deficiency attenuates concanavalin A-induced liver injury by induction of T-cell hyporesponsiveness through chronic reactive oxygen species exposure.
GPx1 was found to play a critical role in regulating pro-inflammatory pathways in vascular endothelium.
Plasmalogen enrichment via batyl alcohol supplementation attenuated atherosclerosis in ApoE (show APOE Antibodies)- and ApoE (show APOE Antibodies)/GPx1-deficient mice.
Gpx1 expression in the mouse skeletal muscle can be altered by both exercise and dyslipidemia through changes in DNA methylation (show HELLS Antibodies), leading to a fine regulation of free radical metabolism.
No significant differences in allelic or genotypic frequencies of GPX1 rs1050450 or GSTP1 (show GSTP1 Antibodies) rs1695 were detected between Chinese schizophrenia cases and controls.
Genetic variations in selenoprotein genes modulated both GPX1 and SELENOP selenoprotein gene expression and global gene expression in response to Brazil nut supplementation.
Allele-specific interaction between GPX1 and MnSOD (show SOD2 Antibodies) affects the levels of Bcl2 (show BCL2 Antibodies), Sirt3 (show SIRT3 Antibodies) and E-cadherin (show CDH1 Antibodies).
GPX1, GPX3 and GPX4 may be upregulated in response to a change in oxidative stress during an acute coronary syndromes
The Pro198Leu polymorphism (rs1050450) to the selenoprotein glutathione peroxidase 1 gene (GPX1), and GSTM1 (show GSTM1 Antibodies) deletion had no effect on mercury levels in mildly exposed people, suggesting these genetic variants impact mercury levels only in highly exposed populations.
Evaluation of Glutathione Peroxidase and KCNJ11 (show KCNJ11 Antibodies) Gene Polymorphisms in Patients with New Onset Diabetes Mellitus After Renal Transplantation
G/C (rs8179169; Arg5Pro) and T/C (rs4991448; Leu6Pro) polymorphisms significantly associated with vitiligo (show MITF Antibodies)
Data show that the inflammation of the gallbladder wall (IGW) correlated significantly with plasma GPX1 and hs-CRP (show CRP Antibodies) (high-sensitivity C-reactive protein (show CRP Antibodies)) values suggesting that inflammation and oxidative stress are related.
High GPX1 expression is associated with oral squamous cell carcinoma.
GPX1 is a gatekeeper restraining the oncogenic power of mitochondrial ROS (show ROS1 Antibodies) generated by SOD2 (show SOD2 Antibodies) is presented. Review.
This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
glutathione peroxidase Gpx1
, glutathione peroxidase
, cellular glutathione peroxidase
, cytosolic glutathione peroxidase
, putative glutathione peroxidase
, selenium-dependent glutathione peroxidase 1
, glutathione peroxidase 1
, glutathione peroxidase 1 S homeolog