TAB1 Proteins
7 TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) Proteins from 5 manufacturers are available on www.antibodies-online.com.
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TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (AA 1-504) protein (His tag) Protein
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (AA 1-502) protein (His tag) Protein
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (AA 1-504) protein (GST tag) Protein
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (AA 3-100) protein (GST tag) Protein
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (AA 189-439) protein (His tag,T7 tag) Protein
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) Protein Protein
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) protein (Myc-DYKDDDDK Tag) Protein
TAB1 Protein Profile
Protein Summary
The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alternative names and synonyms associated with TAB1
- TGF-beta activated kinase 1 (MAP3K7) binding protein 1 (TAB1) antibody
- TGF-beta activated kinase 1/MAP3K7 binding protein 1 (Tab1) antibody
- 3'-Tab1 antibody
- 2310012M03Rik antibody
- b2b449Clo antibody
- Map3k7ip1 antibody
Protein level used designations for TAB1
TAK1-binding protein 1 , TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 , mitogen-activated protein kinase kinase kinase 7-interacting protein 1 , transforming growth factor beta-activated kinase-binding protein 1 , TGF-beta-activated kinase 1-binding protein 1 , Tak1-binding protein 1 , beta activated kinase-1 binding protein-1 , mitogen activated protein kinase kinase kinase 7 interacting protein 1 , mitogen-activated protein kinase kinase kinase 7 interacting protein 1
GENE ID | SPECIES |
---|---|
10454 | Homo sapiens |
66513 | Mus musculus |
315139 | Rattus norvegicus |
100358246 | Oryctolagus cuniculus |
418014 | Gallus gallus |
481245 | Canis lupus familiaris |
519958 | Bos taurus |
100153785 | Sus scrofa |
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