Protein Summary

This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response.

Alternative names and synonyms associated with TICAM1

• toll like receptor adaptor molecule 1 (TICAM1) antibody
• toll-like receptor adaptor molecule 1 (Ticam1) antibody
• toll-like receptor adaptor molecule 1 (ticam1) antibody

• AW046014 antibody
• AW547018 antibody
• IIAE6 antibody
• MyD88-3 antibody
• PRVTIRB antibody
• Show all synonym aliases
• TICAM-1 antibody
• trif antibody

Protein level used designations for TICAM1

TIR domain containing adaptor inducing interferon-beta , TIR domain-containing adapter molecule 1 , TIR domain-containing adapter protein inducing IFN-beta , proline-rich, vinculin and TIR domain-containing protein B , putative NF-kappa-B-activating protein 502H , toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta , toll-interleukin I receptor domain containing adaptor molecule 1 , toll-like receptor adaptor molecule 1 , TIR domain-containing adapter molecule 1-like , TIR domain-containing adaptor inducing interferon-beta , toll-interleukin 1 receptor domain-containing adapter protein inducing interferon-beta , TICAM-1 , TIR-domain containing adaptor inducing IFN-beta , TRIF/TICAM1