Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Human TLR4 Antibodies:
anti-Mouse (Murine) TLR4 Antibodies:
anti-Rat (Rattus) TLR4 Antibodies:
Go to our pre-filtered search.
Human Monoclonal TLR4 Primary Antibody for ChIP, CyTOF - ABIN252522
Kessel, Toubi, Pavlotzky, Mogilner, Coran, Lurie, Karry, Sukhotnik et al.: Treatment with glutamine is associated with down-regulation of Toll-like receptor-4 and myeloid differentiation factor 88 expression and decrease in intestinal mucosal injury caused by ... in Clinical and experimental immunology 2008
Show all 63 Pubmed References
Dog (Canine) Monoclonal TLR4 Primary Antibody for BP, CyTOF - ABIN4360113
Rallabhandi, Bell, Boukhvalova, Medvedev, Lorenz, Arditi, Hemming, Blanco, Segal, Vogel: Analysis of TLR4 polymorphic variants: new insights into TLR4/MD-2/CD14 stoichiometry, structure, and signaling. in Journal of immunology (Baltimore, Md. : 1950) 2006
Show all 45 Pubmed References
Dog (Canine) Monoclonal TLR4 Primary Antibody for FACS - ABIN252065
Konno, Wakabayashi, Akashi-Takamura, Ishii, Kobayashi, Takahashi, Kusumoto, Saitoh, Yoshizawa, Miyake: A molecule that is associated with Toll-like receptor 4 and regulates its cell surface expression. in Biochemical and biophysical research communications 2005
Show all 24 Pubmed References
Human Monoclonal TLR4 Primary Antibody for BP, CyTOF - ABIN4360167
Degraaf, Zasłona, Bourdonnay, Peters-Golden: Prostaglandin E2 reduces Toll-like receptor 4 expression in alveolar macrophages by inhibition of translation. in American journal of respiratory cell and molecular biology 2014
Show all 24 Pubmed References
Dog (Canine) Monoclonal TLR4 Primary Antibody for FACS - ABIN4360117
Mempel, Voelcker, Köllisch, Plank, Rad, Gerhard, Schnopp, Fraunberger, Walli, Ring, Abeck, Ollert et al.: Toll-like receptor expression in human keratinocytes: nuclear factor kappaB controlled gene activation by Staphylococcus aureus is toll-like receptor 2 but not toll-like receptor 4 or platelet ... in The Journal of investigative dermatology 2003
Show all 23 Pubmed References
Dog (Canine) Monoclonal TLR4 Primary Antibody for BP, CyTOF - ABIN4360119
Basak, Pathak, Bhattacharyya, Mandal, Pathak, Kundu et al.: NF-kappaB- and C/EBPbeta-driven interleukin-1beta gene expression and PAK1-mediated caspase-1 activation play essential roles in interleukin-1beta release from Helicobacter pylori ... in The Journal of biological chemistry 2005
Show all 22 Pubmed References
Dog (Canine) Monoclonal TLR4 Primary Antibody for FACS, ICC - ABIN4360164
Cognasse, Hamzeh, Chavarin, Acquart, Genin, Garraud: Evidence of Toll-like receptor molecules on human platelets. in Immunology and cell biology 2005
Show all 21 Pubmed References
Dog (Canine) Monoclonal TLR4 Primary Antibody for BP, ELISA - ABIN4360158
Scheel, Papavlassopoulos, Blunck, Gebert, Hartung, Zähringer, Seydel, Schromm: Cell activation by ligands of the toll-like receptor and interleukin-1 receptor family depends on the function of the large-conductance potassium channel MaxiK in human macrophages. in Infection and immunity 2006
Show all 18 Pubmed References
Human Monoclonal TLR4 Primary Antibody for FACS - ABIN4360193
Zanoni, Navone, Lunardi, Tridente, Bason, Sivori, Beri, Dolcino, Valletta, Corrocher, Puccetti: In celiac disease, a subset of autoantibodies against transglutaminase binds toll-like receptor 4 and induces activation of monocytes. in PLoS medicine 2006
Show all 16 Pubmed References
Human Monoclonal TLR4 Primary Antibody for FACS - ABIN4360159
Allam, Peng, Appel, Wenghoefer, Niederhagen, Bieber, Bergé, Novak: Toll-like receptor 4 ligation enforces tolerogenic properties of oral mucosal Langerhans cells. in The Journal of allergy and clinical immunology 2008
Show all 15 Pubmed References
Lipopolysaccharides-mediated TLR4 signaling enhances TGF-beta (show TGFB1 Antibodies) response through downregulating BAMBI (show BAMBI Antibodies) during prostatic hyperplasia.
Increased expressions of TLR-3 (show TLR3 Antibodies), TLR-4 and CD80 (show CD80 Antibodies) mRNA and the level of urinary CD80 (show CD80 Antibodies)/creatinine could be useful markers to differentiate patients of steroid-sensitive nephrotic syndrome in relapse from those with steroid-resistant nephrotic syndrome.
These findings suggest that TLR4 methylation may be protective against the damage conferred by alcohol use disorders on precuneus and inferior parietal gray matter
Bronchial epithelial overexpression of TLR4 and NOD1 (show NOD1 Antibodies) in severe/very severe stable COPD (show ARCN1 Antibodies), associated with increased bronchial inflammation and P. aeruginosa bacterial load, may play a role in the pathogenesis of COPD (show ARCN1 Antibodies)
Authors firstly uncovered that TLR4/NFkappaB (show NFKB1 Antibodies) mediated inflammation signaling and miR (show MLXIP Antibodies)-146a participated in ART-related preterm birth patients, which suggests that importance of TLR4/NFkappaB (show NFKB1 Antibodies)/miR (show MLXIP Antibodies)-146a signaling in clinical interventions and biomarkers of ART-related perinatal or neonatal outcomes.
Expression of X-linked Toll-like receptor 4 signaling gene IRAK1 (show IRAK1 Antibodies) was significantly elevated in female neonates vs. male neonates.
Positive rates of iNOS (show NOS2 Antibodies) in cervical tissues were 72.1%, 28.2%, and 3.1% in the -HPV-positive patients with cervical cancer (CC group), HR-HPV group, and controls, respectively (P < 0.05). Levels of TLR3 (show TLR3 Antibodies), TLR4, TLR7 (show TLR7 Antibodies), TLR8 (show TLR8 Antibodies), NF-kappaB (show NFKB1 Antibodies) p65 (show GORASP1 Antibodies), and iNOS (show NOS2 Antibodies) in cervical epithelial cells were higher in CC group than in other groups.
Prolonged hypertension influences peripheral monocyte TLR4 expression and IL-17A (show IL17A Antibodies) serum levels
TLR4-stimulated oral keratinocytes inhibited the proliferation of oral lichen planus CD4 (show CD4 Antibodies)(+) T cells and CD8 (show CD8A Antibodies)(+) T cells, and simultaneously prompted their apoptosis.
Reduced expression of caveolin-1 (show CAV1 Antibodies) in monocytes could aggravate the TLR4-mediated inflammatory cascade
NLRC5 (show NLRC5 Antibodies) knockout mice fed with high fat showed accelerated fibrosis and inflammation response by promoting alpha-SMA (show SMN1 Antibodies), Collagen I, Collagen III, TLR4/MyD88 (show MYD88 Antibodies), phosphorylated IKKalpha (show CHUK Antibodies), IkappaBalpha (show NFKBIA Antibodies) and NF-kappaB (show NFKB1 Antibodies) expression.
a previously unknown mechanism for the development of intestinal injury equivalent to that seen in human Necrotizing enterocolitis and that is not dependent on TLR4 pathways, is reported.
Forsythoside A exerts an anti-endotoxin effect by blocking the LPS/TLR4 signaling pathway and inhibiting Tregs in vitro.
data suggest that S100A8 (show S100A8 Antibodies)/A9 acts directly on BV-2 microglial cells via binding to TLR4 and RAGE (show AGER Antibodies) on the membrane and then stimulates the secretion of proinflammatory cytokines through ERK (show EPHB2 Antibodies) and JNK (show MAPK8 Antibodies)-mediated NF-kappaB (show NFKB1 Antibodies) activity in BV-2 microglial cells.
recombinant NS1, expressed and purified from eukaryotic cells, induces cytokine production via TLR4 but not TLR2/6.
Vitamin K2 can inhibit intimal calcification of aortic artery induced by high-fat diet in ApoE(-/-) mice via suppression of TLR2/4 expression.
Endotoxaemia enhanced early venous thrombosis occurs in a TLR-4 and ICAM-1 (show ICAM1 Antibodies) dependent fashion, and is potentiated by neutropenia.
TLR4-independent lipopolysaccharide uptake is promoted by kukoamine B in hepatocytes
This study provides new molecular insight into the ability of miR (show MLXIP Antibodies)-29a to inhibit TLR2 and TLR4 signaling, which thus slows the progression of cholestatic liver deterioration.
Hyperin inhibited lipopolysaccharide-induced inflammatory response in acute kidney injury by inhibiting TLR4 and NLRP3 (show NLRP3 Antibodies) signaling pathways.
a single nucleotide polymorphism of the bovine toll like receptor 4 gene (TLR4) in New Zealand (NZ) Holstein-Friesian x Jersey (HF x J) cross dairy cows was associated with milk production traits
STA3 (show ARHGEF3 Antibodies) facilitates TLR4-dependent IL-6 (show IL6 Antibodies) and IL-8 (show IL8 Antibodies) production via IL-6 (show IL6 Antibodies) receptor-positive feedback in endometrial cells.
Studied genetic diversity of the Toll-like receptor gene TLR4 in Czech Red and Czech Red Pied cattle. Found 8 SNPs, which were grouped into 18 haplotypes.
TLR4 polymorphisms are associated with lower reproductive Performance.
As a pilot study, the present results revealed that identified SNPs in IL8 (show IL8 Antibodies) and TLR4 genes can be used as a genetic marker and predisposing factor for resistance/susceptibility to digital dermatitis in dairy cows. However, TLR4 gene may be a potential candidate for such disease.
Transcription levels of TLR2, TLR4, and CD14 (show CD14 Antibodies) in Holstein cows with retained placenta significantly decreased between the first and the seventh day postpartum.
Bovine viral diarrhea virus type 2 infection modulates TLR4 responsiveness in differentiated myeloid cells.
TLR2 and TLR4 mediate innate response against Cryptosporidium parvum in bovine intestinal epithelial cells.
TLR4 polymorphisms are associated with susceptibility to Mycobacterium avium ssp. paratuberculosis infection in Holsteins
positive correlation between lower neutrophil apoptosis and higher expression of TLR2 and TLR4 with the formation of NETs and change in surface architecture.
TLR2, 3, 4, and 8 mRNA expression is strongly upregulated and correlates with the progression of atherosclerosis in the aorta. Fluvastatin significantly inhibited this progress and reduced inflammation via TLR downregulation.
The expression of TLR4 protein and mRNA, the level of activated NF-kappaB (show NFKB1 Antibodies) (p65 (show SYT1 Antibodies)) were respectively detected.
Lipopolysaccharide upregulates the expression of rabbit TLR2 and 4 in the uterine body and horn, and the expression of TLR4 in the ovary.
Polydatin might have a protective effect on lung ischemia/reperfusion injury by down-regulating TLR4 and NF-kappaB (show NFKB1 Antibodies) expression, then inhibiting the release of mediators of inflammation as ICAM-1 (show ICAM1 Antibodies).
TLR4 expression is upregulated in the brain after experimental subarachnoid haemorrhage
The elevated expression of TLR4 was detected after SAH (show ACSM3 Antibodies) and peaked on day 3 and 5. TLR4 is increasingly expressed in a parallel time course to the development of cerebral vasospasm in a rabbit experimental model of SAH (show ACSM3 Antibodies).
The TWEAK (show TNFSF12 Antibodies)-independent Fn14 (show TNFRSF12A Antibodies) activation augments TLR4-mediated inflammatory responses in the intestine of piglets.
These results further confirm the involvement of the TLR4 signaling pathway in resistance to E. coli F18 (show MAMLD1 Antibodies) in Meishan weaned piglets.
Data suggest expression of TLR4 and NFKB (nuclear factor kappa B) are regulated by dietary factors affecting innate immunity; here, Lactobacillus acidophilus in feed down-regulates expression of TLR4 and NFKB in mononuclear cells after LPS (show IRF6 Antibodies) challenge.
At 30 days after autotransplantation of a pig kidney, mRNA expression increases for TLR4.
Data suggest TLR2, TLR4, and calcium signaling in enterocytes play principal roles in mucosal immunity against enterotoxigenic Escherichia coli; probiotic Lactobacillus delbrueckii and its extracellular polysaccharides appear to stimulate TLR2/TLR4.
TLR2 is required for the suppression of TLR4 signaling activation.
The current study screened for single nucleotide polymorphisms (SNPs) in the TLR4 gene and tested their association with Salmonella fecal shedding.
The role of TLR2, TLR4 and RP105 (show CD180 Antibodies)/MD1 (show LY86 Antibodies) in the immunoregulatory effect of acidic exopolysaccharides from Lactobacillus plantarum N14 (show CLPTM1 Antibodies), is reported.
Data suggest expression of TLR4 in liver can be regulated by dietary factors; here, supplementation with aspartate down-regulates expression of TLR4 in liver in a model of liver disease.
Fish Oil attenuates the activation of the HPA (show HPSE Antibodies) axis induced by LPS (show IRF6 Antibodies) challenge. So it may be associated with decreasing the production of brain or peripheral proinflammatory cytokines through inhibition of TLR4 and NOD signaling pathways in weaned pigs.
The research findings suggest that Th17 cells are involved in active equine inflammatory bowel disease, and that TLR4 expression was increased in affected horses.
A low steady expression of TLR4, MD-2 (show LY96 Antibodies) and CD14 (show CD14 Antibodies) mRNA was demonstrated for the intestinal samples with no variation between the intestinal segments analysed.
In the present study, the authors show that TLR4 expression is significantly decreased following the exogenous expression of BPV-1 E2 and E7 in primary equine fibroblasts.
evidence that pulmonary intravascular macrophages are equipped with TLR4 to handle and rapidly respond to circulating endotoxins
TLR4/MD-2 (show LY96 Antibodies) complex is responsible for recognition of Rhodococcus spheroides lipopolysaccharide as an agonist in equine cells.
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.
, homolog of Drosophila toll
, lipopolysaccharide response
, Toll-like receptor4 protein
, Toll-like receptor 4-like protein