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TMPRSS2 Products

(Transmembrane Protease, serine 2 (TMPRSS2))

Categories

This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008].

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Featured TMPRSS2 Categories

TMPRSS2 Antibodies

High quality antibodies with extensive validation data.

TMPRSS2 ELISA Kits

Reliable ELISA kits for a wide range of species.

TMPRSS2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TMPRSS2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (6)
Cat. No. ABIN6149286
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7435142
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (4)
Cat. No. ABIN570926
Quantity 100 μg
Datasheet Datasheet

Recommended TMPRSS2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6960140
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962285
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960141
Quantity 96 tests
Datasheet Datasheet

Recommended TMPRSS2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323090
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323092
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3109868
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our TMPRSS2 products

Mache, Schulze, Holland, Bourquain, Gensch, Oh, Nitsche, Dürrwald, Laue, Wolff: "SARS-CoV-2 Omicron variant is attenuated for replication in a polarized human lung epithelial cell model." in: Communications biology, Vol. 5, Issue 1, pp. 1138, (2022) (PubMed).

Lam, Dang, Flynn, Hardt, Schmidt: "TMPRSS2, a novel membrane-anchored mediator in cancer pain." in: Pain, Vol. 156, Issue 5, pp. 923-30, (2015) (PubMed).

Tomlins, Laxman, Dhanasekaran, Helgeson, Cao, Morris, Menon, Jing, Cao, Han, Yu, Wang, Montie, Rubin, Pienta, Roulston, Shah, Varambally, Mehra, Chinnaiyan: "Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer." in: Nature, Vol. 448, Issue 7153, pp. 595-9, (2007) (PubMed).

Synonyms and alternative names related to TMPRSS2

transmembrane protease serine 2-like (LOC100739411), transmembrane protease, serine 2 (TMPRSS2), transmembrane protease, serine 2 (Tmprss2), D16Ertd61e, PP9284, PRSS10

Protein level used designations for TMPRSS2

  • epitheliasin
  • serine protease 10
  • transmembrane protease serine 2
  • plasmic transmembrane protein X
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