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Human IL17RD Protein expressed in HEK-293 Cells - ABIN2723368
Mellett, Atzei, Bergin, Horgan, Floss, Wurst, Callanan, Moynagh: Orphan receptor IL-17RD regulates Toll-like receptor signalling via SEFIR/TIR interactions. in Nature communications 2015
This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin (PMID: 19079364). The gene product also affects fibroblast growth factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling (PMID: 21663947, 18096367).
interleukin 17 receptor D
, interleukin-17 receptor D-like
, IL-17 receptor D
, interleukin-17 receptor D
, interleukin-17 receptor-like protein
, sef homolog
, similar expression to FGF genes protein