NFKB2 ELISA Kits

12 Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) ELISA Kits from 6 manufacturers are available on www.antibodies-online.com.

Data Quality
  • 2
Type
  • 12
    Kit
Target
  • 12
Reactivity
  • 9
  • 8
  • 6
  • 1
Application
  • 12
Method Type
  • 7
  • 4
Analytical Method
  • 7
  • 3
Detection Method
  • 10
  • 2
Plate
  • 7
  • 4
Binding Specificity
  • 2
  • 2
  • 1
Sample
  • 6
  • 3
  • 2
  • 2
  • 2
Suggested next Filters
12 Products
ReactivityHuman
Detection MethodColorimetric, Sandwich ELISA
Detection Range0.31 ng/mL - 20 ng/mL
Order details Cat. No. ABIN417750
$700.00
Plus shipping costs $45.00
Delivery in 13 to 16 Business Days
ReactivityMouse
Detection MethodColorimetric, Sandwich ELISA
Detection Range0.15 ng/mL - 10 ng/mL
Order details Cat. No. ABIN424176
$720.00
Plus shipping costs $45.00
Delivery in 13 to 16 Business Days
ReactivityHuman, Mouse, Rat
Detection MethodColorimetric, Cell ELISA
Detection RangeQualitative
Order details Cat. No. ABIN1381355
$380.00
96 tests
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman, Mouse, Rat
Detection MethodFluorometric, Cell ELISA
Detection RangeQualitative
Order details Cat. No. ABIN5691974
$480.00
2 x 96 tests
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman, Mouse
Detection MethodFluorometric, Cell ELISA
Detection RangeQualitative
Order details Cat. No. ABIN5691975
$480.00
2 x 96 tests
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman, Mouse, Rat
Detection MethodColorimetric, Cell ELISA
Detection RangeQualitative
Order details Cat. No. ABIN1380651
$480.00
2 x 96 tests
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman, Mouse, Rat
Detection MethodColorimetric, Cell ELISA
Detection RangeQualitative
Order details Cat. No. ABIN1380652
$480.00
2 x 96 tests
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman, Mouse
Detection MethodColorimetric, Cell ELISA
Detection RangeQualitative
Order details Cat. No. ABIN1380470
$480.00
2 x 96 tests
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
Uncoated, Samples: Cell Samples, Suspension Cell Culture
ReactivityHuman, Mouse, Rat
Detection MethodColorimetric, Cell ELISA
Detection RangeQualitative
Order details Cat. No. ABIN2685065
ISO
$714.29
1 kit
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
Pre-coated, Samples: Cell Culture Supernatant, Cell Samples, Plasma, Serum, Tissue Lysate
ReactivityHuman
Detection MethodColorimetric, Sandwich ELISA
Detection RangeQuantitative
Order details Cat. No. ABIN6951668
ISO
$734.80
96 tests
Plus shipping costs $45.00
Delivery in 21 to 31 Business Days
ReactivityRat
Detection MethodColorimetric, Sandwich ELISA
Order details Cat. No. ABIN5069337
$795.14
Plus shipping costs $45.00
Delivery in 16 to 21 Business Days
ReactivityChicken
Detection MethodColorimetric,
Order details Cat. No. ABIN1145396
$1,095.60
96 tests
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
  • <
  • 1
  • >

NFKB2 Antigen Profile

Protein Summary

NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF- kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF- kappa-B inhibitor (I-kappa-B) family. In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappa-B complex which translocates to the nucleus. In a non-canonical activation pathway, the MAP3K14- activated CHUK/IKKA homodimer phosphorylates NFKB2/p100 associated with RelB, inducing its proteolytic processing to NFKB2/p52 and the formation of NF-kappa-B RelB-p52 complexes. The NF-kappa-B heterodimeric RelB-p52 complex is a transcriptional activator. The NF-kappa-B p52-p52 homodimer is a transcriptional repressor. NFKB2 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p100 and generation of p52 by a cotranslational processing. The proteasome-mediated process ensures the production of both p52 and p100 and preserves their independent function. p52 binds to the kappa-B consensus sequence 5'-GGRNNYYCC-3', located in the enhancer region of genes involved in immune response and acute phase reactions. p52 and p100 are respectively the minor and major form\; the processing of p100 being relatively poor. Isoform p49 is a subunit of the NF-kappa-B protein complex, which stimulates the HIV enhancer in synergy with p65 (By similarity).

Alternative names and synonyms associated with NFKB2

  • nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 (Nfkb2) antibody
  • lyt antibody
  • NF-kappaB2 antibody
  • p49 antibody
  • p49/p100 antibody
  • p50B antibody
  • p52 antibody

Protein level used designations for NFKB2

DNA-binding factor KBF2 , NF kappaB2 , nuclear factor NF-kappa-B p100 subunit , nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100

GENE ID SPECIES
18034 Mus musculus