Browse our ATP6V1C1 Proteins (ATP6V1C1)

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene is one of two genes that encode the V1 domain C subunit proteins and is found ubiquitously. This C subunit is analogous but not homologous to gamma subunit of F-ATPases. Previously, this gene was designated ATP6D.

• ATPase H+ transporting V1 subunit C1 (ATP6V1C1)
• ATPase, H+ transporting, lysosomal V1 subunit C1 (Atp6v1c1)
• ATPase H+ transporting V1 subunit C1 (Atp6v1c1)
• ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 (atp6v1c1)
• ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 L homeolog (atp6v1c1.L)
• Show all gene names
• ATPase, H+ transporting, lysosomal, V1 subunit C1a (atp6v1c1a)
• ATPase, H+ transporting, lysosomal, V1 subunit C1b (atp6v1c1b)

• 1700025B18Rik protein
• ATP6C protein
• ATP6D protein
• atp6v1c1 protein
• atp6v1c1l protein
• Show all synonym aliases
• ATPase protein
• si:zc215i13.2 protein
• U13839 protein
• vatC protein
• Vma5 protein
• wu:fd12h05 protein
• zgc:92684 protein

H(+)-transporting two-sector ATPase, subunit C , H+ -ATPase C subunit , H+-transporting ATPase chain C, vacuolar , V-ATPase C subunit , V-ATPase subunit C 1 , V-type proton ATPase subunit C 1 , subunit C of vacuolar proton-ATPase V1 domain , vacuolar ATP synthase subunit C , vacuolar proton pump C subunit , vacuolar proton pump subunit C 1 , vacuolar proton pump, 42-kD subunit , vacuolar proton-ATPase, subunit C, VI domain , ATPase, H+ transporting, V1 subunit C , vacuolar H+ -ATPase C subunit , ATPase, H+ transporting, lysosomal V1 subunit C1 , ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 , Vacuolar proton pump subunit C 1 , V-type proton ATPase subunit C 1-like , ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C , ATPase, H+ transporting, lysosomal, V1 subunit C , V-ATPase subunit C 1-A , V-type proton ATPase subunit C 1-A , vacuolar proton pump subunit C 1-A , ATPase, H+ transporting, lysosomal, V1 subunit C, isoform 1, like , V-ATPase subunit C 1-B , V-type proton ATPase subunit C 1-B , vacuolar proton pump subunit C 1-B