Browse our anti-Lactoferrin (LTF) Antibodies

Human Lactotransferrin (LTF) interaction partners

1. VEN-120 (recombinant human lactoferrin) reduced inflammation in murine models of inflammatory bowel disease [IBD], accompanied by increased Tregs in the intestinal lamina propria. Data provide a novel immunological mechanism by which VEN-120 modulates T cells to restrict inflammatory T cell-driven disease.

2. LTF (lactotransferrin/lactoferrin), and ETV7 (Ets variant 7 (show ETV7 Antibodies)) were mainly related with cell apoptosis and immune responses.

3. Recombinant human lactoferrin to affect BCG (show SLC11A1 Antibodies) and LPS (show IRF6 Antibodies) stimulation of CD14thorn and CD16thorn monocyte derived macrophages, leading to modulation of cytokine production post stimulation.

4. CNS disease was associated with enhanced expression of cytoplasmic and membranous ITGA10 and nuclear PTEN (P < 0.0005, P = 0.002, P = 0.024, respectively). sCNSL presented decreased membranous CD44 (show CD44 Antibodies) and nuclear and cytoplasmic cadherin-11 expressions (P = 0.001, P = 0.006, P = 0.048, respectively). In PCNSL lactoferrin expression was upregulated (P < 0.0005).

5. High plasma LTF expression is associated with Insulin (show INS Antibodies) Resistance.

6. Lactoferrin is a nonheme iron-binding glycoprotein strongly expressed in human and bovine milk and it plays many functions during infancy such as iron homeostasis and defense against microorganisms. [Review]

7. Faecal biomarkers lactoferrin, calprotectin (show S100A8 Antibodies), and PMN-elastase (show ELANE Antibodies) were able to distinguish between ulcerative colitis patients with mucosal healing from clinical remission and mild disease, showed significant correlations with endoscopy, and were predictive of a flare.

8. Review of the many ways lactoferrin influences the complex immune machinery and the known and putative mechanisms that may explain its properties.

9. Review of the role of lactoferrin in gastrointestinal and immune development and function. Preclinical findings support clinical studies demonstrating benefits of dietary lactoferrin in the prevention of infections, late onset sepsis, and necrotizing enterocolitis.

10. This review discusses the current state of knowledge of lactoferrin as a conditional nutrient for neurodevelopment, neuroprotection, and cognitive function during the period of rapid brain growth.

Cow (Bovine) Lactotransferrin (LTF) interaction partners

1. Retinoic acid enhanced TbetaRIII expression and that this increase contributed to LF-stimulated IgA (show IgA Antibodies) production.

2. lactoferrin and glutamate receptor-interacting protein 1 (show GRIP1 Antibodies) showed a twofold increase during the controlled internal drug release -induced estrous stage compared to the levels in non-estrous stage in bovine cervical mucus

3. Review of preclinical studies in piglets fed bovine lactoferrin demonstrating the role of lactoferrin in gastrointestinal and immune development and function.

4. Review of preclinical studies in piglets fed bovine lactoferrin demonstrating the role of lactoferrin in neurodevelopment and cognition.

5. Bovine lactoferrin SNPs -270T>C and -156A>G showed close linkage disequilibrium (r(2)=0.76). The SNP -190G>A showed a significant association with SCS (show TWIST1 Antibodies), and individuals with genotype GG had higher SCS (show TWIST1 Antibodies) than genotypes AG and AA.

6. Lf upregulated several canonical signaling pathways associated with neurodevelopment and cognition and influenced ~10 genes involved in the brain-derived neurotrophin (show BDNF Antibodies) factor (BDNF (show BDNF Antibodies)) signaling pathway.

7. Results from this study indicated the probable role played by Lactoferrin promoter to serve as candidate gene for mastitis susceptibility among indigenous and crossbred milch cattle.

8. Supplementation with lactoferrin (1,600 mg/kg per day) effectively suppressed the increase in transepidermal water loss, reduction in skin hydration, aberrant epidermal hyperplasia, and cell apoptosis induced by UV irradiation.

9. Bovine Lf can capture and terminate the cycle of ROS (show ROS1 Antibodies) production by heme iron. Luminal iron binding properties of Lf might assist in regulating excess levels of stored iron and down-regulate ferritin (show FTL Antibodies) production and associated pro-inflammatory signaling.

10. The results showed potent stimulation of the proliferative response of PBMC by bovine lactoferrin, associated with the induction of proinflammatory cytokines only in the case of colostral bovine lactoferrin.

Mouse (Murine) Lactotransferrin (LTF) interaction partners

1. Data indicate that lactoferrin uptake across duodenum by glyceraldehyde-3-phosphate dehydrogenase (GAPDH (show GAPDH Antibodies)).

2. Results show that LTF gene expression is downregulated in colorectal cancer tumors and its knock out in mouse model of colitis-associated colorectal dysplasia suggests its protective role in colorectal mucosal immunity and inflammation.

3. Data show that the expression of several genes encoding salivary antimicrobial proteins, such as secretory leukocyte peptidase inhibitor (SLPI (show SLPI Antibodies)), S100A8 (show S100A8 Antibodies), and lactotransferrin, was reduced due to myeloid differentiation dactor 88 (MyD88 (show MYD88 Antibodies)) deficiency.

4. Lactoferrin dampens high-fructose corn syrup-induced hepatic manifestations of the metabolic syndrome in a murine model.

5. We conclude that lactotransferrin represents a late stage differentiation marker of neutrophils, macrophages and distinct subtypes of dendritic cells.

6. The variations in lactoferrin expression levels during developmental stages may be related to its regulatory role in mouse mammary gland immunity.

7. the present work indicated that LF stimulated MC3T3-E1 preosteoblast differentiation mainly through LRP1 (show LRP1 Antibodies)-independent PKA and p38 (show CRK Antibodies) signaling pathways.

8. Studie indicate that in iCre knock-in line, the iCre is expressed from endogenous lactoferrin (Ltf) promoter.

9. administration of lactoferrin led to autopotentiated increased expression of the LTF gene. The decreased lactoferrin mRNA levels in association with obesity and diabetes were replicated in mice adipose tissue

10. The up-regulation of lactorferrin in the brains of the transgenic mouse model of Alzheimer's disease provides evidence of an important role for lactoferrin in alzheimer disease-affected brain tissues

Horse (Equine) Lactotransferrin (LTF) interaction partners

1. lactoferrin was found in the cytoplasm of principal cells in the corpus and cauda of the epididymis in peri (show PLIN1 Antibodies)- and post-pubertal, but not pre-pubertal stallions. Further, lactoferrin binds to sperm, suggesting a role for protection or regulation of sperm.

2. These data indicate that clinically normal skin of horses affected by CHS (show LYST Antibodies) is not characterized by modified maintenance levels of lactoferrin mRNA.

Pig (Porcine) Lactotransferrin (LTF) interaction partners

1. this paper shows that recombinant lactoferrin peptide LF-6 produced with intein technology has both antibacterial and immunomodulatory activity in mice

2. We propose that lactoferrin functions in the immune defense of the small intestinal mucosa by targeting the population of T cells in the lamina propria

3. Involvement of HSP27 (show HSPB1 Antibodies) and lactoferrin in porcine endometrium and neutrophils activity.

4. Growth performance of animal pups is enhanced by directly feeding the genetically engineered milk containing enriched pLF protein in transgenic mice.