Browse our anti-SLC30A4 (SLC30A4) Antibodies

Human Solute Carrier Family 30 (Zinc Transporter), Member 4 (SLC30A4) interaction partners

1. There was a significant increase in protein levels of ZnT4 in the prefrontal cortex in Major depression disorder, relative to control subjects.

2. TRPML1 works in concert with ZnT4 to regulate zinc translocation between the cytoplasm and lysosomes.

3. The loss of ZnT4 in airway inflammation contributes to airway epithelium vulnerability in diseases such as asthma.

4. our results suggest that alterations in Zn transport proteins ZnT-1, ZnT-4 and ZnT-6 may contribute to the pathology observed in preclinical Alzheimer's disease subjects before onset of clinical symptoms

5. Genomic localization, organization; exclusion in variants of acrodermatitis enteropathica.

6. not responsible for acrodermatitis enteropathica in Japanese families

7. hZnT4 is constitutively expressed in the human breast and may be one of the several members of the ZnT family involved in the transport of zinc into milk

8. The hZnT4 protein did not co-localise with intracellular free zinc pools, suggesting that hZnT4 is not involved in transport of zinc into vesicles destined for secretion into milk.

9. decreased intensity of ZnT4 immunoreactivity occurred in the progression from benign to invasive localized prostate cancer and to metastatic disease

10. Decreased hZnT-4 expression is associated with prostate tissue abnormalities independent of total cellular zinc content.

11. findings implicate a role for ZnT(4) in mast cell Zn homeostasis and suggest that granule pools of Zn may be distinct from those regulating activation of procaspase-3 and NF-kappaB.

12. Our results show that Zn transporter-4 and Zn transporter-6 are significantly (P<0.05) increased in hippocampus/parahippocampal gyrus of early Alzheimer's disease and Alzheimer's disease subjects.

13. hZnT-4 is found in the plasma membrane. It is most highly expressed in Molt-4 cells, up-regulated after treatment with phytohemagglutinin & is responsible for the measured decrease of intracellular zinc content after high zinc exposure.

14. Data show that ZNT4 is extensively present in the Abeta-positive plaques in the cortex of human AD brains.

Mouse (Murine) Solute Carrier Family 30 (Zinc Transporter), Member 4 (SLC30A4) interaction partners

1. Loss of ZnT4 has profound consequences on mammary epithelial cell secretion and may promote tissue remodeling in the mammary gland during early lactation.

2. It was shown that that ZnT4 transports Zn into the trans-Golgi network, which is critical for key secretory functions of the mammary cell.

3. Expression of zinc transporter ZnT4 in mouse choroid epithelial cells suggests that the choroid plexus plays an important role in regulation of zinc homeostasis in the brain.