Browse our anti-Podocalyxin-Like (PODXL) Antibodies

Full name:: anti-Podocalyxin-Like Antibodies (PODXL)

On www.antibodies-online.com are 413 Podocalyxin-Like (PODXL) Antibodies from 28 different suppliers available. Additionally we are shipping Podocalyxin-Like Kits (62) and Podocalyxin-Like Proteins (27) and many more products for this protein. A total of 512 Podocalyxin-Like products are currently listed.

Synonyms:: AW121214, cPCLP1, fc18d02, Gp135, Gp200, Ly102, MEP21, PC, PCLP, PCLP-1, PCLP1, podocalyxin, Podxl, wu:fc18d02

list all antibodies	Gene Name	GeneID	UniProt
	PODXL	5420	O00592
	PODXL	27205	Q9R0M4
	PODXL	192181	Q9WTQ2
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Relevant Pathways for anti-Podocalyxin-Like Antibodies

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Top referenced anti-Podocalyxin-Like Antibodies

Mouse (Murine) Polyclonal PODXL Primary Antibody for CyTOF, FACS - ABIN4899592 : Kumagai, Baldwin, Aoudjit, Nezvitsky, Robins, Jiang, Takano: Protein tyrosine phosphatase 1B inhibition protects against podocyte injury and proteinuria. in The American journal of pathology 2014 (PubMed)
Show all 13 Pubmed References
Human Monoclonal PODXL Primary Antibody for ICC, FACS - ABIN151343 : Badcock, Pigott, Goepel, Andrews: The human embryonal carcinoma marker antigen TRA-1-60 is a sialylated keratan sulfate proteoglycan. in Cancer research 1999 (PubMed)
Show all 7 Pubmed References
Human Polyclonal PODXL Primary Antibody for ICC, IF - ABIN4346616 : Cheung, Davis, Lee, Pang, Nagrani, Rennert, Chan: Methylation of an intronic region regulates miR-199a in testicular tumor malignancy. in Oncogene 2011 (PubMed)
Show all 7 Pubmed References
Human Monoclonal PODXL Primary Antibody for ICC, FACS - ABIN152150 : Matin, Walsh, Gokhale, Draper, Bahrami, Morton, Moore, Andrews: Specific knockdown of Oct4 and beta2-microglobulin expression by RNA interference in human embryonic stem cells and embryonic carcinoma cells. in Stem cells (Dayton, Ohio) 2004 (PubMed)
Show all 6 Pubmed References
Human Monoclonal PODXL Primary Antibody for CyTOF, FACS - ABIN4899748 : Ronconi, Sagrinati, Angelotti, Lazzeri, Mazzinghi, Ballerini, Parente, Becherucci, Gacci, Carini, Maggi, Serio, Vannelli, Lasagni, Romagnani, Romagnani: Regeneration of glomerular podocytes by human renal progenitors. in Journal of the American Society of Nephrology : JASN 2009 (PubMed)
Show all 6 Pubmed References
Human Monoclonal PODXL Primary Antibody for FACS, ICC - ABIN4346634 : Schopperle, Kershaw, DeWolf: Human embryonal carcinoma tumor antigen, Gp200/GCTM-2, is podocalyxin. in Biochemical and biophysical research communications 2002 (PubMed)
Show all 5 Pubmed References
Human Polyclonal PODXL Primary Antibody for CyTOF, FACS - ABIN4899749 : Ylöstalo, Bazhanov, Prockop: Reversible commitment to differentiation by human multipotent stromal cells in single-cell-derived colonies. in Experimental hematology 2008 (PubMed)
Show all 4 Pubmed References
Human Monoclonal PODXL Primary Antibody for CyTOF, FACS - ABIN5503174 : Kim, Kim, Jung, Kim, Kwon, Son, Jang, Choi, Park, Park, Han, Lee, Cho, Bae: Comparative proteomic analysis of human somatic cells, induced pluripotent stem cells, and embryonic stem cells. in Stem cells and development 2012 (PubMed)
Show all 3 Pubmed References
Mouse (Murine) Monoclonal PODXL Primary Antibody for CyTOF, FACS - ABIN4899591 : Maltby, Hughes, Zbytnuik, Paulson, McNagny: Podocalyxin selectively marks erythroid-committed progenitors during anemic stress but is dispensable for efficient recovery. in Experimental hematology 2008 (PubMed)
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Polyclonal PODXL Primary Antibody for WB - ABIN540336 : Kelley, Huntsman, McNagny, Roskelley, Hsi: Podocalyxin: a marker of blasts in acute leukemia. in American journal of clinical pathology 2005 (PubMed)
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More Antibodies against Podocalyxin-Like Interaction Partners

Human Podocalyxin-Like (PODXL) interaction partners

This set of symptoms strikingly mimics previously reported mouse Podxl(-/-) embryos, emphasizing the essential function of PODXL in mammalian kidney development and highlighting this patient as a human PODXL-null model.
These results indicate that PcMab-47 is useful in detecting podocalyxin of oral cancers for immunohistochemical analysis
expression of PODXL associates with TAZ (show TAZ Antibodies) downstream gene expression. Suppression of PODXL induces phosphorylation of LATS1 (show LATS1 Antibodies) and TAZ (show TAZ Antibodies), and is accompanied with a decrease in TAZ (show TAZ Antibodies) protein expression. We speculate that changes in actin cytoskeleton may participate in PODXL-mediated TAZ (show TAZ Antibodies) signaling.
Results show that PODXL performs as a tumor promoter in gastric tumor cells (GC). PODXL is a target gene of miR (show MLXIP Antibodies)-509-3-5P; the ectopic expression of miR (show MLXIP Antibodies)-509-3-5P in GC cell lines inhibits the colony, motility and invasion abilities via negatively targeting PODXL.
Podocalyxin as a major pluripotent marker and novel keratan sulfate proteoglycan (show LUM Antibodies) in human embryonic and induced pluripotent stem cells.
A novel frameshift mutation in PODXL seems to be the likely cause of ARJP in this family.
These findings suggest a potential functional link in colorectal cancer between PODXL, EGFR (show EGFR Antibodies) and BRAF (show BRAF Antibodies).
PODXL enhances motility and invasiveness through an increase in gelsolin-actin interactions in cell protrusions.
Results identify an anti-metastatic miRNA, miR (show MLXIP Antibodies)-5100, that decreases the metastatic ability of pancreatic cancer partially by suppressing expression of PODXL.
Results indicate that urinary podocalyxin is not only an early marker but also a treatment target for diabetic nephropathy (DN).

Mouse (Murine) Podocalyxin-Like (PODXL) interaction partners

Podocalyxin-like protein 1 is a relevant marker for human c-kit (show KIT Antibodies)(pos) cardiac stem cells.(
Podxl-KO led to heightened G-CSF (show CSF3 Antibodies) activation of Rap1a (show RAP1A Antibodies)(GTP (show AK3 Antibodies)), and Rap1a (show RAP1A Antibodies)(GTP (show AK3 Antibodies)) inhibition attenuated Podxl-KO neutrophil migration. Studies have revealed novel roles for Podxl as an important modulator of neutrophil and monocyte formation and of Rap1a (show RAP1A Antibodies) activation during stress hematopoiesis.
Podxl-overexpression in neural stem/progenitor cells leads to an up-regulation of Annexin A2 (show ANXA2 Antibodies).
when endogenous podocalyxin was removed from highly metastatic 4T1 mammary tumor cells there was a decrease in collective invasion . Podocalyxin is a tumor cell-intrinsic regulator of experimental collective tumor cell invasion and tumor budding.
Podocalyxin has a role in glioblastoma multiforme cell invasion and proliferation via beta-catenin (show CTNNB1 Antibodies) signaling
Loss of podocalyxin from the lung vasculature results in changes to the lung structure and function including increased lung volume when inflated under constant pressure (25 cm H2O) and changes to the matrix composition.
CTGF is an important mediator of high glucose-induced podocyte damage and decreases the protein level of podocalyxin by the ERK1/2 pathway.
platelet Podxl is involved in the control of hemostasis acting as a platelet co-stimulator, likely due to its pro-adhesive properties
Full-length recombinant murine podocalyxin recruits NHERF-1 (show SLC9A3R1 Antibodies) to the apical domain. Ectopic expression in human & canine epithelial cells leads to microvilli formation on an apical domain extending laterally to the junctional complexes.
Podocalyxin plays multiple roles in neural development

Podocalyxin-Like (PODXL) Antigen Profile

Antigen Summary

This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.

Alternative names and synonyms associated with Podocalyxin-Like (PODXL)

podocalyxin like (PODXL) antibody
podocalyxin-like (Podxl) antibody
podocalyxin-like (podxl) antibody
podocalyxin like (Podxl) antibody

AW121214 antibody
cPCLP1 antibody
fc18d02 antibody
Gp135 antibody
Gp200 antibody
Ly102 antibody
MEP21 antibody
PC antibody
PCLP antibody
PCLP-1 antibody
PCLP1 antibody
podocalyxin antibody
Podxl antibody
wu:fc18d02 antibody

Protein level used designations for PODXL

GCTM-2 antigen , podocalyxin , podocalyxin-like protein 1 , thrombomucin , podocalyxin-like , PC-like protein 1 , Podocalyxin-like protein 1 , podocalyxin-like protein 1-like

GENE ID	SPECIES
5420	Homo sapiens
27205	Mus musculus
192181	Rattus norvegicus
395755	Gallus gallus
472604	Pan troglodytes
482252	Canis lupus familiaris
563365	Danio rerio
616366	Bos taurus
100462597	Pongo abelii
100512201	Sus scrofa
100727578	Cavia porcellus
100009552	Oryctolagus cuniculus
101106679	Ovis aries

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Show all anti-Podocalyxin-Like (PODXL) Antibodies with Pubmed References

Human Podocalyxin-Like (PODXL) interaction partners

Mouse (Murine) Podocalyxin-Like (PODXL) interaction partners

Antigen Summary

Alternative names and synonyms associated with Podocalyxin-Like (PODXL)

Protein level used designations for PODXL