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POLB Antibodies

(Polymerase (DNA Directed), beta (POLB))
The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of this gene exist, but the full-length nature of only one has been described to date. [provided by RefSeq, Sep 2011].
POLB antibody  (AA 1-335) POLB antibody  (AA 1-335) POLB antibody (AA 1-335) (ABIN3022385)

POLB Reactivity: Human IF, IHC, WB Host: Rabbit Polyclonal unconjugated

POLB antibody  (C-Term) POLB antibody  (C-Term) POLB antibody (C-Term) (ABIN6264332)

POLB Reactivity: Human, Mouse, Rat ELISA, ICC, IF, IHC, WB Host: Rabbit Polyclonal unconjugated

POLB antibody  (AA 1-335) POLB antibody  (AA 1-335) POLB antibody (AA 1-335) (ABIN1327635)

POLB Reactivity: Human IF, IHC (p), WB Host: Mouse Polyclonal unconjugated

POLB Antibodies by Reactivity

Find POLB Antibodies for a variety of species such as anti-Human POLB, anti-Mouse POLB, anti-Rat POLB. The species listed below are among those available. Click on a link to go to the corresponding products.

POLB Antibodies by Application

Find POLB Antibodies validated for a specific application such as WB, IHC, ELISA, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

POLB Antibodies by Host

Find POLB Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

POLB Antibodies by Binding Specificity

Find POLB Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

POLB Antibodies by Clonality

Find available monoclonal or polyclonal POLB Antibodies. Click on a link to go to the corresponding products.

POLB Antibodies by Clone

Find POLB Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

POLB Antibodies by Conjugate

Find POLB Antibodies with a specific conjugate such as Biotin, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular POLB Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IF, IHC, WB
Validations
  • (1)
  • (6)
Cat. No. ABIN3022385
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, ICC, IF, IHC, WB
Validations
  • (4)
Cat. No. ABIN6264332
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF, IHC (p), WB
Validations
  • (4)
Cat. No. ABIN1327635
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, WB
Validations
  • (3)
Cat. No. ABIN7150223
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (2)
  • (2)
Cat. No. ABIN964928
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC, WB
Validations
  • (3)
Cat. No. ABIN7269456
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, WB
Validations
  • (2)
Cat. No. ABIN7184824
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application ELISA, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
  • (2)
Cat. No. ABIN1386139
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC, WB
Validations
  • (2)
Cat. No. ABIN3184326
Quantity 100 μL
Datasheet Datasheet
Reactivity Chicken, Cow, Human, Mouse, Rat
Application IHC, WB
Validations
  • (2)
Cat. No. ABIN7296630
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, ELISA, WB
Validations
  • (2)
Cat. No. ABIN1533255
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (9)
Cat. No. ABIN966876
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (9)
Cat. No. ABIN966879
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (9)
Cat. No. ABIN966878
Quantity 0.1 mg
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN6741696
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our POLB Antibodies

Sykora, Kanno, Akbari, Kulikowicz, Baptiste, Leandro, Lu, Tian, May, Becker, Croteau, Wilson, Sobol, Yasui, Bohr: "DNA polymerase beta participates in mitochondrial DNA repair." in: Molecular and cellular biology, (2017) (PubMed).

Dutto, Sukhanova, Tillhon, Cazzalini, Stivala, Scovassi, Lavrik, Prosperi: "p21CDKN1A Regulates the Binding of Poly(ADP-Ribose) Polymerase-1 to DNA Repair Intermediates." in: PLoS ONE, Vol. 11, Issue 1, pp. e0146031, (2016) (PubMed).

Preet, Siddharth, Satapathy, Das, Nayak, Das, Wyatt, Kundu: "Chk1 inhibitor synergizes quinacrine mediated apoptosis in breast cancer cells by compromising the base excision repair cascade." in: Biochemical pharmacology, Vol. 105, pp. 23-33, (2016) (PubMed).

Siddharth, Nayak, Nayak, Das, Kundu: "ABT-888 and quinacrine induced apoptosis in metastatic breast cancer stem cells by inhibiting base excision repair via adenomatous polyposis coli." in: DNA repair, Vol. 45, pp. 44-55, (2016) (PubMed).

Xu, Zhang, Zhang, Meng, Zhang, Jiang, Xu, Van Meter, Seluanov, Gorbunova, Mao: "SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner." in: Cell cycle (Georgetown, Tex.), Vol. 14, Issue 2, pp. 269-76, (2015) (PubMed).

Quiñones, Thapar, Yu, Fang, Sobol, Demple: "Enzyme mechanism-based, oxidative DNA-protein cross-links formed with DNA polymerase β in vivo." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 28, pp. 8602-7, (2015) (PubMed).

Swain, Rao: "Age-dependent decline of DNA base excision repair activity in rat cortical neurons." in: Mechanisms of ageing and development, Vol. 133, Issue 4, pp. 186-94, (2012) (PubMed).

Huang, Qu, Zhang, Venderova, Haque, Rousseaux, Slack, Woulfe, Park: "The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death." in: Nature cell biology, Vol. 12, Issue 6, pp. 563-71, (2010) (PubMed).

Asagoshi, Liu, Masaoka, Lan, Prasad, Horton, Brown, Wang, Bdour, Sobol, Taylor, Yasui, Wilson: "DNA polymerase beta-dependent long patch base excision repair in living cells." in: DNA repair, Vol. 9, Issue 2, pp. 109-19, (2010) (PubMed).

Iwatsuki, Mimori, Yokobori, Tanaka, Tahara, Inoue, Baba, Mori: "A platinum agent resistance gene, POLB, is a prognostic indicator in colorectal cancer." in: Journal of surgical oncology, Vol. 100, Issue 3, pp. 261-6, (2009) (PubMed).

Aliases for POLB Antibodies

polymerase (DNA directed), beta (polb) Antibodies
DNA polymerase beta (POLB) Antibodies
DNA polymerase X family protein (polB) Antibodies
polymerase (DNA directed), beta S homeolog (polb.S) Antibodies
polymerase (DNA directed), beta (Polb) Antibodies
DNA polymerase beta (Polb) Antibodies
A430088C08Rik Antibodies
DDBDRAFT_0186152 Antibodies
DDBDRAFT_0215784 Antibodies
DDBDRAFT_0232376 Antibodies
DDB_0186152 Antibodies
DDB_0215784 Antibodies
DDB_0232376 Antibodies
POLB Antibodies
wu:fa97a05 Antibodies
zgc:109924 Antibodies
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