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Browse our PFDN5 Proteins (PFDN5)

Full name:: Prefoldin Subunit 5 Proteins (PFDN5)

On www.antibodies-online.com are 11 Prefoldin Subunit 5 (PFDN5) Proteins from 6 different suppliers available. Additionally we are shipping PFDN5 Antibodies (93) and PFDN5 Kits (16) and many more products for this protein. A total of 121 PFDN5 products are currently listed.

Synonyms:: 1190001O17Rik, 1700010A06Rik, D15Ertd697e, Eig1, MM-1, MM1, PFD5, pfdn5, wu:fa09c11, wu:fb38c05, zgc:100894

list all proteins	Gene Name	GeneID	UniProt
	PFDN5	5204	Q99471
	PFDN5	56612	Q9WU28
Rat PFDN5	PFDN5	300257
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PFDN5 Proteins (PFDN5) by Origin

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Relevant Pathways for PFDN5 Proteins

Unfolded protein response

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Human Prefoldin Subunit 5 (PFDN5) interaction partners

Physical interaction of p73 with c-Myc and MM1, a c-Myc-binding protein, and modulation of the p73 function.
Results from a study on gene expression variability markers in early-stage human embryos shows that PFDN5 is a putative expression variability marker for the 3-day, 8-cell embryo stage.
knockdown of PFD2 and PFD5 disrupted prefoldin formation in HTT-expressing cells, resulting in accumulation of aggregates of a pathogenic form of HTT and in induction of cell death.
Rabring7 stimulates c-Myc degradation via mono-ubiquitination of MM-1
MM-1alpha, MM-1gamma, and MM-1gamma, but not MM-1beta, were found to repress transcription activity of c-Myc
Wnt4 gene, a member of the Wnt-beta-catenin pathway, was identified as a target gene of MM-1.
MM-1, a c-Myc interacting protein, interacts with HCV ARFP/F protein, which can result in the enhancement of the c-Myc activity.

Mouse (Murine) Prefoldin Subunit 5 (PFDN5) interaction partners

a genetic disruption in the murine Pfdn5 gene, a subunit of prefoldin, causes a syndrome characterized by photoreceptor degeneration, central nervous system abnormalities, and male infertility
MM-1 may play a role in liver development and growth.

PFDN5 Protein Profile

Protein Summary

This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described.

Alternative names and synonyms associated with PFDN5

prefoldin subunit 5 (PFDN5)
prefoldin 5 (Pfdn5)
prefoldin subunit 5 (Pfdn5)
prefoldin 5 (pfdn5)
prefoldin subunit 5 (ANI_1_408074)
prefoldin subunit 5 (pfdn5)
prefoldin subunit 5 S homeolog (pfdn5.S)

1190001O17Rik protein
1700010A06Rik protein
D15Ertd697e protein
Eig1 protein
MM-1 protein
MM1 protein
PFD5 protein
pfdn5 protein
wu:fa09c11 protein
wu:fb38c05 protein
zgc:100894 protein

Protein level used designations for Prefoldin Subunit 5 Proteins (PFDN5)

c-myc binding protein , myc modulator-1 , C-myc-binding protein Mm-1 , EIG-1 , c-myc binding protein MM-1 , myc modulator 1 , prefoldin subunit 5 , prefoldin 5 , Prefoldin subunit 5 , prefoldin subunit 5 S homeolog

GENE ID	SPECIES
5204	Homo sapiens
56612	Mus musculus
282848	Bos taurus
300257	Rattus norvegicus
568182	Danio rerio
4982597	Aspergillus niger CBS 513.88
100195781	Salmo salar
100529026	Ictalurus punctatus
100172545	Pongo abelii
101105486	Ovis aries
494823	Xenopus laevis
100732970	Cavia porcellus
100356360	Oryctolagus cuniculus
607260	Canis lupus familiaris
100859376	Gallus gallus

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