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Human TOMM20 Protein expressed in Wheat germ - ABIN1323332
Zhou, Huang, Shao, May, Prou, Perier, Dauer, Schon, Przedborski: The kinase domain of mitochondrial PINK1 faces the cytoplasm. in Proceedings of the National Academy of Sciences of the United States of America 2008
TOMM20 and MCT1 were highly expressed in diffuse large B-cell lymphoma lymphocytes, indicating an OXPHOS phenotype, whereas non-neoplastic lymphocytes in the control samples did not express these markers.
TOMM20, MCT1, and MCT4 expression was significantly different in Hodgkin and Reed Sternberg (HRS) cells. HRS have high expression of TOMM20, while tumor associated macrophages have absent TOMM20 expression. Tumor-infiltrating lymphocytes have low TOMM20 expression. Reactive lymph nodes in contrast to cHL tumors had low TOMM20, MCT1, and MCT4 expression in lymphocytes and macrophages.
Gsk3beta and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease
TOMM20 protein is highly expressed in both anaplastic thyroid cancer and papillary thyroid cancer compared to non-cancerous thyroid tissue.
Tom20 was ubiquitously distributed in the organ of Corti, allowing well-delineated visualization of inner and outer hair cells. In the inner ear of aged subjects with Meniere's disease, there was decreased expression of Tom20.
a novel model in which Tom20 binds Tom70 to facilitate preprotein release from the chaperones by competition
Tom34 unlike Tom20 does not interact with the leader sequences of mitochondrial precursor proteins
the cytosolic domains of Tom20 and Tom22 function to maintain their substrate preproteins unfolded and prevent them from aggregating on the mitochondrial surface
Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore (By similarity).
translocase of outer mitochondrial membrane 20 homolog a
, translocase of outer mitochondrial membrane 20 homolog (yeast)
, mitochondrial 20 kDa outer membrane protein
, mitochondrial import receptor subunit TOM20 homolog
, outer mitochondrial membrane receptor Tom20
, translocase of outer mitochondrial membrane 20 homolog type II
, outer mitochondrial membrane receptor rTOM20
, Mitochondrial outer membrane receptor TOM20 (MAS20P,S cervisiae homolog) acidic calcium-independent phospholipase A2