Browse our anti-FZD6 (FZD6) Antibodies

Human Frizzled Family Receptor 6 (FZD6) interaction partners

1. Study reports a novel pathogenic variant of the FZD6 gene in autosomal recessive nonsyndromic congenital nail (show CD244 Antibodies) disorder in consanguineous Iranian family.

2. In this paper we report 3 further families with mutations in FZD6 causing Isolated recessive nail (show CD244 Antibodies) dysplasia.

3. monomeric rather than dimeric form is active signal initiating unit of the receptor complex; constitutive signaling to ERK1/2 can be affected by modulating the dimeric status

4. the FZD6-fibronectin actin axis identified in our study could be exploited for drug development in highly metastatic forms of breast cancer

5. we found that FZD6 expression was negatively regulated by miR199a5p

6. The rs3808553 of FZD6 is obviously associated with neural tube defects in Han population of northern China

7. This study confirms our speculation that down-regulation of FZD6 by beta-Carotene is causally related to the observed up-regulation of cancer related genes

8. DVL is a master regulator of FZD6/G-protein signaling

9. FZD6 should be screened for pachyonychia congenita as it is a candidate gene for hereditary nail (show CD244 Antibodies) dysplasias.

10. sequence analysis revealed a novel homozygous missense mutation (c.1266G>A; p.Gly422Asp) located in the transmembrane domain of the protein FZD6 in individuals of a consanguineous family exhibiting features of nail (show CD244 Antibodies) dysplasia

Mouse (Murine) Frizzled Family Receptor 6 (FZD6) interaction partners

1. Fzd4 (show FZD4 Antibodies) and Fzd6 genes have a deep patterning effect on arterial vessel morphogenesis that may determine its functional efficiency

2. Eliminating Fz6 in most hair follicle cells or in the inter-follicular epidermis at E15.5 suggests that planar cell polarity signaling in developing follicles is not required to maintain their orientation.

3. Data show that Wnt receptor, Frizzled-6 (Fzd6) -/- hematopoietic stem/progenitor cell (HSPC (show PSMA7 Antibodies)) exhibit poor emergency hematopoiesis.

4. Fz3 (show FZD3 Antibodies) and Fz6 have partly interchangeable roles in tissue polarity signaling for epithelial orientation and axon growth and guidance

5. This study confirms our speculation that down-regulation of FZD6 by beta-Carotene is causally related to the observed up-regulation of cancer related genes

6. Fzd6-mediated Wnt (show WNT2 Antibodies) signaling likely regulates the overall differentiation process of nail (show CD244 Antibodies)/claw formation.

7. Our results support a role of miR (show MLXIP Antibodies)-194 in liver tumorigenesis through its endogenous target Fzd6.

8. FZD6 mutations can result in severe defects in nail (show CD244 Antibodies) and claw formation through reduced or abolished membranous FZD(6) levels and several nonfunctional WNT (show WNT2 Antibodies)-FZD pathways.

9. The time course of local hair follicle refinement and the resulting evolution of a montage of competing patterns in Fz6(-/-) skin, is defined.

10. Downregulated by dietary beta-carotene in lungs of knockout Bcmo1 (show BCMO1 Antibodies)-deficient mice.