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FZR1 Antibodies

(Fizzy/cell Division Cycle 20 Related 1 (FZR1))
Key regulator of ligase activity of the anaphase promoting complex/cyclosome (APC/C), which confers substrate specificity upon the complex. Associates with the APC/C in late mitosis, in replacement of CDC20, and activates the APC/C during anaphase and telophase. The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely. At the G1/S transition FZR1 is phosphorylated, leading to its dissociation from the APC/C. Following DNA damage, it is required for the G2 DNA damage leads to the ubiquitination of PLK1, preventing entry into mitosis (By similarity).
FZR1 antibody  (N-Term) FZR1 antibody  (N-Term) FZR1 antibody (N-Term) (ABIN2784494)

FZR1 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated

FZR1 antibody  (AA 1-493) FZR1 antibody  (AA 1-493) FZR1 antibody (AA 1-493) (ABIN526652)

FZR1 Reactivity: Human IHC (p), PLA, ELISA, WB Host: Mouse Monoclonal 4C4 unconjugated

FZR1 antibody  (AA 141-240) FZR1 antibody  (AA 141-240) FZR1 antibody (AA 141-240) (ABIN1714172)

FZR1 Reactivity: Human, Mouse ELISA, ICC, IF (cc), IF (p), IHC (fro), IHC (p), WB Host: Rabbit Polyclonal unconjugated

FZR1 Antibodies by Reactivity

Find FZR1 Antibodies for a variety of species such as anti-Human FZR1, anti-Mouse FZR1, anti-Rat FZR1. The species listed below are among those available. Click on a link to go to the corresponding products.

FZR1 Antibodies by Application

Find FZR1 Antibodies validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

FZR1 Antibodies by Host

Find FZR1 Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

FZR1 Antibodies by Binding Specificity

Find FZR1 Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

FZR1 Antibodies by Clonality

Find available monoclonal or polyclonal FZR1 Antibodies. Click on a link to go to the corresponding products.

FZR1 Antibodies by Clone

Find FZR1 Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

FZR1 Antibodies by Conjugate

Find FZR1 Antibodies with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular FZR1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (3)
Cat. No. ABIN526653
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, WB
Validations
  • (2)
Cat. No. ABIN7152956
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (2)
Cat. No. ABIN2773984
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IP, WB
Validations
  • (2)
Cat. No. ABIN487309
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application IHC (p), ELISA, WB
Validations
  • (2)
Cat. No. ABIN1723855
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (1)
Cat. No. ABIN928538
Quantity 100 μL
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN6744910
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Human, Monkey, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6746327
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7152957
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN7152958
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7152959
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application IF
Validations
Cat. No. ABIN7261500
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IP, WB
Validations
Cat. No. ABIN5700882
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ICC, IF, IHC, WB
Validations
Cat. No. ABIN7094244
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN1539455
Quantity 400 μL
Datasheet Datasheet

Latest Publications for our FZR1 Antibodies

Li, Zhang, Yao, Zhang, Wan, Zhang: "APC-Cdh1 Regulates Neuronal Apoptosis Through Modulating Glycolysis and Pentose-Phosphate Pathway After Oxygen-Glucose Deprivation and Reperfusion." in: Cellular and molecular neurobiology, Vol. 39, Issue 1, pp. 123-135, (2019) (PubMed).

Kim, Cho, Wang, Park, Ma, Kim, Gan, Jho, Cha, Jeung, Zhang, Gao, Wei, Jiang, Chung, Yang: "Hippo signaling is intrinsically regulated during cell cycle progression by APC/CCdh1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 116, Issue 19, pp. 9423-9432, (2019) (PubMed).

Yang, Jin, Fan, Liang, Jia, Tan, Huang, Li, Ma, Li: "Inhibition of neddylation causes meiotic arrest in mouse oocyte." in: Cell cycle (Georgetown, Tex.), Vol. 18, Issue 11, pp. 1254-1267, (2019) (PubMed).

Giráldez, Galindo-Moreno, Limón-Mortés, Rivas, Herrero-Ruiz, Mora-Santos, Sáez, Japón, Tortolero, Romero: "G1/S phase progression is regulated by PLK1 degradation through the CDK1/βTrCP axis." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 31, Issue 7, pp. 2925-2936, (2017) (PubMed).

Fuchsberger, Martínez-Bellver, Giraldo, Teruel-Martí, Lloret, Viña: "Aβ Induces Excitotoxicity Mediated by APC/C-Cdh1 Depletion That Can Be Prevented by Glutaminase Inhibition Promoting Neuronal Survival." in: Scientific reports, Vol. 6, pp. 31158, (2016) (PubMed).

Hu, Li, Li, Tan, Wan, Zhu, Zhang, Zhang, Yao: "Downregulation of Cdh1 signalling in spinal dorsal horn contributes to the maintenance of mechanical allodynia after nerve injury in rats." in: Molecular pain, Vol. 12, (2016) (PubMed).

Yamamoto, Takano, Ishiwata, Ohmura, Nagahata, Matsuura, Kamata, Sakamoto, Nakanishi, Kubo, Hishiki, Suematsu: "Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway." in: Nature communications, Vol. 5, pp. 3480, (2014) (PubMed).

Aliases for FZR1 Antibodies

fizzy and cell division cycle 20 related 1 (Fzr1) Antibodies
fizzy/cell division cycle 20 related 1 (CDH1-C) Antibodies
fizzy and cell division cycle 20 related 1 (FZR1) Antibodies
fizzy-related protein homolog (LOC100027495) Antibodies
fizzy-related protein homolog (LOC100179951) Antibodies
fizzy/cell division cycle 20 related 1 (Drosophila) (Fzr1) Antibodies
fizzy/cell division cycle 20 related 1a (fzr1a) Antibodies
AW108046 Antibodies
CDC20C Antibodies
CDH1 Antibodies
Cdh1 Antibodies
CDH1-C Antibodies
FYR Antibodies
Fyr Antibodies
FZR Antibodies
fzr1 Antibodies
FZR2 Antibodies
HCDH Antibodies
HCDH1 Antibodies
zgc:55450 Antibodies
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