FZD6 ELISA Kits

Protein Summary

This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.

Alternative names and synonyms associated with FZD6

• frizzled class receptor 6 (fzd6) antibody
• frizzled class receptor 6 S homeolog (fzd6.S) antibody
• frizzled class receptor 6 (FZD6) antibody
• frizzled class receptor 6 (Fzd6) antibody

• Frizzled-6 antibody
• frizzled6 antibody
• frz6 antibody
• FZ-6 antibody
• Fz6 antibody
• Show all synonym aliases
• HFZ6 antibody
• NDNC10 antibody
• Xfrz6 antibody
• zgc:65879 antibody
• zgc:77440 antibody

Protein level used designations for FZD6

frizzled-6 , frizzled homolog 6 , frizzled 6 , frizzled 6, seven transmembrane spanning receptor , seven transmembrane helix receptor , fz-6 , involved in Wnt signaling, encoding a Wnt receptor , mFz6