Protein Summary

This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with LEF1

• lymphoid enhancer binding factor 1 (LEF1) antibody
• lymphoid enhancer binding factor 1 (lef1) antibody
• lymphoid enhancer-binding factor 1 (lef1) antibody
• lymphoid enhancer binding factor 1 (Lef1) antibody
• lymphoid enhancer factor XLEF-1B (lef1) antibody

• 3000002B05 antibody
• AI451430 antibody
• LEF-1 antibody
• LEF1 antibody
• TCF1ALPHA antibody
• Show all synonym aliases
• TCF7L3 antibody
• TCF10 antibody

Protein level used designations for LEF1

lymphoid enhancer binding factor-1 , lymphoid enhancer-binding factor 1 , lymphoid enhancer-binding factor 1-like , etID310027.1 , LEF-1 , lymphoid enhancer binding factor 1 short isoform , T cell-specific transcription factor 1-alpha , TCF1-alpha , lymphiod enhancer binding factor 1 , transcription factor LEF-1 , lymphoid enhancer binding factor 1