Browse our Phospholipase C beta 1 Proteins (PLCB1)

Full name:: phospholipase C, beta 1 (phosphoinositide-Specific) Proteins (PLCB1)

On www.antibodies-online.com are 7 phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1) Proteins from 5 different suppliers available. Additionally we are shipping Phospholipase C beta 1 Antibodies (55) and Phospholipase C beta 1 Kits (21) and many more products for this protein. A total of 88 Phospholipase C beta 1 products are currently listed.

Synonyms:: 3110043I21Rik, AI132408, EIEE12, mKIAA0581, Phosphb, PI-PLC, PLC'1, PLC-154, PLC-I, PLC154, Plcb, PLCB1, PLCB1A, PLCB1B, PLCbeta1, RATPHOSPHB

list all proteins	Gene Name	GeneID	UniProt
	PLCB1	18795	Q9Z1B3
	PLCB1	23236	Q9NQ66
Rat PLCB1	PLCB1	24654	P10687
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Mouse (Murine) phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1) interaction partners

Data show that phospholipase C (PLC (show PLC Proteins))-beta1 (PLC (show HSPG2 Proteins)-beta1) overexpression determines an increase in beta-catenin (show CTNNB1 Proteins) translocation and that PLC (show HSPG2 Proteins)-beta1, inositol polyphosphate multikinase (IPMK (show IPMK Proteins)) and beta-catenin (show CTNNB1 Proteins) are mediators of the same signaling pathway.
Plcb1 plays a crucial role in the initiation of the genetic program responsible for muscle differentiation and osteogenesis. (Review)
Unpredictable chronic mild stress mice exhibited lower nucleus accumbens (NAC) shell levels of phospholipase Cbeta.
Heightened PLCbeta1b activity observed in diseased myocardium contributes to pathology by PKCalpha (show PKCa Proteins)-mediated contractile dysfunction.
inhibition of miR (show MLXIP Proteins)-214 in C2C12 cells significantly enhances the protein level of PLCbeta1 and promotes C2C12 BMP-2 (show BMP2 Proteins)-induced osteogenesis by targeting PLCbeta1
Results indicate that PLC (show HSPG2 Proteins)-beta1 signalling in the medial prefrontal cortex is required for working memory
In pro-B-lymphoblastic cells (Ba/F3), treated with H2O2, PI-PLCbeta1b conferred resistance to cell death, promoting cell cycle progression and cell proliferation and influencing the expression of cyclin A (show CCNA2 Proteins) and E.
Tnis study demonistrated that plc (show HSPG2 Proteins) beta1 distribuate in mice cerebellum.
Galphaq (show GNAQ Proteins)-coupled Lpar1 (show LPAR1 Proteins) regulates cell proliferation and migration by activating two distinct PLC (show HSPG2 Proteins)-beta isozymes, PLC (show HSPG2 Proteins)-beta1 and PLC (show HSPG2 Proteins)-beta2, respectively.
These findings highlight a novel pathway by which nuclear PLCs affect insulin (show INS Proteins) secretion and identify PPARgamma (show PPARG Proteins) as a novel molecular target of nuclear PLCs.

Human phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1) interaction partners

Dysregulation of primary PLC (show HSPG2 Proteins) signaling is linked to several brain disorders including epilepsy, schizophrenia, bipolar disorder, Huntington's disease, depression and Alzheimer's disease. (Review)
Phospholipase C beta connects G protein signaling with RNA interference. (Review)
The role of PLCb1 nuclear isoform is being analyzed in relation to the cell cycle regulation, the cell differentiation, and different physiopathological pathways focusing on the importance of the nuclear localization from both molecular and clinical point of view. (Review)
Polymorphism of the PLCB4 (show PLCb4 Proteins)/B1 genes might be involved in the coronary artery aneurysm pathogenesis of Kawasaki disease.
Reduction in plasma membrane PI(4,5)P2 abundance by PTPRN2 and PLCbeta1 releases the PI(4,5)P2-binding protein cofilin from its inactive membrane-associated state into the cytoplasm where it mediates actin turnover dynamics.
The rs6108160 polymorphism in the PLCB1 gene reached statistical significance after antidepressant drug use.
results show that PI-PLCbeta1 quantification in MDS (show PAFAH1B1 Proteins) predicts the response to azacitidine and is associated with an increased myeloid differentiation.
one specific Egr-1 (show EGR1 Proteins) binding site was identified at nt-451/-419 and PLCB1 promoter activity was increased more than 5-fold
Cholesterol regulates HERG (show KCNH2 Proteins) K+ channel (show KCNC4 Proteins) activation by increasing phospholipase C beta1 expression
Our data indicate that the amplification of PLCb1a expression, following treatment with kinamycin F, confers a real advantage to K562 cells viability and protects cells themselves from apoptosis.

Phospholipase C beta 1 (PLCB1) Protein Profile

Protein Summary

The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Phospholipase C beta 1 (PLCB1)

phospholipase C beta 1 (PLCB1)
phospholipase C beta 1 S homeolog (plcb1.S)
phospholipase C, beta 1 (Plcb1)
phospholipase C beta 1 (Plcb1)

3110043I21Rik protein
AI132408 protein
EIEE12 protein
mKIAA0581 protein
Phosphb protein
PI-PLC protein
PLC'1 protein
PLC-154 protein
PLC-I protein
PLC154 protein
Plcb protein
PLCB1 protein
PLCB1A protein
PLCB1B protein
PLCbeta1 protein
RATPHOSPHB protein

Protein level used designations for PLCB1

, , , , , , , , , , , , , , , , , , phosphoinositide-specific phospholipase C beta 1 phospholipase C, beta 1 (phosphoinositide-specific) 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1-like 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1 PLC-154 PLC-beta-1 phosphoinositide phospholipase C phosphoinositide phospholipase C-beta-1 phospholipase C-beta-1 phospholipase C-beta-1a 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase monophosphatidylinositol phosphodiesterase phosphoinositidase C phospholipase C-I triphosphoinositide phosphodiesterase PLC-I Phospholipase C-beta1

GENE ID	SPECIES
469875	Pan troglodytes
485773	Canis lupus familiaris
733258	Xenopus laevis
100409716	Callithrix jacchus
100434502	Pongo abelii
100481755	Ailuropoda melanoleuca
100597115	Nomascus leucogenys
18795	Mus musculus
23236	Homo sapiens
24654	Rattus norvegicus
287026	Bos taurus
100152679	Sus scrofa
427687	Gallus gallus
100730572	Cavia porcellus

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