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The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene.
phosphoinositide-specific phospholipase C beta 1
, phospholipase C, beta 1 (phosphoinositide-specific)
, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1-like
, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1
, phosphoinositide phospholipase C
, phosphoinositide phospholipase C-beta-1
, phospholipase C-beta-1
, phospholipase C-beta-1a
, monophosphatidylinositol phosphodiesterase
, phosphoinositidase C
, phospholipase C-I
, triphosphoinositide phosphodiesterase
, Phospholipase C-beta1