Browse our PYGO1 Proteins (PYGO1)

Full name:: Pygopus Homolog 1 (Drosophila) Proteins (PYGO1)

On www.antibodies-online.com are 6 Pygopus Homolog 1 (Drosophila) (PYGO1) Proteins from 4 different suppliers available. Additionally we are shipping PYGO1 Antibodies (46) and many more products for this protein. A total of 58 PYGO1 products are currently listed.

Synonyms:: 2600014C22Rik, zgc:172214

list all proteins	Gene Name	GeneID	UniProt
	PYGO1	72135	Q9D0P5
Rat PYGO1	PYGO1	691857
	PYGO1	26108	Q9Y3Y4
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PYGO1 Proteins (PYGO1) by Origin

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Relevant Pathways for PYGO1 Proteins

WNT Signaling

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More Proteins for PYGO1 Interaction Partners

Mouse (Murine) Pygopus Homolog 1 (Drosophila) (PYGO1) interaction partners

Transcriptional cofactors Bcl9 (show BCL9 Proteins), Bcl9l (show BCL9L Proteins) and Pygo1/2 act independently of beta-catenin (show CTNNB1 Proteins) to ensure proper enamel formation.
even in the absence of the potentially redundant Pygo1, Pygo2 (show PYGO2 Proteins) does not require the H3K4me2/3 binding activity to sustain its function during mouse development
In mammals, the Pygo1/Pygo2 (show PYGO2 Proteins) genes are not absolutely required for canonical Wnt (show WNT2 Proteins) signaling in most developing systems, but rather function as quantitative transducers, or modulators, of Wnt (show WNT2 Proteins) signal intensity
These results suggest that the Pygopus1 plant homeodomain (PHD (show PDC Proteins)) dimerization is functionally important for Lgs/Bcl9 (show BCL9 Proteins) recognition as well as for the regulation of the Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling pathway.

Human Pygopus Homolog 1 (Drosophila) (PYGO1) interaction partners

Data show that human and Drosophila Pygo PHD (show PDC Proteins) fingers associate with their cognate HD1 (show HDAC1 Proteins) domains from BCL9/Legless (show BCL9 Proteins) to bind specifically to the histone H3 (show HIST3H3 Proteins) tail methylated at lysine 4 (H3K4me).

PYGO1 Protein Profile

Protein Summary

Involved in signal transduction through the Wnt pathway (By similarity).

Alternative names and synonyms associated with PYGO1

pygopus 1 (Pygo1)
pygopus family PHD finger 1 (Pygo1)
pygopus family PHD finger 1 (pygo1)
pygopus family PHD finger 1 (PYGO1)

2600014C22Rik protein
zgc:172214 protein

Protein level used designations for PYGO1

pygopus homolog 1 , pygopus 1 , pygopus-like protein 1

GENE ID	SPECIES
72135	Mus musculus
691857	Rattus norvegicus
797729	Danio rerio
415408	Gallus gallus
26108	Homo sapiens

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