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anti-Mouse (Murine) WNT3A Antibodies:
anti-Human WNT3A Antibodies:
anti-Rat (Rattus) WNT3A Antibodies:
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Human Polyclonal WNT3A Primary Antibody for IF (p), IHC (p) - ABIN733178
Gao, Yang, Gao, Xu, Niu, Li, Wen: Salvianolic acid B improves bone marrow-derived mesenchymal stem cell differentiation into alveolar epithelial cells type I via Wnt signaling. in Molecular medicine reports 2015
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Cow (Bovine) Polyclonal WNT3A Primary Antibody for IHC, WB - ABIN2787841
Chiquet, Blanton, Burt, Ma, Stal, Mulliken, Hecht: Variation in WNT genes is associated with non-syndromic cleft lip with or without cleft palate. in Human molecular genetics 2008
Human Polyclonal WNT3A Primary Antibody for IHC (p), ELISA - ABIN2477144
Skalská: [Use of linear logistic regression in classification of observations]. in Sborník v?deckých prací Léka?ské fakulty Karlovy univerzity v Hradci Králové. Supplementum 1991
Show all 2 Pubmed References
Human Polyclonal WNT3A Primary Antibody for ELISA, WB - ABIN2477145
Lai, Cheng, Cheng, Feasel, Beste, Peng, Nusrat, Moreno: SOX4 interacts with plakoglobin in a Wnt3a-dependent manner in prostate cancer cells. in BMC cell biology 2011
Show all 2 Pubmed References
Human Monoclonal WNT3A Primary Antibody for ELISA, ICC - ABIN449669
Denysenko, Annovazzi, Cassoni, Melcarne, Mellai, Schiffer: WNT/β-catenin Signaling Pathway and Downstream Modulators in Low- and High-grade Glioma. in Cancer genomics & proteomics 2015
This work provides a new link between Wnt3a and macrophage-mediated angiogenesis under glucose and oxygen deprivation in vitro.
Wnt (show WNT2 Antibodies) signaling regulates airway epithelial stem cells in adult murine submucosal glands.
Lrp6 (show LRP6 Antibodies) is the key mediator of Wnt3a signaling in osteoblasts and Lrp5 (show LRP5 Antibodies) played a less significant role in mediating Wnt3a signaling.
These data define the mechanism responsible for the repressive effects of nitric oxide (NO) on the transcriptional activity of beta-catenin (show CTNNB1 Antibodies) and link eNOS (show NOS3 Antibodies)-derived NO to the modulation by VEGF (show VEGFA Antibodies) of Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies)-induced endothelial cell proliferation.
These results indicate that PEDF (show SERPINF1 Antibodies) counters Wnt (show WNT2 Antibodies) signaling to allow for osteoblast differentiation and provides a mechanistic insight into how the PEDF (show SERPINF1 Antibodies) null state results in OI type VI.
These results suggest novel mechanisms for Wnt3a-induced osteoblast proliferation and cell survival via Npnt (show NPNT Antibodies) gene expression
this study shows that the Wnt3a expression levels in dendritic cells influences the generation of memory T cells after 5 days in co-culture with naive T cells through activation of the Wnt (show WNT2 Antibodies) canonical pathway
Wnt3a induces Osx (show SP7 Antibodies) expression via p38 MAPK (show MAPK14 Antibodies) signaling in dental follicle cells. Wnt3a-induced Osx (show SP7 Antibodies) expression was inhibited in the presence of p38 mitogen-activated protein kinase (show MAPK14 Antibodies) (MAPK (show MAPK1 Antibodies)) inhibitors (SB203580 and SB202190) at gene and protein levels, as assessed by real-time PCR and immunocytohistochemistry, respectively.
Furthermore, pigment epithelium-derived factor (PEDF (show SERPINF1 Antibodies)), a secreted glycoprotein known for its anti-tumor properties, blocked Wnt3a-directed induction of autophagy proteins. Autophagy inhibition was complemented by reciprocal regulation of the oxidative stress enzymes, superoxide dismutase 2 (SOD2 (show SOD2 Antibodies)) and catalase (show CAT Antibodies).
Ginkgo biloba exocarp extract inhibits tumor angiogenesis, which may be closely relevant to its effect in blockage of Wnt (show WNT2 Antibodies) /beta-catenin (show CTNNB1 Antibodies)-VEGF (show VEGFA Antibodies) signaling pathway in Lewis lung carcinoma.
Wnt3A regulates the expression of 1,136 genes, of which 662 are upregulated and 474 are downregulated in CCD (show RUNX2 Antibodies)-18Co cells. A set of genes encoding inhibitors of the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) pathway stand out among those induced by Wnt3A, which suggests that there is a feedback inhibitory mechanism.
we detected two potential associations with well-recognized skin cancer risk traits that modify miRNA-mRNA interactions: rs2325814 in the 3'UTR (show UTS2R Antibodies) of the MLPH (show MLPH Antibodies) gene and rs752107 in the 3'UTR (show UTS2R Antibodies) of the WNT3A gene.
PCR and western blot results showed that inhibiting the secretion of Wnt3A blocked the Wnt (show WNT2 Antibodies) signaling pathway and prevented Nrf2 (show GABPA Antibodies) signaling. Notably, the Wnt (show WNT2 Antibodies) inhibitor may serve as a radiosensitizing drug
Study found that Wnt3a highly expressed in hepatocellular carcinoma (HCC (show FAM126A Antibodies)) tissues, and confirmed that Wnt3a plays an essential role in HCC (show FAM126A Antibodies) progression. Activation of the Wnt3a pathway is accompanied by higher expression of Notch3 (show NOTCH3 Antibodies). Furthermore, Wnt3a may be critical for HCC (show FAM126A Antibodies) cell cycle and metastasis by regulating cell cycle regulatory proteins and the MAPK (show MAPK1 Antibodies) pathway.
WNT3A supports early stages such as the ALP (show ALP Antibodies) activity, but it does neither improve later stages of the osteogenic differentiation nor it inhibits the genuine adipogenic differentiation of adipose tissue derived mesenchymal stem cells.
SP5 (show SP5 Antibodies) negatively regulates WNT3a transcriptional programs in human pluripotent stem cells.
Suggest that GPC5 (show GPC5 Antibodies) is able to suppress the lung adenocarcinoma metastasis by competitively binding to Wnt3a and inactivating the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling pathway.
WNT3A/beta-catenin (show CTNNB1 Antibodies) signaling inhibition is involved in leflunomide-mediated cytotoxic effects on renal carcinoma (show TSC2 Antibodies) cells
BRG1 (show SMARCA4 Antibodies) may contribute to colon cancer progression through upregulating WNT3A expression.
Here we describe a one-step immobilization technique to covalently bind WNT3A proteins as a basal surface with easy storage and long-lasting activity. We show that this platform is able to maintain adult and embryonic stem cells while also being adaptable for 3D systems
Data suggest that Wnt3, Wnt3a, and Wnt8a (show WNT8A Antibodies) bind to their respective receptors (Fz8 (show FZD2 Antibodies), Lrp6 (show LRP5 Antibodies), and Lypd6 (show LYPD6 Antibodies)) in ordered plasma membrane environments; ordered plasma membrane environments appear to be essential for binding of Wnt (show WNT2 Antibodies) proteins to their receptor complexes and stimulation of downstream signaling activity.
It was shown that Wnt3a-Wnt8a (show WNT8A Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling directly regulates ciliogenic transcription factor foxj1a expression and ciliogenesis in zebrafish Kupffer's vesicle.
In zebrafish embryos lacking Wnt3a, Wnt1 (show WNT1 Antibodies) and Wnt10b (show WNT10B Antibodies), the expression of engrailed orthologs, pax2a and fgf8 (show FGF8 Antibodies) is not maintained after mid-somitogenesis
data suggest a specific role for Wnt3a in the development of cardiac NCCs; propose that this function of wnt3a in r6 is partially mediated by crip2 (show CRIP2 Antibodies) expression in the premigratory cardiac NCCs, which subsequently affects cardiac function and PA patterning
Sulf1 (show SULF1 Antibodies) does not affect Wnt3a-mediated activation of canonical Wnt (show WNT2 Antibodies) signaling.
Wnt3a protein alone is sufficient to rescue the severe loss of inner ear structures resulting from dorsal but not ventral half ablations.
hindbrain-repressive Wnt3a/Meis3/Tsh1 circuit promotes neuronal differentiation and coordinates tissue maturation
Wnt3a thus acts downstream of FAK (show PTK2 Antibodies) to balance anterior-posterior cell fate specification in the developing neural plate
Data suggest a new model for neural anteroposterior patterning, in which Wnt3a from the paraxial mesoderm induces posterior cell fates via direct activation of a crucial transcription factor in the overlying neural plate.
Wnt3A secretion from tectal cells along with ephrin-B1 (show EFNB1 Antibodies) signaling are specifically responsible for enhanced neural responses in the developing optic tectum.
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 96% amino acid identity to mouse Wnt3A protein, and 84% to human WNT3 protein, another WNT gene product. This gene is clustered with WNT14 gene, another family member, in chromosome 1q42 region.
wingless-type MMTV integration site family, member 3A
, protein Wnt-3a-like
, protein Wnt-3a
, vestigial tail
, wingless-type MMTV integration site family, member 3 like
, wnt3 like
, wingless-type MMTV integration site family, member 3
, Wnt-3a homolog
, Wnt3a variant 3
, wingless-type MMTV integration site family member 3a
, wingless-related MMTV integration site 3A