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anti-Mouse (Murine) WNT7A Antibodies:
anti-Human WNT7A Antibodies:
anti-Rat (Rattus) WNT7A Antibodies:
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Human Polyclonal WNT7A Primary Antibody for IHC, IHC (p) - ABIN4366196
Yoshioka, King, Ran, Okuda, MacLean, McAsey, Sugino, Brard, Watabe, Hayashi: WNT7A regulates tumor growth and progression in ovarian cancer through the WNT/β-catenin pathway. in Molecular cancer research : MCR 2012
Show all 4 Pubmed References
Wnt7a has a role in postmenstrual regeneration and proliferation of endometrial glands and luminal epithelium in primates
Wnt7a induces a unique phenotype of monocyte-derived macrophages with lower phagocytic capacity and differential expression of pro- and anti-inflammatory cytokines
experiments indicate that Reck (show RECK Antibodies) and Gpr124 (show GPR124 Antibodies) are part of the cell surface protein (show CD28 Antibodies) complex that transduces Wnt7a- and Wnt7b (show WNT7B Antibodies)-specific signals in mammalian CNS epithelial cells to promote angiogenesis and regulate the BBB (show ALMS1 Antibodies)
WNT7a is sufficient to restore post-pubertal endometrial gland formation.
we found that post-ejaculated semen from fertile wild-type males was solidified and the sperm were entrapped in Wnt7aCre/+;Esr1f/f uteri, compared to the watery semen (liquefied) found in Esr1f/f controls.Kallikrein-related peptidases 3 (KLK3 (show PSA Antibodies)) and other kallikrein (show KLK1 Antibodies)-related peptidases from male prostate glands are responsible for semen liquefaction by cleaving gel-forming proteins
Data show that the WIF domain of Wnt Inhibitory Factor 1 (WIF1 (show WIF1 Antibodies)) is bound by C-terminal domains of Wnt (show WNT2 Antibodies) proteins Wnt5a (show WNT5A Antibodies) and Wnt7a at two sites.
Wnt7a is a novel regulator of ventral midbrain neurogenesis and dopaminergic neuron axon growth and guidance.
Truncated Wnt7a lacking the conserved palmitoylation sites retains full biological activity in skeletal muscle.
epithelial Wnt7a and Wnt7b (show WNT7B Antibodies) are possible ligands of Fzd-mediated beta-catenin (Ctnnb1 (show CTNNB1 Antibodies))-dependent (canonical) Wnt (show WNT2 Antibodies) signaling in the adjacent undifferentiated periotic mesenchyme of fibrocytes in the murine inner ear
Binding of Wnt7a to Fzd7 (show FZD7 Antibodies) leads to an activation of noncanonical Wnt (show WNT2 Antibodies) signaling, resulting in directed myogenic stem cell migration and enhanced engraftment.
Wnt7a triggers melanocyte stem cell differentiation through beta-catenin (show CTNNB1 Antibodies) activation, and Kitl (show KITLG Antibodies) might induce following migration of melanoblasts to epidermis
This report deals with linkage studies and exome sequencing, disclosing a novel variant in WNT7A, c.934G>A (p.Gly312Ser), as the cause of this Santos syndrome.
Demonstrate a significant change in miRNA profile dependent on the assisted reproductive technology outcome affecting Wnt (show WNT2 Antibodies) pathway.
A homozygous novel WNT7A mutation was identified in a child with Al-Awadi-Raas-Rothschild syndrome accompanied by dental abnormalities and his parents with dental abnormalities.
Activation of the WNT (show WNT2 Antibodies)/CTNBB1 pathway via WNT7A might play a role in PTC (show F9 Antibodies) development.
Results show that Wnt7a expression is significantly upregulated in epithelial cells of ovarian cancer which correlates with STAT4 (show STAT4 Antibodies) expression and provide evidence that STAT4 (show STAT4 Antibodies) promotes ovarian cancer metastasis via tumor-derived Wnt7a-induced activation of cancer-associated fibroblasts.
WNT7A is a direct target of miR (show MLXIP Antibodies)-15b in ovarian cancer cell line.
The findings presented in this fetus are compatible with diagnosis of Al-Awadi-Raas-Rothschild syndrome , expanding the mutational spectrum of limb malformations arising from defects in WNT7A
Wnt7a is involved in the transformation of the retinal pigment epithelium.
Wnt7a overexpression is associated with an unfavorable prognosis and that positive Wnt7a may be an independent prognosis factor influencing OS and DFS (show FST Antibodies) prediction in colorectal cancer patients.
Wnt7a haplotype 1 had the highest haplotype frequencies and was highly significantly associated with body height, body weight, chest width and height at hip cross.
This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is involved in the development of the anterior-posterior axis in the female reproductive tract, and also plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function. Mutations in this gene are associated with Fuhrmann and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndromes.
, wingless-type MMTV integration site family, member 7A
, postaxial hemimelia
, proto-oncogene Wnt7a protein
, wingless-related MMTV integration site 7A
, wingless-type MMTV integration site 7A
, Protein Wnt-7a
, wnt-1 related (wnt-7a), wingless-type MMTV integration site family
, protein Wnt-7a-like