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Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. Additionally we are shipping ACTG2 Kits (28) and ACTG2 Proteins (8) and many more products for this protein.
Showing 10 out of 59 products:
Human Monoclonal ACTG2 Primary Antibody for IEM, ICC - ABIN335206
Chaponnier, Goethals, Janmey, Gabbiani, Gabbiani, Vandekerckhove: The specific NH2-terminal sequence Ac-EEED of alpha-smooth muscle actin plays a role in polymerization in vitro and in vivo. in The Journal of cell biology 1995
Show all 14 references for ABIN335206
Human Polyclonal ACTG2 Primary Antibody for IHC (p), WB - ABIN657460
Sun, Taurin, Sethakorn, Long, Imamura, Wang, Zimmer, Dulin, Miano: Myocardin-dependent activation of the CArG box-rich smooth muscle gamma-actin gene: preferential utilization of a single CArG element through functional association with the NKX3.1 homeodomain protein. in The Journal of biological chemistry 2009
TnT has a previously unrecognized role in forming the inactive state of regulated actin.
The terminal pointed end subunit is tilted (show OTOP1 Antibodies) towards the penultimate subunit, allowing specific and extra loop-to-loop inter-strand contacts between the two end subunits, which is not possible in other parts of the filament.
There was no significant change in the expression of TGF-beta(2 (show TGFB2 Antibodies)) and alpha-SMA (show SMN1 Antibodies) after laser-assisted intrastromal scanning.
The arrangement of actin subunits in an actin dimer assembled by tandem W domains resembles that of a long-pitch helix of the actin filament.
The distribution of laminin and alphaSMA (show ACTA2 Antibodies) in the testis and epididymis might point out to their roles in the male reproduction.
Phenotypic spectrum of ACTG2 missense variants involved severe pathology in multiple smooth muscle-dependent organs including the biliary tract and the uterus in the family with visceral myopathy.
gammaSMA expression in hepatocellular carcinoma is strongly correlated with the EMT (show ITK Antibodies) process, HCC (show FAM126A Antibodies) aggressiveness and the identification of cancer stem cells
ACTG2 encodes g2 enteric actin and is the first gene to be clearly associated with Megacystis-microcolon-intestinal hypoperistalsis syndrome, suggesting an important role for contractile proteins in enteric smooth muscle disease.
Two novel mutations in the ACTG2 gene, p.R178L and p.R178C, have been identified in two unrelated children with congenital distended bladder, microcolon, and intestinal hypoperistalsis (MMIHS).
The R148S variant in ACTG2 as a cause of autosomal dominant familial visceral myopathy in one family.
NOX4 (show NOX4 Antibodies) and ROS (show ROS1 Antibodies) have a role in myofibroblast differentiation and collagen and alpha-actin (show ACTA2 Antibodies) production of TGF- beta1 (show TGFB1 Antibodies)-induced nasal polyp-derived fibroblasts.
SMGA (show SAMD4A Antibodies) gene activity in prostate epithelia is due, in part, to the androgen-dependent expression of Nkx 3.1 (show NKX3-1 Antibodies)
RNA polymerase II accumulates in the promoter-proximal region of the dihydrofolate reductase (show DHFR Antibodies) and gamma-actin (show ACTG1 Antibodies) genes.
It was suggested that peritubular alphaSMA (show ACTA2 Antibodies)-positive myofibroblastic cells, in collaboration with interstitial macrophages, contribute to the progression of interstitial fibrosis in diabetic nephropathy.
TNF-alpha (show TNF Antibodies) suppresses TGF-beta1 (show TGFB1 Antibodies)-induced myofibroblast (fibroproliferative) phenotypic genes, for example, alpha-SMA (show SMN1 Antibodies), collagen type 1A, and fibronectin (show FN1 Antibodies) at the mRNA level.
MYOCD (show MYOCD Antibodies) can discriminate among several juxtaposed CArG elements, presumably through its novel partnership with NKX3.1 (show NKX3-1 Antibodies), to optimally transactivate the human ACTG2 promoter
Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. Three types of actins, alpha, beta and gamma, have been identified in vertebrates. Alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. This gene encodes actin gamma 2\; a smooth muscle actin found in enteric tissues. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Based on similarity to peptide cleavage of related actins, the mature protein of this gene is formed by removal of two N-terminal peptides.
actin, gamma 2, smooth muscle, enteric
, actin, gamma-enteric smooth muscle-like
, actin, gamma 2 propeptide-like
, actin, aortic smooth muscle
, alpha-smooth muscle actin
, actin, gamma-enteric smooth muscle
, gamma-enteric smooth muscle actin
, smooth muscle gamma-actin
, actin-like protein
, alpha-actin 3
, smooth muscle gamma actin