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anti-Adenosine Deaminase, RNA-Specific (ADAR) Antibodies

ADAR encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. Additionally we are shipping ADAR Proteins (7) and ADAR Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ADAR 81635 P55266
ADAR 103 P55265
ADAR 56417 Q99MU3
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Top anti-ADAR Antibodies at antibodies-online.com

Showing 10 out of 57 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using ADAR1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ICC, IF, IP, IHC (p), WB ICC/IF Image ADAR1 antibody [N3C1], Internal detects ADAR1 protein at nucleolus and nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: ADAR1 protein stained by ADAR1 antibody [N3C1], Internal , diluted at 1:200. Red: phalloidin, a cytoskeleton marker, diluted at 1:200. Blue: Hoechst 33342 staining. Scale bar = 10 μm. IHC-P Image Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using ADAR1, antibody at 1:250 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of ADAR1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of ADAR1 expression in Jurkat (A), Ramos (B), HeLa (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Mouse Un-conjugated IF, IHC (p), WB ADAR MaxPab polyclonal antibody. Western Blot analysis of ADAR expression in human liver. Western Blot analysis of ADAR expression in transfected 293T cell line by ADAR MaxPab polyclonal antibody.Lane 1: ADAR transfected lysate(134.86 KDa).Lane 2: Non-transfected lysate. 50 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human cervical cancer labeled with Anti-ADAR1 (N-terminus) Polyclonal Antibody, Unconjugated (ABIN678218) followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Rat Sheep Un-conjugated WB   50 μg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated IHC, ELISA 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated IF, IP, IHC, WB 100 μL Log in to see 14 Days
$527.15
Details

ADAR Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ADAR Antibodies

  1. Human Polyclonal ADAR Primary Antibody for WB - ABIN2774648 : Pan, Ye, Franco, Li, Yu, Zou, Zhang, Jiao, Lin: Insulin resistance and depressive symptoms in middle-aged and elderly Chinese: findings from the Nutrition and Health of Aging Population in China Study. in Journal of affective disorders 2008 (PubMed)
    Show all 2 references for ABIN2774648

  2. Human Polyclonal ADAR Primary Antibody for WB - ABIN2774647 : Zhang, Liu, Jiang, Tian, Wang, Yu: Six novel mutations of the ADAR1 gene in Chinese patients with dyschromatosis symmetrica hereditaria. in Journal of dermatological science 2008 (PubMed)
    Show all 2 references for ABIN2774647

  3. Human Polyclonal ADAR Primary Antibody for IHC, ELISA - ABIN1533787 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006 (PubMed)

  4. Human Polyclonal ADAR Primary Antibody for IF, IHC (p) - ABIN513112 : Liu, Chen, Yeh, Li, Wu, Chen, Chen, Yeh: ADAR2-mediated editing of miR-214 and miR-122 precursor and antisense RNA transcripts in liver cancers. in PLoS ONE 2014 (PubMed)

More Antibodies against ADAR Interaction Partners

Zebrafish Adenosine Deaminase, RNA-Specific (ADAR) interaction partners

  1. The presence of ADA (show ADA Antibodies) activity in zebrafish brain may be important to regulate the adenosine/inosine levels in the CNS of this species

Cow (Bovine) Adenosine Deaminase, RNA-Specific (ADAR) interaction partners

  1. These findings suggest a role of NS4A in the interaction of BVDV with ADAR that favors virus replication.

Fruit Fly (Drosophila melanogaster) Adenosine Deaminase, RNA-Specific (ADAR) interaction partners

  1. Deficiencies in the RNA-editing gene Adar increase sleep due to synaptic dysfunction in glutamatergic neurons.

  2. The study demonstrates that neuronal excitability is linked to dADAR expression levels in individual neurons.

  3. loss of Adar increases quantal size, reduces the number of quanta of neurotransmitter released and perturbs the calcium dependence of synaptic release

  4. results demonstrate a novel role for dADAR protein in rnp (show RNPC3 Antibodies)-4f 5'-UTR (show UTS2R Antibodies) alternative intron splicing regulation which is consistent with a previously proposed model.

  5. Data suggeset that RNA editing enzyme ADAR-mediated editing is more widespread than previously indicated and largely occurs cotranscriptionally.

  6. the solution structure of the N-terminal dsRNA binding domain (dsRBD) of dADAR

  7. Abolishing dADAR auto-regulation dramatically remodels the landscape of re-coding events in a site-specific manner.

  8. network-wide temporal and spatial regulation of ADAR activity can tune the complex system of RNA-editing sites and modulate multiple ethologically relevant behavioral modalities.

  9. Our study is the first to systematically characterize the temporal and spatial expression of full-length and truncated dADAR mRNA and protein isoforms during Drosophila embryogenesis.

  10. genetic analysis of dADAR substrates in Drosophila

Human Adenosine Deaminase, RNA-Specific (ADAR) interaction partners

  1. These findings suggest that adenosine deaminase acting on RNA 1 is subject to different regulations by DNA methyltransferase (show DNMT1 Antibodies) and histone deacetylase (show HDAC1 Antibodies) enzymes in neuronal SH-SY5Y cells.

  2. ADAR1 p150 (show ABL1 Antibodies) as the major A-to-I editor in mouse embryo fibroblasts.

  3. ADAR1, in an editing-independent manner, regulates the biogenesis of miR (show MLXIP Antibodies)-222 at the transcription level and thereby ICAM1 (show ICAM1 Antibodies) expression, which consequently affects melanoma immune resistance.

  4. The frame-shift mutation c.2638delG and the nonsense mutation c.2867C>A in the ADAR1 gene are associated with the dyschromatosis symmetrica hereditaria.

  5. Recent research has demonstrated that inosine in the epitranscriptome and ADAR1 protein establish innate immune tolerance for host dsRNA formed by endogenous sequences.

  6. A-to-I RNA editing levels catalyzed by ADAR1 and ADARB1 (show ADARB1 Antibodies) decreased in Alzheimer's disease patients' brain tissues, mainly in the hippocampus and to a lesser degree in the temporal and frontal lobes.

  7. A three-generation family exhibiting phenotypic variability with a single germline ADAR1 mutation suggests that chilblain might aggravate the clinical phenotypes of dyschromatosis symmetrica hereditaria.

  8. The function of primary RNA editing enzyme ADAR1 in pluripotent stem cells was investigated and found that loss of ADAR1 in human iPS (show SLC27A4 Antibodies) cells promotes caspase3-mediated cell death.

  9. Data show that the protein levels of polypyrimidine tract binding protein 1 (PTBP1 (show PTBP1 Antibodies)) and adenosine deaminase RNA-specific binding protein ADAR1 were cooperatively expressed in glioma tissues and cells.

  10. In conclusion, we have found ten novel mutations in the ADAR1 of 7 dyschromatosis symmetrica hereditaria pedigrees and 3 sporadic individuals.

Mouse (Murine) Adenosine Deaminase, RNA-Specific (ADAR) interaction partners

  1. Thus, Adarb1 (show ADARB1 Antibodies) and Adarb2 (show ADARB2 Antibodies) have nearly exclusive expression within brain tissue, while Adar has more appreciable expression across multiple tissues.

  2. After fear conditioning protocol, mRNA expression of ADAR1 increased in amygdala and hippocampus.

  3. ADAR1 is an essential molecule for maintaining adult liver homeostasis and, in turn, morphological and functional integrity.

  4. The p150 (show ABL1 Antibodies) isoform of ADAR1 uniquely regulated the MDA5 (show IFIH1 Antibodies) pathway.

  5. transcriptional activation of Adar1 by IFN occurs in the absence of STAT1 (show STAT1 Antibodies) by a non-canonical STAT2 (show STAT2 Antibodies)-dependent pathway in mouse but not human cells.

  6. A-to-I editing of endogenous dsRNA is the essential function of ADAR1, preventing the activation of the cytosolic dsRNA response by endogenous transcripts.

  7. ADAR1 mutations causing Aicardi-Goutieres syndrome affect the activity of the interferon (show IFNA Antibodies)-inducible cytoplasmic isoform more severely than the nuclear isoform.

  8. Analysis of editing in the filamin A (show FLNA Antibodies) encoding mRNA shows very high editing levels outside the nervous system; further shows FLNA (show FLNA Antibodies) editing is mainly achieved by ADAR2 (show ADARB1 Antibodies) but that in some cases ADAR1 can efficiently compensate for ADAR2 (show ADARB1 Antibodies).

  9. Adenosine deaminase acting on RNA 1 limits RIG-I (show DDX58 Antibodies) RNA detection and suppresses IFN production responding to viral and endogenous RNAs.

  10. Loss of ADAR1 induced ER stress and activation of IFN signaling, and altered expression in WNT (show WNT2 Antibodies) targets, followed by intestinal inflammation.

ADAR Antigen Profile

Protein Summary

This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with ADAR

  • adenosine deaminase, RNA-specific (adar) antibody
  • adenosine deaminase, RNA-specific (ADAR) antibody
  • Adenosine deaminase acting on RNA (Adar) antibody
  • adenosine deaminase acting on RNA (Adar) antibody
  • adenosine deaminase acting on RNA (CpipJ_CPIJ011849) antibody
  • adenosine deaminase, RNA-specific (Adar) antibody
  • adar antibody
  • Adar1 antibody
  • adr antibody
  • AGS6 antibody
  • AV242451 antibody
  • cg12598 antibody
  • dAdar antibody
  • Dmel\\CG12598 antibody
  • DRADA antibody
  • DSH antibody
  • DSRAD antibody
  • dsRAD-1 antibody
  • EG:BACN35H14.1 antibody
  • G1P1 antibody
  • hypnos-2 antibody
  • IFI-4 antibody
  • IFI4 antibody
  • K88DSRBP antibody
  • mZaADAR antibody
  • NV18763 antibody
  • P136 antibody
  • red1 antibody
  • wu:fc22a02 antibody

Protein level used designations for ADAR

double-stranded RNA-specific adenosine deaminase , dsRNA adenosine deaminase , adenosine deaminase, RNA-specific , RNA-specific adenosine deaminase , Adar-PA , Adar-PB , Adar-PC , Adar-PD , Adar-PE , Adar-PF , Adar-PH , Adar-PI , Adar-PJ , Adar-PK , Adar-PL , Adar-PM , CG12598-PA , CG12598-PB , CG12598-PC , CG12598-PD , CG12598-PE , CG12598-PF , CG12598-PH , CG12598-PI , CG12598-PJ , CG12598-PK , CG12598-PL , CG12598-PM , adenosine deaminase acting on RNA , adenosine deaminases acting on RNA , hypoxia, anoxia, sensitive 2 , DRADA , 136 kDa double-stranded RNA-binding protein , adenosine deaminase acting on RNA 1-A , interferon-induced protein 4 , interferon-inducible protein 4 , RNA adenosine deaminase 1 , RNA-specific adenosine deaminase p110 form , RNA-specific adenosine deaminase p150 form

GENE ID SPECIES
58119 Danio rerio
397992 Xenopus laevis
505134 Bos taurus
769675 Gallus gallus
31130 Drosophila melanogaster
408529 Apis mellifera
6044765 Culex quinquefasciatus
100114127 Nasonia vitripennis
81635 Rattus norvegicus
103 Homo sapiens
56417 Mus musculus
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