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NPEPPS encodes the puromycin-sensitive aminopeptidase, a zinc metallopeptidase which hydrolyzes amino acids from the N-terminus of its substrate. Additionally we are shipping Aminopeptidase Puromycin Sensitive Proteins (9) and Aminopeptidase Puromycin Sensitive Kits (4) and many more products for this protein.
Showing 10 out of 62 products:
Human Polyclonal NPEPPS Primary Antibody for EIA, WB - ABIN453303
Thompson, Hersh: Analysis of conserved residues of the human puromycin-sensitive aminopeptidase. in Peptides 2004
Human Polyclonal NPEPPS Primary Antibody for ELISA, WB - ABIN238593
Karsten, Sang, Gehman, Chatterjee, Liu, Lawless, Sengupta, Berry, Pomakian, Oh, Schulz, Hui, Wiedau-Pazos, Vinters, Binder, Geschwind, Jackson: A genomic screen for modifiers of tauopathy identifies puromycin-sensitive aminopeptidase as an inhibitor of tau-induced neurodegeneration. in Neuron 2006
findings show that by promoting autophagic protein clearance, PSA helps protect against accumulation of aggregation-prone proteins and proteotoxicity
the purification and characterization of a puromycin-sensitive aminopeptidase from zebrafish
cytosolic peptidases(puromycin-sensitive aminopeptidase (PSA), aminopeptidase B (APB (show RNPEP Antibodies)) and pyroglutamyl-peptidase I (show PGPEP1 Antibodies) (PGI (show BGN Antibodies)) ) may be involved in colorectal carcinogenesis
Studies indicate the critical role of M1 aminopeptidases ERAP1 (show ERAP1 Antibodies), ERAP2 (show ERAP2 Antibodies) and NPEPPS in immune-mediated diseases.
MiR (show MLXIP Antibodies)-614 inhibited cell invasion and proliferationa targeting PSA (show PLAG1 Antibodies) in lung cancer cells, PGCL3
Elevation of NPEPPS activity blocks accumulation of hyperphosphorylated TAU protein and slows down the progression of Alzheimer's disease.
findings show that by promoting autophagic protein clearance, PSA (show PLAG1 Antibodies) helps protect against accumulation of aggregation-prone proteins and proteotoxicity
ApPS (show CTSB Antibodies) Y394F exhibited a 3.3-fold lower affinity for RB-3014, a transition state inhibitor, indicating that Tyr394 is involved in transition state stabilization
PSA (show PLAG1 Antibodies) gene was downregulated in PC-3 (show PCSK1 Antibodies) cells that were treated with CoCl(2). PSA (show PLAG1 Antibodies) is involved in the proliferation, migration, and invasion of PC-3 (show PCSK1 Antibodies) cells, which are important determinants of metastasis, via a mechanism that involves MMP-9 (show MMP9 Antibodies) modulation.
Nucleocytoplasmic transfer of cyclin dependent kinase 5 (show CDK5 Antibodies) and its binding to puromycin-sensitive aminopeptidase in Dictyostelium discoideum
These data indicate that PSA may play a role in limiting MHC class I Ag presentation in dendritic cells in vivo but that it is not essential for generating most MHC class I-presented peptides or for stimulating CTL responses to several Ags (show GLA Antibodies).
This gene encodes the puromycin-sensitive aminopeptidase, a zinc metallopeptidase which hydrolyzes amino acids from the N-terminus of its substrate. The protein has been localized to both the cytoplasm and to cellular membranes. This enzyme degrades enkaphalins in the brain, and studies in mouse suggest that it is involved in proteolytic events regulating the cell cycle.
, lethal (3) 06226
, puromycin sensitive aminopeptidase
, puromycin-sensitive aminopeptidase
, aminopeptidase puromycin sensitive
, puromycin-sensitive aminopeptidase-like
, cytosol alanyl aminopeptidase
, metalloproteinase MP100