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anti-Ankyrin 2, Neuronal (ANK2) Antibodies

ANK2 encodes a member of the ankyrin family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton. Additionally we are shipping ANK2 Kits (28) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ANK2 109676 Q8C8R3
ANK2 287 Q01484
ANK2 362036  
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Top anti-ANK2 Antibodies at antibodies-online.com

Showing 10 out of 92 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated ICC, IF, IHC, WB Western Blotting rat brain membrane 1 in 1000 AnkyrinB. 100 μg Log in to see 3 to 4 Days
$383.90
Details
Human Mouse Un-conjugated FM, ELISA, WB Western blot analysis of Ankyrin B. Rat brain lysates were probed with 2 µg/ml (lane 1) or 5 µg/ml (lane 2) of the mouse anti-ankyrin B antibody (clone 2.20). Ankyrin B isoforms can be observed at ~150 and ~220 kDa, respectively. 0.1 mg Log in to see 5 to 6 Days
$237.77
Details
Human Mouse HRP ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$422.40
Details
Human Mouse FITC ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$426.80
Details
Human Mouse Alkaline Phosphatase (AP) ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$429.00
Details
Human Mouse Biotin ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$431.20
Details
Human Mouse PE ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$432.30
Details
Human Mouse Streptavidin ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$433.40
Details
Human Mouse PerCP ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$434.50
Details
Human Mouse APC ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$434.50
Details

ANK2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ANK2 Antibodies

  1. Human Monoclonal ANK2 Primary Antibody for FM, ELISA - ABIN967633 : Scotland, Zhou, Benveniste, Bennett: Nervous system defects of AnkyrinB (-/-) mice suggest functional overlap between the cell adhesion molecule L1 and 440-kD AnkyrinB in premyelinated axons. in The Journal of cell biology 1999 (PubMed)
    Show all 5 references for ABIN967633

  2. Human Monoclonal ANK2 Primary Antibody for ICC, IF - ABIN2485095 : Bennett, Baines: Spectrin and ankyrin-based pathways: metazoan inventions for integrating cells into tissues. in Physiological reviews 2001 (PubMed)

More Antibodies against ANK2 Interaction Partners

Mouse (Murine) Ankyrin 2, Neuronal (ANK2) interaction partners

  1. The identification and characterization of two functionally distinct ankyrin-B isoforms in heart provide compelling evidence that alternative splicing of the ANK2 gene regulates the fidelity of ankyrin-B interactions with proteins

  2. Taken together, these observations reveal that AnkB (show ANKH Antibodies) is required for Prx (show PRX Antibodies) membrane anchoring and for maintenance of lens fiber cell hexagonal geometry, membrane skeleton organization, and biomechanics.

  3. that ankyrin-B deficiency results in a metabolic syndrome that combines primary pancreatic beta cell insufficiency with peripheral insulin (show INS Antibodies) resistance

  4. Functional relationships between PIK3C3 (show PIK3C3 Antibodies), dynactin (show DCTN1 Antibodies), and AnkB (show ANKH Antibodies) promote axonal transport of organelles and are required for normal axon length.

  5. These findings identify an interaction between ankyrin-B and both Cav2.1 (show CACNA1A Antibodies) and Cav2.2 (show CACNA1B Antibodies) at the amino acid level that is necessary for proper Cav2.1 (show CACNA1A Antibodies) and Cav2.2 (show CACNA1B Antibodies) targeting in vivo.

  6. Ankyrin-B protein (show LEPREL2 Antibodies) in heart failure: identification of a new component of metazoan cardioprotection.

  7. AnkB (show ANKH Antibodies) reduction alters cardiac Na and Ca transport and enhances the coupled RyR (show RYR1 Antibodies) openings, resulting in more frequent Ca sparks and waves although the total SR Ca leak is unaffected.

  8. Ankyrin-B then interacts with dynactin-4 (show DCTN5 Antibodies) and dystrophin (show DMD Antibodies), whereas dynactin-4 (show DCTN5 Antibodies) collaborates with dystrophin (show DMD Antibodies) in coordinating costamere-aligned microtubules

  9. Ankyrin-B regulates Kir6.2 (show KCNJ11 Antibodies) membrane expression and function in heart.

  10. Findings highlight the importance of the functional anatomy of the entire atrial distributed pacemaker complex and clearly demonstrate the role of AnkB (show ANKH Antibodies) in cardiac automaticity.

Human Ankyrin 2, Neuronal (ANK2) interaction partners

  1. The identification and characterization of two functionally distinct ankyrin-B isoforms in heart provide compelling evidence that alternative splicing of the ANK2 gene regulates the fidelity of ankyrin-B interactions with proteins

  2. the structures of ANK (show ANK1 Antibodies) repeats in complex with an inhibitory segment from the C-terminal regulatory domain and with a sodium channel Nav1.2 (show SCN2A Antibodies) peptide, are reported.

  3. Gankyrin (show PSMD10 Antibodies) plays an essential role in estrogen-driven and GPR30 (show GPER Antibodies)-mediated endometrial carcinoma cell proliferation via the PTEN (show PTEN Antibodies)/PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) signaling pathway.

  4. ankyrin-B linker suppresses activity of the ANK (show ANK1 Antibodies) repeat domain through an intramolecular interaction, likely with a groove on the surface of the ANK (show ANK1 Antibodies) repeat solenoid, thereby regulating the affinities between ankyrin-B and its binding partners

  5. Residues 63-73 of cdB3 is also essential for ankyrin binding.

  6. Ankyrin-B protein (show LEPREL2 Antibodies) in heart failure: identification of a new component of metazoan cardioprotection.

  7. Reduced ankyrin-B expression or mutations in ankyrin 2 are associated with atrial fibrillation.

  8. Data show that DAnk2-binding is critical for beta spectrin function in vivo.

  9. The common genetic variation in the ANK2 gene is modified the physiological variability of the QT interval in the general population.

  10. The ankyrin-B C-terminal domain determines activity of ankyrin-B/G chimeras

ANK2 Antigen Profile

Protein Summary

This gene encodes a member of the ankyrin family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton. Ankyrins play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats\; a central region with a highly conserved spectrin binding domain\; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. The protein encoded by this gene is required for targeting and stability of Na/Ca exchanger 1 in cardiomyocytes. Mutations in this gene cause long QT syndrome 4 and cardiac arrhythmia syndrome. Multiple transcript variants encoding different isoforms have been described.

Gene names and symbols associated with ANK2

  • ankyrin 2, neuronal (ANK2) antibody
  • ankyrin 2b, neuronal (ank2b) antibody
  • ankyrin-2-like (LOC539238) antibody
  • ankyrin 2, neuronal (ank2) antibody
  • ankyrin repeat and zinc finger domain containing protein 1 (PTRG_09290) antibody
  • ankyrin 2, brain (Ank2) antibody
  • ankyrin 2, neuronal (Ank2) antibody
  • AI835472 antibody
  • ANK-2 antibody
  • ANK2 antibody
  • Ank3 antibody
  • ANKB antibody
  • AW491075 antibody
  • brank-2 antibody
  • CHANK2 antibody
  • LQT4 antibody
  • zgc:101738 antibody

Protein level used designations for ANK2

ankyrin 2, neuronal , ankyrin-2-like , ankyrin repeat and zinc finger domain containing protein 1 , ankyrin-2 , ankyrin-B , brain ankyrin , ankyrin B , ankyrin, brain , ankyrin-2, nonerythrocytic , non-erythroid ankyrin , ankyrin 2, brain , ankyrin 3, epithelial

GENE ID SPECIES
422689 Gallus gallus
450043 Danio rerio
461444 Pan troglodytes
539238 Bos taurus
100010497 Monodelphis domestica
100064198 Equus caballus
100076099 Ornithorhynchus anatinus
100176624 Ciona intestinalis
100436372 Pongo abelii
100465763 Ailuropoda melanoleuca
702180 Macaca mulatta
100512728 Sus scrofa
6347580 Pyrenophora tritici-repentis Pt-1C-BFP
109676 Mus musculus
287 Homo sapiens
362036 Rattus norvegicus
487908 Canis lupus familiaris
Selected quality suppliers for anti-ANK2 (ANK2) Antibodies
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