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Annexin A2 Proteins (ANXA2)

ANXA2 encodes a member of the annexin family. Additionally we are shipping Annexin A2 Antibodies (190) and Annexin A2 Kits (47) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ANXA2 302 P07355
ANXA2 12306 P07356
ANXA2 56611 Q07936
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Top Annexin A2 Proteins at

Showing 10 out of 43 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 Days
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
HOST_Escherichia coli (E. coli) Human His tag 10% SDS-PAGE stained with Coomassie Blue (CB), immunobloting with anti-6xHis (WB) serum and peptide fingerprinting by MALDI-TOF-TOF mass spectrometry 50 μg Log in to see 5 to 7 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
HOST_Escherichia coli (E. coli) Human GST tag Annexin A2 (ANXA2) (AA 1-339), (full length) protein (GST tag) 1 mg Log in to see 56 to 66 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 5 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 11 Days
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days

ANXA2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, , ,
Mouse (Murine) ,

Rat (Rattus)

Top referenced Annexin A2 Proteins

  1. Human Annexin A2 Protein expressed in Escherichia coli (E. coli) - ABIN666939 : Emans, Gorvel, Walter, Gerke, Kellner, Griffiths, Gruenberg: Annexin II is a major component of fusogenic endosomal vesicles. in The Journal of cell biology 1993 (PubMed)
    Show all 2 references for ABIN666939

  2. Human Annexin A2 Protein expressed in Wheat germ - ABIN1345180 : Bhattacharjee, Ahamed, Pawlinski, Liu, Mackman, Ruf, Edgington: Factor Xa binding to annexin 2 mediates signal transduction via protease-activated receptor 1. in Circulation research 2008 (PubMed)
    Show all 2 references for ABIN1345180

  3. Human Annexin A2 Protein expressed in HEK-293 Cells - ABIN2714737 : Deng, Lei, Zhang, Zhang, Zheng, Zhang, Pan, Wang, Tian, Shen, Zhao, Lundberg, Liu, Papasian, Deng: Peripheral blood monocyte-expressed ANXA2 gene is involved in pathogenesis of osteoporosis in humans. in Molecular & cellular proteomics : MCP 2011 (PubMed)

More Proteins for Annexin A2 (ANXA2) Interaction Partners

Horse (Equine) Annexin A2 (ANXA2) interaction partners

  1. ANXA2 and MMP1 (show MMP1 Proteins) might participate in remodeling during wound healing in the horse.

Cow (Bovine) Annexin A2 (ANXA2) interaction partners

  1. annexin A2-induced actin bundling is apparently essential for generating active exocytotic sites.

  2. Calves that later developed pneumonia had significantly lower levels of annexin A1 (show ANXA1 Proteins) and annexin A2, which are potential biomarkers of increased susceptibility to pneumonia in recently weaned and transported feedlot cattle.

  3. Because annexins I and II are abundant and have functions important to the maintenance of placentation, the down-regulation of the annexin genes in the cultured NT (nuclear transfer) trophectoderm may be related to the frequent failures of NT pregnancies.

  4. annexin II binds to CEACAM1 (show CEACAM1 Proteins) in a breast neoplasm model

  5. show for the first time that annexin A2 (AIIt) can undergo functional reactivation by glutaredoxin (show GRX1 Proteins), therefore establishing that AIIt is regulated by reversible glutathionylation

  6. AII (show NLRP3 Proteins) does not bind 1,25-D(3) in a physiologically relevant manner

  7. Data show that the mRNA-binding site of Annexin A2 resides in its domain IV.

  8. The results showed that alkaline phosphatase (ALP) activity was significantly increased in matrix vesicles from calcified bovine vascular smooth muscle cells (BVSMCs) compared with noncalcified BVSMCs, as was annexin II and VI content and (45)Ca uptake.

Human Annexin A2 (ANXA2) interaction partners

  1. Rack1 regulated P-Glycoprotein activity, which was necessary for adriamycin-induced P-Glycoprotein - mediated phosphorylation of Anxa2 and Erk1/2.

  2. The presence of vascular lesions in lupus nephritis (LN) appears to be associated with significant differences in the vascular expression of ANXA2.

  3. annexin A2 but not follistatin (show FST Proteins) is expressed in hepatocellular carcinoma

  4. Our results place ANXA2 at the apex (show APEX1 Proteins) of a regulatory cascade that determines glioblastoma mesenchymal transformation and validate aSICS as a general methodology to uncover regulators of cancer subtypes.

  5. Overexpression of ANXA2 is associated with colorectal cancer.

  6. Annexin A2, up-regulated by IL-6 (show IL6 Proteins), promotes ligament ossification in ankylosing spondylitis patients.

  7. highly specific 30 kDa plant lectin could dissociate AnxA2 from endogenous lectin galectin-3 (show LGALS3 Proteins) interaction at the cell surface. This dissociation could down-regulate Bcl-2 (show BCL2 Proteins) family proteins, cell proliferation, and migration simultaneously triggering cell apoptosis

  8. Data show that ONECUT2, IGF2BP1 (show IGF2BP1 Proteins), and ANXA2 proteins were confirmed to be microRNA-9 (miR (show MLXIP Proteins)-9) targets and aberrantly upregulated in hepatocellular carcinoma (HCC (show FAM126A Proteins)).

  9. annexin A2 and S100A10 (show S100A10 Proteins) expressions are powerful predictors of serous ovarian cancer outcome.

  10. expression of ANXA2 is associated with tumorigenesis and therapeutic resistance of nasopharyngeal carcinoma

Pig (Porcine) Annexin A2 (ANXA2) interaction partners

  1. In conclusion, Annexin 2 is the novel host protein identified to interact with classical swine fever virus E2 and promote virus multiplication.

  2. Amino acids R338, N359, G378 of NS5A were revealed to be pivotal for the ANXA2-NS5A interaction.

  3. Taken together, these results indicate that Nsp9 binding partner ANXA2 is beneficial for porcine reproductive and respiratory syndrome virus replication.

  4. Annexin A2 acts in exocytic apical membrane trafficking in small intestinal enterocytes and is proteolytically cleaved in situ by pancreatic proteinases once it has become externalized to the lumenal side of the brush border membrane. [annexin A2]

  5. An octameric model is proposed for the annexin A2/p11(S100A10 (show S100A10 Proteins)) complex, which exerts annexin A2 function. The proposed structure of the annexin A2/p11 (show S100A10 Proteins) octamer sheds new light into annexin A2/p11 (show S100A10 Proteins) interaction.

Mouse (Murine) Annexin A2 (ANXA2) interaction partners

  1. Podxl (show PODXL Proteins)-overexpression in neural stem/progenitor cells leads to an up-regulation of Annexin A2.

  2. The tick protein sialostatin L2 binds to annexin A2 and inhibits NLRC4 (show NLRC4 Proteins)-mediated inflammasome activation.

  3. Data show that annexin A2 (AnxA2) directly exerted negative regulation of inflammatory responses through Toll-like receptor 4 (TLR4 (show TLR4 Proteins))-initiated TRAM protein (show TRAM2 Proteins)-TRIF (show RNF138 Proteins) protein pathway occurring on endosomes.

  4. The role of ARF-6 (show ARF6 Proteins) and Annexin A2 in the invasion of mammalian cells by T. cruzi amastigotes.

  5. Taken together, these findings indicate for the first time that AnxA2 phosphorylation and actin remodeling evoked by oxidative stress depend on the sphingolipid pathway, via MMP2 (show MMP2 Proteins) and p38MAPK (show MAPK14 Proteins).

  6. Data indicate that annexin A2 (AnxA2) regulates the secretion of semaphorin 3D (Sema3D (show SEMA3D Proteins)) from pancreatic ductal adenocarcinoma (PDA) cells.

  7. results suggest that legumain (show LGMN Proteins) expression and activation and cleavage of annexin A2 are regulated by DJ-1 (show PARK7 Proteins) through p53 (show TP53 Proteins)

  8. AnxA2 regulates autophagy, thereby contributing to host immunity against bacteria through the Akt1 (show AKT1 Proteins)-mTOR (show FRAP1 Proteins)-ULK1 (show ULK1 Proteins)/2 signaling pathway

  9. These data suggest that AnxA2 and AnxA5 (show ANXA5 Proteins) can influence bone formation via regulation of osteoprogenitor proliferation, differentiation, and responsiveness to cytokines in addition to their well-studied function in matrix vesicles

  10. The tumor microenvironment interaction between ANXA2-CXCL12 (show CXCL12 Proteins) is critical for metastatic phenotypes and may impact chemotherapeutic potential.

Annexin A2 (ANXA2) Protein Profile

Protein Summary

This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Annexin A2 Proteins (ANXA2)

  • annexin A2 (anxa9)
  • annexin A2 (anxa2)
  • annexin A2 (ANXA2)
  • annexin A2 (Anxa2)
  • annexin A2 (LOC100357671)
  • ANX2 protein
  • ANX2L4 protein
  • ANXA2 protein
  • AW215814 protein
  • Cal1h protein
  • LIP2 protein
  • LPC2 protein
  • LPC2D protein
  • MGC53008 protein
  • MGC76145 protein
  • P36 protein
  • pap-i protein
  • PAP-IV protein

Protein level used designations for Annexin A2 Proteins (ANXA2)

annexin A2 , annexin II , Lipocortin II , annexin A2-like , PAP-IV , annexin-2 , calpactin I heavy chain , calpactin-1 heavy chain , chromobindin-8 , lipocortin II , p36 , placental anticoagulant protein IV , protein I , calpactin I heavy polypeptide , chromobindin 8 , annexin 2 , 33-kDa calcimedin , 33-kDa lymphocyte Ca<2+>- binding protein , 33kDa lymphocyte Ca<2+>- binding protein , 36-kDa calelectrin

380380 Xenopus laevis
394517 Xenopus (Silurana) tropicalis
706240 Macaca mulatta
747018 Pan troglodytes
100054320 Equus caballus
100397902 Callithrix jacchus
282689 Bos taurus
302 Homo sapiens
396297 Gallus gallus
403435 Canis lupus familiaris
406192 Sus scrofa
12306 Mus musculus
56611 Rattus norvegicus
100357671 Oryctolagus cuniculus
100716883 Cavia porcellus
100048993 Ovis aries
100173821 Pongo abelii
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