Annexin A2 Protein (ANXA2) (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2714737

This Recombinant Annexin A2 protein is expressed in HEK-293 Cells and has been mentioned in 1 publication.

Quick Overview for Annexin A2 Protein (ANXA2) (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2714737)

Target: Annexin A2 (ANXA2)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 2

Purification tag / Conjugate: This Annexin A2 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human Annexin A2 / ANXA2 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

References

Deng, Lei, Zhang, Zhang, Zheng, Zhang, Pan, Wang, Tian, Shen, Zhao, Lundberg, Liu, Papasian, Deng: "Peripheral blood monocyte-expressed ANXA2 gene is involved in pathogenesis of osteoporosis in humans." in: Molecular & cellular proteomics : MCP, Vol. 10, Issue 11, pp. M111.011700, (2011) (PubMed).

Target Details

Target: Annexin A2 (ANXA2)

Alternative Name: Annexin a2,anxa2

Background: This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 38.4 kDa

NCBI Accession: NP_001002857

Pathways: S100 Proteins