Annexin A2 Protein (ANXA2) (AA 2-339) (His tag)
-
- Target See all Annexin A2 (ANXA2) Proteins
- Annexin A2 (ANXA2)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 2-339
-
Origin
- Mouse
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Annexin A2 protein is labelled with His tag.
- Purpose
- Mouse ANXA2 Protein
- Sequence
- Ser2-Asp339
- Characteristics
- Recombinant Mouse ANXA2 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Ser2-Asp339.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
-
Annexin A2 (ANXA2) (AA 19-357) protein (GST tag)
ANXA2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Annexin A2 (ANXA2) (AA 1-339) protein (GST tag)ANXA2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Annexin A2 (ANXA2) (AA 2-339) protein (His tag)ANXA2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Annexin A2 (ANXA2) (AA 186-268) protein (GST tag)ANXA2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Annexin A2 (ANXA2) (AA 2-339) protein (His tag)Crystallography grade ANXA2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Annexin A2 (ANXA2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)ANXA2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in 20 mM MES, 150 mM NaCl, 200 mM L-arginine, 5 mM DTT ( pH 5.5).
- Buffer
- Lyophilized from 0.22μm filtered solution in 20 mM MES, 150 mM NaCl, 200 mM L-arginine, 5 mM DTT ( pH 5.5). Normally 8 % trehalose is added as protectant before lyophilization.
- Preservative
- Dithiothreitol (DTT)
- Precaution of Use
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- Annexin A2 (ANXA2)
- Alternative Name
- ANXA2 (ANXA2 Products)
- Synonyms
- ANX2 Protein, ANX2L4 Protein, CAL1H Protein, LIP2 Protein, LPC2 Protein, LPC2D Protein, P36 Protein, PAP-IV Protein, AW215814 Protein, Cal1h Protein, p36 Protein, anx2 Protein, lip2 Protein, lpc2 Protein, cal1h Protein, lpc2d Protein, pap-i Protein, anx2l4 Protein, MGC76145 Protein, ANXA2 Protein, anxa2 Protein, anxa2-a Protein, anxa2-b Protein, annexin A2 Protein, annexin A2 S homeolog Protein, ANXA2 Protein, Anxa2 Protein, anxa2 Protein, anxa2.S Protein
- Background
- ANXA2, highly expressed in invasive breast cancer cells, is closely related with poor prognosis, and acts as a molecular switch to EGFR activation. ANXA2 expression is inversely correlated with cell sensitivity to gefitinib. Knockdown of ANXA2 expression in MDA-MB-231 cells increased the gefitinib induced cell death. When ANXA2 was overexpressed in MCF7 cells, the gefitinib induced cell death was decreased. Furthermore, the phosphorylation of ANXA2 at Tyr23 is negatively correlated with the sensitivity of TNBC to gefitinib.
- Molecular Weight
- 39.6 kDa same as Tris-Bis PAGE result.
- UniProt
- P07356
- Pathways
- S100 Proteins
-
