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APOL1 encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Additionally we are shipping APOL1 Kits (27) and APOL1 Proteins (4) and many more products for this protein.
Showing 10 out of 108 products:
Human Monoclonal APOL1 Primary Antibody for WB - ABIN2869387
Vanhollebeke, Nielsen, Watanabe, Truc, Vanhamme, Nakajima, Moestrup, Pays: Distinct roles of haptoglobin-related protein and apolipoprotein L-I in trypanolysis by human serum. in Proceedings of the National Academy of Sciences of the United States of America 2007
Show all 2 references for ABIN2869387
Human Monoclonal APOL1 Primary Antibody for ELISA, WB - ABIN968963
Albert, Duchateau, Deeb, Pullinger, Cho, Heilbron, Malloy, Kane, Brown: Apolipoprotein L-I is positively associated with hyperglycemia and plasma triglycerides in CAD patients with low HDL. in Journal of lipid research 2005
Show all 2 references for ABIN968963
Human Polyclonal APOL1 Primary Antibody for IHC (p), WB - ABIN391541
Li, Fan, Bai, Liu, Huang, Wang, Wu, Liu, Liu: Distribution and effect of apoL-I genotype on plasma lipid and apolipoprotein levels in Chinese normalipidemic and endogenous hypertriglyceridemic subjects. in Clinica chimica acta; international journal of clinical chemistry 2009
Human Polyclonal APOL1 Primary Antibody for ELISA, WB - ABIN1534643
Page, Butlin, Lomthaisong, Lowry: The human apolipoprotein L gene cluster: identification, classification, and sites of distribution. in Genomics 2001
Human Polyclonal APOL1 Primary Antibody for ELISA, WB - ABIN308434
Pérez-Morga, Vanhollebeke, Paturiaux-Hanocq, Nolan, Lins, Homblé, Vanhamme, Tebabi, Pays, Poelvoorde, Jacquet, Brasseur, Pays: Apolipoprotein L-I promotes trypanosome lysis by forming pores in lysosomal membranes. in Science (New York, N.Y.) 2005
Sociodemographic factors and common risk factors for chronic kidney disease progression do not seem to alter APOL1-related CKD progression.
APOL1 G1 and G2 genotypes in deceased African American liver donors have minimal effects on liver transplant outcomes.
blacks with two APOL1 risk alleles had the highest risk for albuminuria and eGFRcys decline in young adulthood, whereas disparities between low-risk blacks and whites were related to differences in traditional risk factors.
we have shown that individuals with the high risk APOL1 genotype enrolled in the NEPTUNE (show KLF17 Antibodies) study present, from a clinical and histologic perspective, with more advanced disease and have less remission of proteinuria over time.
Only APOL1 G1 and G2 confer renal risk, and other common and rare APOL1 missense variants, including the archaic G3 haplotype, do not contribute to sporadic FSGS (show ACTN4 Antibodies) and HIVAN in the US population.
Expression of either G1 or G2 APOL1 variants increased cell swelling and death vs G0-expressing cells. This was preceded by G1 or G2 APOL1-induced net efflux of intracellular potassium, resulting in the activation of stress-activated protein kinases.
APOL1 genotype is associated with albuminuria, subclinical atherosclerosis, incident myocardial infarction, and mortality in older African Americans.
This review provides an update on the biological functions for circulating (trypanosome resistance) and intracellular (emerging role for autophagy) APOL1.
Higher levels of factor VIIc, VIIIc (show COX7A1 Antibodies), fibrinogen, vonWillebrand factor, and protein C (show PROC Antibodies) were associated with ESRD risk, with a significantly stronger association of factor VIIIc (show COX7A1 Antibodies) and protein C (show PROC Antibodies) in African Americans with two APOL1 risk alleles.
Apolipoprotein L1 gene variants in deceased organ donors are associated with renal allograft failure.
This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene.