You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Ataxin 1 (ATXN1) Antibodies

The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Additionally we are shipping Ataxin 1 Kits (33) and Ataxin 1 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ATXN1 6310 P54253
ATXN1 20238 P54254
ATXN1 25049 Q63540
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-Ataxin 1 Antibodies at antibodies-online.com

Showing 10 out of 202 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from HepG2 cells treated with Adriamycin 0.5uM 5h, using Ataxin 1 (Phospho-Ser776) Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of NIH-3T3 cells, using Ataxin 1 (Phospho-Ser776) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF, WB Western blot analysis of anti-ATXN1 Antibody (S776) (ABIN389309) in CEM cell line lysates (35 µg/lane). ATXN1 (arrow) was detected using the purified polyclonal antibody. Confocal immunofluorescent analysis of ATXN1 Antibody (S776)(ABIN389309) with hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Ataxin 1 (Ab-776) Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of NIH-3T3 cells, using Ataxin 1 (Ab-776) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated FM, ICC, IHC, ELISA, WB Figure 1: Flow cytometric analysis of Jurkat cells using ATXN1 mouse mAb (green) and negative control (purple) . Figure 2: Immunofluorescence analysis of NTERA-2 cells using ATXN1 mouse mAb (green) . Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. 100 μL Log in to see 3 to 4 Days
$393.80
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- Ataxin 1 Picoband antibody, Western blotting All lanes: Anti Ataxin 1  at 0.5ug/ml Lane 1: MCF-7 Whole Cell Lysate at 40ug Lane 2: COLO320 Whole Cell Lysate at 40ug Lane 3: PANC Whole Cell Lysate at 40ug Predicted bind size: 87KD Observed bind size: 87KD Anti- Ataxin 1 Picoband antibody, IHC(P) IHC(P): Human Lung Cancer Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated IF, IHC (p), ELISA Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB Anti- ATAXIN1 antibody, Western blotting All lanes: Anti ATAXIN1  at 0.5ug/ml WB: SMMC Whole Cell Lysate at 40ug Predicted bind size: 87KD Observed bind size: 87KD 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Mouse Un-conjugated EIA, FACS, IF, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p) Immunofluorescence analysis of NIH-3T3 cells, using Ataxin 1 (Ab-776) Antibody. The picture on the right is treated with the synthesized peptide. Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details

ATXN1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
, ,
,
, , , , , , , , , , , , , , , , , , ,
Mouse (Murine) , , , ,
, , ,
,
, , , , , , , , , , , , , , , , , , ,
Rat (Rattus) , ,
, ,
,
, , , , , , , , , , , , , , , , , , ,

Top referenced anti-Ataxin 1 Antibodies

  1. Human Monoclonal Ataxin 1 Primary Antibody for EIA, FACS - ABIN1105458 : Krishna, Mohan, Yashavantha, Rammurthy, Kiran Kumar, Mittal, Tyagi, Mukerji, Jain, Pal, Purushottam: SCA 1, SCA 2 & SCA 3/MJD mutations in ataxia syndromes in southern India. in The Indian journal of medical research 2007 (PubMed)
    Show all 4 references for ABIN1105458

  2. Human Polyclonal Ataxin 1 Primary Antibody for EIA, WB - ABIN357975 : Lim, Crespo-Barreto, Jafar-Nejad, Bowman, Richman, Hill, Orr, Zoghbi: Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1. in Nature 2008 (PubMed)
    Show all 2 references for ABIN357975

  3. Human Polyclonal Ataxin 1 Primary Antibody for IF, WB - ABIN389309 : Hong, Lee, Cho, Kang: UbcH6 interacts with and ubiquitinates the SCA1 gene product ataxin-1. in Biochemical and biophysical research communications 2008 (PubMed)
    Show all 2 references for ABIN389309

  4. Human Polyclonal Ataxin 1 Primary Antibody for IF, ELISA - ABIN1531488 : Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... in Nature 2003 (PubMed)

More Antibodies against Ataxin 1 Interaction Partners

Fruit Fly (Drosophila melanogaster) Ataxin 1 (ATXN1) interaction partners

  1. Ataxin-1 induces intranuclear accumulation of dAtx2/hAtaxin-2 in both Drosophila and SCA1 postmortem neurons

  2. mutant ataxin-1 and huntingtin (show HTT Antibodies) induce developmental and late-onset neuronal pathologies in Drosophila models

Human Ataxin 1 (ATXN1) interaction partners

  1. This study reports the results of molecular dynamics simulations of AXH monomer of Ataxin-1.

  2. Systematic replacement of each lysine residue in the AXH domain revealed that the lysine at 589 (K589) of ATXN1 is essential for its ubiquitylation by UbcH6 (show UBE2E1 Antibodies).

  3. Results show that two SNPs in ATXN1 gene have a founder effect of the same repeat carrying allele as in the general Indian population suggesting that that Spinocerebellar ataxia (show USP14 Antibodies) type 1 disease onset is significantly delayed when transmission is maternal.

  4. this work provides the structural and molecular basis of the interaction between RBM17 (show RBM17 Antibodies) and the phosphorylated form of ATXN1.

  5. Partner recognition of the AXH domain of the transcriptional co-regulator ataxin-1 is fine-tuned by a subtle balance between self- and hetero-associations.

  6. We measured cerebellar neurochemical alterations in a knock-in mouse model of spinocerebellar ataxia (show USP14 Antibodies) type 1, a hereditary movement disorder, using ultra-high field magnetic resonance spectroscopy (MRS).

  7. Data indicate that the alternative ataxin-1 (ATXN1) protein is constitutively co-expressed and interacts with ATXN1.

  8. SCA 1 was the most frequent occurring type of SCA identified in the Autosomal dominant hereditary ataxia (show USP14 Antibodies) in Sri (show SRI Antibodies) Lanka.

  9. Results show variation in ATXN1 is implicated in disordered gambling

  10. conformational heterogeneity of the AXH domain of ataxin-1

Mouse (Murine) Ataxin 1 (ATXN1) interaction partners

  1. The results of this study found that upregulation of cholecystokinin (Cck (show CCK Antibodies)) and subsequent interaction with the Cck1 (show CCL28 Antibodies) receptor likely underlies the lack of progressive Purkinje cell pathology in Pcp2-ATXN1[30Q]D776 mice.

  2. Mutant ATXN1 forms oligomers whose levels correlate with disease progression in the Atxn1154Q/+ mice.

  3. The study showed that Sca1(+)Lin(-) bone marrow contains an endodermal precursor population of cells that differentiates into hepatocytes.

  4. HMGB1 (show HMGB1 Antibodies) facilitates repair of mitochondrial DNA damage of mutant ataxin-1 knock-in mice.

  5. The RNA-binding protein PUMILIO1 (PUM1 (show PUM1 Antibodies)) not only directly regulates ATAXIN1 but also plays an unexpectedly important role in neuronal function. Loss of Pum1 (show PUM1 Antibodies) caused progressive motor dysfunction and SCA1-like neurodegeneration with motor impairment, primarily by increasing Ataxin1 levels.

  6. study found a new function of ataxin-1: the modulation of Pp2a (show PPP2R2B Antibodies) activity and the regulation of its holoenzyme composition, with the polyglutamine mutation within Atxn1 altering this function in the spinocerebellar ataxia (show USP14 Antibodies) type 1 mouse cerebellum before disease onset

  7. Delivery of either ataxin-1-like (show ATXN1L Antibodies) viral vectors to Spinocerebellar Ataxia (show USP14 Antibodies) Type 1 mice cerebella resulted in widespread cerebellar Purkinje cell transduction

  8. downregulation of several components of the RAS-MAPK (show MAPK1 Antibodies)-MSK1 (show RPS6KA5 Antibodies) pathway decreases ATXN1 levels and suppresses neurodegeneration in mice

  9. we show that ATXN1 reduces histone acetylation, a post-translational modification of histones associated with enhanced transcription, and represses histone acetyl transferase (show HAT1 Antibodies)-mediated transcription.

  10. Loss of ATXN1, Atxn1L (show ATXN1L Antibodies) and CIC (show CIC Antibodies) is associated with hydrocephalus, omphalocele, and lung alveolarization defects.

Ataxin 1 (ATXN1) Antigen Profile

Protein Summary

The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. The function of the ataxins is not known. This locus has been mapped to chromosome 6, and it has been determined that the diseased allele contains 41-81 CAG repeats, compared to 6-39 in the normal allele, and is associated with spinocerebellar ataxia type 1 (SCA1). At least two transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with anti-Ataxin 1 (ATXN1) Antibodies

  • ataxin 1 (ATXN1) antibody
  • ataxin 1b (atxn1b) antibody
  • Ataxin 1 (Atx-1) antibody
  • ataxin 1 (Atxn1) antibody
  • ataxin 1-like (ATXN1L) antibody
  • 2900016G23Rik antibody
  • ataxin 1b antibody
  • Atx1 antibody
  • atxn1 antibody
  • C85907 antibody
  • CG4547 antibody
  • D6S504E antibody
  • dAtx-1 antibody
  • dAtx1 antibody
  • Dmel\\CG4547 antibody
  • ENSMUSG00000074917 antibody
  • Gm10786 antibody
  • sca1 antibody

Protein level used designations for anti-Ataxin 1 (ATXN1) Antibodies

ataxin 1 , spinocerebellar ataxia type 1 , Ataxin1 , Atx-1-PB , CG4547-PB , ataxin-1 , ataxin-1-like , spinocerebellar ataxia type 1 protein , spinocerebellar ataxia 1 homolog , spinocerebellar ataxia 1 , spinocerebellar ataxia type 1 protein homolog , spinocerebellar ataxia type 1 protien

GENE ID SPECIES
100065748 Equus caballus
493678 Felis catus
565841 Danio rerio
747421 Pan troglodytes
31624 Drosophila melanogaster
100025666 Monodelphis domestica
100402564 Callithrix jacchus
100437511 Pongo abelii
100467930 Ailuropoda melanoleuca
100588152 Nomascus leucogenys
6310 Homo sapiens
20238 Mus musculus
25049 Rattus norvegicus
488232 Canis lupus familiaris
100154571 Sus scrofa
616399 Bos taurus
100719683 Cavia porcellus
420843 Gallus gallus
101113284 Ovis aries
489725 Canis lupus familiaris
Selected quality suppliers for anti-Ataxin 1 (ATXN1) Antibodies
Did you look for something else?