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anti-BCL2-Associated Athanogene 3 (BAG3) Antibodies

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. Additionally we are shipping BAG3 Proteins (14) and BAG3 Kits (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BAG3 9531 O95817
BAG3 29810 Q9JLV1
BAG3 293524  
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Top anti-BAG3 Antibodies at antibodies-online.com

Showing 10 out of 93 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-BAG3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HT1080 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-Bag3 antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue Anti-Bag3 antibody, Western blotting Lane 1: MCF-7 Cell Lysate Lane 2: JURKAT Cell Lysate Lane 3: A549 Cell Lysate Lane 4: HELA Cell Lysate Lane 5: COLO320 Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- Bag3 Picoband antibody, IHC(P) IHC(P): Human Lung Cancer Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: MCF-7 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated ISt, IHC (p), WB WB Image BAG3 antibody detects BAG3 protein by Western blot analysis. A. 30 µg K562 whole cell lysate/extract 7.5 % SDS-PAGE BAG3 antibody , dilution: 1:1000 IHC-P Image Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using BAG3, antibody at 1:100 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Goat Un-conjugated EIA, IHC (p), WB Immunohistochemistry Image: Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) Immunohistochemistry Image: Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (89.36 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Goat Un-conjugated IHC (p), ELISA, WB Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details

BAG3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-BAG3 Antibodies

  1. Human Polyclonal BAG3 Primary Antibody for IHC, ELISA - ABIN1452054 : Lee, Takahashi, Yasuhara, Inazawa, Kamada, Tsujimoto: Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell death. in Oncogene 2000 (PubMed)
    Show all 2 references for ABIN1452054

  2. Human Polyclonal BAG3 Primary Antibody for ELISA, WB - ABIN184770 : Doong, Price, Kim, Gasbarre, Probst, Liotta, Blanchette, Rizzo, Kohn: CAIR-1/BAG-3 forms an EGF-regulated ternary complex with phospholipase C-gamma and Hsp70/Hsc70. in Oncogene 2000 (PubMed)

  3. Human Polyclonal BAG3 Primary Antibody for ELISA, WB - ABIN564108 : Youn, Lee, Lim, Yoon, Lim, Jung, Yeum, Park, Youn, Lee, Lee, Ikawa, Okabe, Tsujimoto, Lee: Bis deficiency results in early lethality with metabolic deterioration and involution of spleen and thymus. in American journal of physiology. Endocrinology and metabolism 2008 (PubMed)

  4. Cow (Bovine) Polyclonal BAG3 Primary Antibody for WB - ABIN2783302 : Franceschelli, Rosati, Lerose, De Nicola, Turco, Pascale: Bag3 gene expression is regulated by heat shock factor 1. in Journal of cellular physiology 2008 (PubMed)

More Antibodies against BAG3 Interaction Partners

Zebrafish BCL2-Associated Athanogene 3 (BAG3) interaction partners

  1. findings showed that the P209L mutation causes BAG3 to aggregate; proposed that the gradual loss of available BAG3(wt) and BAG3(P209L) proteins results in insufficiency leading to myofibrillar disintegration

Human BCL2-Associated Athanogene 3 (BAG3) interaction partners

  1. Bis expression was higher in squamous cell carcinoma than in adenocarcinoma in Lung Cancer.

  2. Data show although no any significant differences between patient groups and lean subjects of proteins SYT4 (show SYT4 Antibodies), BAG3, APOA1 (show APOA1 Antibodies), and VAV3 (show VAV3 Antibodies), except for VGF (show VGF Antibodies) protein, there was a trend between the expression of these four genes and their protein levels.

  3. our findings suggest the existence of a so-far unrecognized quality control mechanism involving BAG3, HSPB8 (show HSPB8 Antibodies) and p62/SQSTM1 (show SQSTM1 Antibodies) for accurate remodelling of actin-based mitotic structures that guide spindle orientation.

  4. BAG3 promotes pancreatic ductal adenocarcinoma growth by activating stromal macrophages.

  5. BAG3-mediated miRNA let-7g and let-7i inhibit proliferation and enhance apoptosis of human esophageal carcinoma cells by targeting the drug transporter ABCC10 (show ABCC10 Antibodies) and modulates cisplatin resistance.

  6. This newly described ERa-mediated and estrogen response element (ERE)-independent non-canonical autophagy pathway, which involves the function of BAG3 and provides stress resistance in our model systems.

  7. BAG3 protein loci is involved in the pathophysiology of systolic heart failure.

  8. MiR (show MLXIP Antibodies)-143 enhanced the tumor suppressive effect of shikonin partly through the regulation of BAG3 in glioblastoma stem cells.

  9. The Hsp70 (show HSP70 Antibodies)-Bag3 interaction may be a promising, new target for anticancer therapy.

  10. BAG3 mutations should be considered even in cases with a mild phenotype or an adult onset

Mouse (Murine) BCL2-Associated Athanogene 3 (BAG3) interaction partners

  1. molecular association of MyHC (show MYH13 Antibodies) and BIS is necessary for MyHC (show MYH13 Antibodies) stabilization in skeletal muscle.

  2. BAG3 promotes pancreatic ductal adenocarcinoma growth by activating stromal macrophages.

  3. Bis is upregulated in astrocytes after hypoxia-ischemia; hypoxia-ischemia induces progressive cell death in the hippocampi of bis-positive mice, while hippocampal neurons are less vulnerable to hypoxia-ischemia in mice that lack Bis.

  4. Deletion of the bis gene results in a marked increase in the production of corticosterone that is associated with thymic atrophy.

  5. BAG3 and Hsc70 (show HSPA8 Antibodies) interact with actin capping protein (show TMOD4 Antibodies) CapZ (show CAPZA1 Antibodies) to maintain myofibrillar integrity under mechanical stress.

  6. Results indicate that Bis functions to mediate cellular regulation of the stem cell niche on the vascular compartment.

  7. BAG3 alters the interaction between HSP70 (show HSP70 Antibodies) and IKKgamma (show IKBKG Antibodies), increasing availability of IKKgamma (show IKBKG Antibodies) and protecting it from proteasome-dependent degradation; this, in turn, results in increased NF-kappaB (show NFKB1 Antibodies) activity and survival

  8. BAG3 is not required for muscle development, this co-chaperone appears to be critically important for maintenance of mature skeletal muscle.

  9. The absence of Bis has considerable influences on postnatal growth and survival, possibly due to a nutritional impairment.

BAG3 Antigen Profile

Protein Summary

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

Gene names and symbols associated with BAG3

  • BCL2-associated athanogene 3 (bag3-A) antibody
  • BCL2-associated athanogene 3 (bag3) antibody
  • BCL2-associated athanogene 3 (BAG3) antibody
  • BCL2-associated athanogene 3 (LOC100228262) antibody
  • BCL-2-associated athanogene 3 (BAG3) antibody
  • BCL2-associated athanogene 3 (Bag3) antibody
  • Bcl2-associated athanogene 3 (Bag3) antibody
  • BCL2-associated athanogene 3 (LOC100358030) antibody
  • AA407278 antibody
  • ATBAG3 antibody
  • BAG-3 antibody
  • BAG3 antibody
  • bag3-A antibody
  • BCL-2-associated athanogene 3 antibody
  • Bis antibody
  • CAIR-1 antibody
  • MFM6 antibody
  • mg638 antibody
  • MGC53113 antibody
  • T28J14.160 antibody
  • T28J14_160 antibody
  • zgc:100859 antibody

Protein level used designations for BAG3

BCL2-associated athanogene 3 , BAG family molecular chaperone regulator 3 , BAG family molecular chaperone regulator 3-like , BCL2-binding athanogene 3 , bcl-2-binding protein Bis , docking protein CAIR-1 , BAG-3 , Bcl-2-binding protein Bis , Bcl-2-interacting death suppressor , bcl-2-associated athanogene 3

GENE ID SPECIES
379174 Xenopus laevis
445139 Danio rerio
450778 Pan troglodytes
714420 Macaca mulatta
100145358 Xenopus (Silurana) tropicalis
100228262 Taeniopygia guttata
100481230 Ailuropoda melanoleuca
830613 Arabidopsis thaliana
9531 Homo sapiens
29810 Mus musculus
293524 Rattus norvegicus
486916 Canis lupus familiaris
782633 Bos taurus
423931 Gallus gallus
100156989 Sus scrofa
100358030 Oryctolagus cuniculus
Selected quality suppliers for anti-BAG3 (BAG3) Antibodies
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