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anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) Antibodies

CXCR4 encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. Additionally we are shipping CXCR4 Kits (26) and CXCR4 Proteins (14) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CXCR4 12767 P70658
CXCR4 60628  
CXCR4 7852 P61073
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Top anti-CXCR4 Antibodies at antibodies-online.com

Showing 10 out of 466 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC, WB WB Suggested Anti-CXCR4 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 721_B cell lysate Sample type: human microvascular endothelial cells (25ug)Primary Dilution: 1:1000Secondary Antibody: Goat anti-Rabbit-HRPSecondary Dilution: 1:5000Image Submitted by: Andreas Eisenreich Charite Universitatsmedizin Berlin 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rat FITC FACS 100 μL Log in to see 10 to 12 Days
$415.80
Details
Human Rabbit Un-conjugated EIA, IHC (fro), IP, WB 0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from K562 cells, using CXCR4 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of A549 cells, using CXCR4 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IP, IHC, WB Western blot analysis of CXCR4 with Hela cell lysate. 100 μg Log in to see 2 to 3 Days
$304.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of CXCR4 expression in lysate from Jurkat (Lane 1,2) and 3T3 (Lane 3) cells. 100 μg Log in to see 2 to 3 Days
$304.50
Details
Chimpanzee Mouse Un-conjugated FACS, IHC (fro), IF, IHC (p) 0.5 mg Log in to see 6 to 8 Days
$885.50
Details
Human Rabbit Un-conjugated EIA, IF, WB Immunohistochemistry of CXCR4Lo in HeLa cells with CXCR4Lo antibody at 2 μg/ml. Immunofluorescence of CXCR4-Lo in Hela cells with CXCR4-Lo Antibody  at 4 ug/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, IF, IP, WB Immunocytochemistry of CXCR4 in HeLa cells with AP30266PU-N CXCR4 antibody at 2 μg/ml. Western blot analysis of CXCR4 in HeLa whole cell lysate with AP30266PU-N CXCR4 antibody at 0.5 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of CXCR4 in HeLa total cell lysate with AP30267PU-N anti-CXCR4 (EL) at 1/1000 dilution. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details

CXCR4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CXCR4 Antibodies

  1. Human Polyclonal CXCR4 Primary Antibody for EIA, WB - ABIN499698 : Berson, Long, Doranz, Rucker, Jirik, Doms: A seven-transmembrane domain receptor involved in fusion and entry of T-cell-tropic human immunodeficiency virus type 1 strains. in Journal of virology 1996 (PubMed)
    Show all 4 references for ABIN499698

  2. Human Polyclonal CXCR4 Primary Antibody for EIA, IF - ABIN499700 : Dimitrov: How do viruses enter cells? The HIV coreceptors teach us a lesson of complexity. in Cell 1998 (PubMed)
    Show all 4 references for ABIN499700

  3. Human Monoclonal CXCR4 Primary Antibody for FACS - ABIN2853593 : Nimura, Zhang, Okuma, Tanaka, Sunakawa, Yamamoto, Tanaka: Cross-linking cell surface chemokine receptors leads to isolation, activation, and differentiation of monocytes into potent dendritic cells. in Experimental biology and medicine (Maywood, N.J.) 2006 (PubMed)
    Show all 4 references for ABIN2853593

  4. Human Polyclonal CXCR4 Primary Antibody for EIA, IF - ABIN499696 : Feng, Broder, Kennedy, Berger: HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. in Science (New York, N.Y.) 1996 (PubMed)
    Show all 4 references for ABIN499696

  5. Human Polyclonal CXCR4 Primary Antibody for EIA, IHC (fro) - ABIN492892 : Tran, Miller: Chemokine receptors: signposts to brain development and disease. in Nature reviews. Neuroscience 2003 (PubMed)
    Show all 3 references for ABIN492892

  6. Chimpanzee Monoclonal CXCR4 Primary Antibody for FACS, IHC (fro) - ABIN264477 : Endres, Clapham, Marsh, Ahuja, Turner, McKnight, Thomas, Stoebenau-Haggarty, Choe, Vance, Wells, Power, Sutterwala, Doms, Landau, Hoxie: CD4-independent infection by HIV-2 is mediated by fusin/CXCR4. in Cell 1997 (PubMed)
    Show all 3 references for ABIN264477

  7. Human Polyclonal CXCR4 Primary Antibody for IP, IHC - ABIN223559 : Miwa, Mizokami, Keller, Taichman, Zhang, Namiki: The bisphosphonate YM529 inhibits osteolytic and osteoblastic changes and CXCR-4-induced invasion in prostate cancer. in Cancer research 2005 (PubMed)

  8. Human Polyclonal CXCR4 Primary Antibody for IF, ELISA - ABIN1535575 : Federsppiel, Melhado, Duncan, Delaney, Schappert, Clark-Lewis, Jirik: Molecular cloning of the cDNA and chromosomal localization of the gene for a putative seven-transmembrane segment (7-TMS) receptor isolated from human spleen. in Genomics 1993 (PubMed)

  9. Human Polyclonal CXCR4 Primary Antibody for FACS, IHC - ABIN2779387 : Yoshitake, Fukui, Yamagishi, Sekikawa, Fujii, Tomita, Ichikawa, Imura, Hiraishi, Fujimori: Expression of SDF-1 alpha and nuclear CXCR4 predicts lymph node metastasis in colorectal cancer. in British journal of cancer 2008 (PubMed)

  10. Human Polyclonal CXCR4 Primary Antibody for WB - ABIN223599 : Tillmanns, Rota, Hosoda, Misao, Esposito, Gonzalez, Vitale, Parolin, Yasuzawa-Amano, Muraski, De Angelis, Lecapitaine, Siggins, Loredo, Bearzi, Bolli, Urbanek, Leri, Kajstura, Anversa: Formation of large coronary arteries by cardiac progenitor cells. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

More Antibodies against CXCR4 Interaction Partners

Medaka Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

  1. bilateral lineup in the trunk before PGC (show PGC Antibodies) migration colonizing gonadal areas is defective in PGCS expressing a missense mutation in chemokine receptor (show CCR1 Antibodies) gene cxcr4b

Mouse (Murine) Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

  1. crosstalk between astrocytic CXCL12 (show CXCL12 Antibodies) and microglial CXCR4 in the pathogenesis of neuropathic pain.

  2. Results from using a plasmid transient expression of shRNA antiCXR4 shown that CXCR4 plays a critical role in the initial stages of development of murine melanoma B16F10 melanoma.

  3. DPP-4 (show DPP4 Antibodies) inhibition may have direct protective effects on the post-myocardial infarction heart by inducing an antiapoptotic effect and inhibiting a decrease in vessel number through the SDF-1a/CXCR4-mediated STAT3 (show STAT3 Antibodies) signaling pathway.

  4. confirm a pivotal role of the SDF-1 (show CXCL12 Antibodies)/CXCR4/CXCR7 (show CXCR7 Antibodies) axis for chronic allograft vasculopathy development

  5. CXCR4 has an important role in endothelial progenitor cells migration at the ischemic site.

  6. CXCR4/CXCL12 (show CXCL12 Antibodies) signaling may control movement of epithelial progenitors from the dental stem cell niche.

  7. our present study provided evidence that SDF-1 (show CXCL12 Antibodies) mediated CSCs migration through CXCR4 and CXCR7 (show CXCR7 Antibodies) via MEK (show MDK Antibodies)/ERK (show EPHB2 Antibodies) and PI3K/Akt (show AKT1 Antibodies) pathway

  8. Endothelial CXCR4 is negatively regulated by miR (show MLXIP Antibodies)-139-5p, whose transcription is in turn induced by laminar flow and APLN (show APLN Antibodies)/APLNR (show APLNR Antibodies) signalling.

  9. CXCR4 signaling has a role in radiation-induced lung damage that promotes breast cancer lung-metastasis

  10. Splenic TFF2 (show TFF2 Antibodies), a secreted anti-inflammatory peptide, is released by vagally modulated memory T cells to suppress the expansion of myeloid-derived suppressor cells through CXCR4.

Human Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

  1. Using Bioluminescence Resonance Energy Transfer and luciferase-complementation based methods the study show that US22 expression exhibits negative effects on CXCR4 signaling and constitutive surface expression in HEK293T cells.

  2. miR (show MLXIP Antibodies)-204-5p may function as an inhibitory RNA molecule in oral squamous cell carcinoma by targeting CXCR4.

  3. From our data we conclude that targeting of CXCR4 and FAK (show PTK2 Antibodies) may overcome ABCB1 (show ABCB1 Antibodies) and ABCC1 (show ABCC1 Antibodies)-dependent doxorubicin resistance in non-small cell lung carcinoma cells

  4. In GNC analysis, SNAI2 (show SNAI2 Antibodies) mRNA gene but not ITGA5 (show ITGA5 Antibodies), RGS2 (show RGS2 Antibodies) and PLEK2 (show PLEK2 Antibodies) was dependent on the signaling pathway of CXCR4.

  5. The CXCR4 genotype C>T of rs2228014 appeared to correlate with acute myeloid leukemia (show BCL11A Antibodies) risk, but played no role in leukemia cells invading the bloodstream.

  6. High CXCR4 expression in primary breast tumors (PTs (show PTS Antibodies)) was found to be associated with luminal A type tumor, suggesting more favorable outcome. In contrast, CCR7 (show CCR7 Antibodies) and FOXP3 (show FOXP3 Antibodies) expressions in PTs (show PTS Antibodies) represented luminal B tumors, pointing to more aggressive tumor behavior. Maspin (show SERPINB5 Antibodies) expression did not differ between luminal types.

  7. Exhibiting similar power of significance compared to CXCR3 (show CXCR3 Antibodies), CXCR4 expression also served as a predictor for clinical outcome in chronic lymphocytic leukemia patients.

  8. Exposure of CD133+ cells isolated from cord blood to PMPs with 10 mug/ml concentration increased the expression of CXCR4 surface marker significantly.

  9. These results suggested that RTN3 (show RTN3 Antibodies) modulates primordial germ cell migration through interaction with, and regulation of, CXCR4.

  10. we observed time points where surface CXCR4 appeared fully occupied but MEDI3185 was not detectable in serum. These paradoxical results represented a type of assay interference, and by comparing pharmacokinetic, ADA (show ADA Antibodies) and total CXCR4 results, the most likely reason for the free CXCR4 results was the emergence of neutralizing anti-drug antibodies (ADA (show ADA Antibodies)).

Pig (Porcine) Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

  1. CXCR4 controls leukocyte mobilization after trauma.

  2. The new method has shown to be capable of promoting CSCs proliferation and differentiation into cardiomyocytes through activating the SDF-1 (show CXCL12 Antibodies)/CXCR4 axis, while inhibiting myocardial apoptosis , thereby enhancing myocardial regeneration.

  3. reports transmural and perivascular expression patterns of chemokines CCL2 (show CCL2 Antibodies) and CXCL2 (show CXCL2 Antibodies) and of chemokine (show CCL1 Antibodies) receptors CCR2 (show CCR2 Antibodies), CCR5 (show CCR5 Antibodies), and CXCR4 following coronary angioplasty

Xenopus laevis Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

Cow (Bovine) Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

  1. There is a potential link between follicular SDF1 (show CXCL12 Antibodies)/CXCR4 activation and the regulation of ovulation-related genes in cows and horses.

  2. The combination of low expression of CXCR4 and high expression of IL-10 (show IL10 Antibodies) might be closely concerned with some bias for the production of PI calves.

Rhesus Monkey Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

  1. The increased CXCR4 and CXCR7 (show CXCR7 Antibodies) expression resulted in increased SDF-1 (show CXCL12 Antibodies)-induced RF/6A cell migration and tube formation.

  2. The CXCR7 (show CXCR7 Antibodies)/CXCR4/CXCL12 (show CXCL12 Antibodies) axis plays an important role in the formation of CNV, and may become a novel target for the treatment of choroidal neovascularization-associated diseases.

  3. These findings suggest that FBLN5 (show FBLN5 Antibodies) may interfere with choroidal neovascularization by downregulating VEGF (show VEGFA Antibodies), CXCR4, and TGFB1 (show TGFB1 Antibodies) expression and inhibiting choroidl endothelial cell proliferation.

  4. Virus recovered from CA28 plasma (SHIV(CA28NP)) used both CCR5 (show CCR5 Antibodies) and CXCR4 for entry, but the virus recovered from lymph node (SHIV(CA28NL)) used CXCR4 almost exclusively

Zebrafish Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

  1. Arteries are formed by vein-derived endothelial tip cells, this process critically depends on chemokine receptor Cxcr4 function.

  2. SDF1a (show CXCL12 Antibodies) directly controls the migration of both leading and trailing edges of a tissue through the activation of two independent receptors, CXCR4b and CXCR7 (show CXCR7 Antibodies).

  3. Hoxb8a is induced by and cooperates with Wnt (show WNT2 Antibodies) signaling to up-regulate cxcr4b, and acts through multiple mechanisms to repress cxcr7b expression.

  4. Expression of Cxcr4 and Cxcl12 (show CXCL12 Antibodies) in radial glial cells of the adult zebrafish brain supports important roles for the Cxcl12 (show CXCL12 Antibodies)/Cxcr4 pair in brain development and functioning.

  5. show that inactivation of the estrogen receptor ESR1 (show ESR1 Antibodies) results in ectopic expression of cxcr4b throughout the primordium, whereas ESR1 (show ESR1 Antibodies) overexpression results in a reciprocal reduction in the domain of cxcr4b expression.

  6. Study suggest that the Cxcl12a-Cxcr4b ligand-receptor pair are involved in the migration of GnRH3 neurons in zebrafish, and are therefore crucial for the development of this system.

  7. A CXCR4-like chemokine receptor (show CCR1 Antibodies) is expressed by the migrating lateral line primordium cells. Both the formation and the innervation of this system depend on the SDF1 (show CXCL12 Antibodies)-CXCR4 system.

  8. Knocking down CXCR4 results in severe defects in primordial germ cell migration.

  9. SDF-1 (show CXCL12 Antibodies)/CXCR4 signaling is important for guiding retinal ganglion cell axons within the retina to the optic stalk to exit the retina.

  10. chemokine (show CCL1 Antibodies) signaling contributes to both the olfactory placode assembly and the olfactory sensory neurons axon pathfinding in zebrafish

CXCR4 Antigen Profile

Protein Summary

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with CXCR4

  • chemokine (C-X-C motif) receptor 4 (cxcr4) antibody
  • chemokine (C-X-C motif) receptor 4 (CXCR4) antibody
  • chemokine (C-X-C motif) receptor 4 (Cxcr4) antibody
  • chemokine (C-X-C motif) receptor 4 (cxcr4-b) antibody
  • chemokine (C-X-C motif), receptor 4b (cxcr4b) antibody
  • neuropeptide Y receptor type 3 (CXCR4) antibody
  • cb403 antibody
  • CD184 antibody
  • Cmkar4 antibody
  • CXC-R4 antibody
  • CXC-R4-B antibody
  • CXCR-4 antibody
  • CXCR-4-B antibody
  • CXCR4 antibody
  • D2S201E antibody
  • FB22 antibody
  • HM89 antibody
  • HSY3RR antibody
  • LAP3 antibody
  • LCR1 antibody
  • LESTR antibody
  • NPY3R antibody
  • NPYR antibody
  • NPYRL antibody
  • NPYY3R antibody
  • PB-CKR antibody
  • PBSF/SDF-1 antibody
  • Sdf1r antibody
  • WHIM antibody
  • xcxcr4 antibody
  • zgc:109863 antibody

Protein level used designations for CXCR4

C-X-C chemokine receptor type 4 , SDF-1 receptor , Stromal cell-derived factor 1 receptor , chemokine (C-X-C motif) receptor 4 , CXC-R4 , CXCR-4 , chemokine (C-X-C) receptor 4 , chemokine receptor 4 , fusin , leukocyte-derived seven transmembrane domain receptor , leukocyte-expressed seven-transmembrane-domain , pre-B-cell-derived chemokine receptor , stromal cell-derived factor 1 receptor , CXC chemokine receptor , LESTR , chemokine receptor (LCR1) , CD184 antigen , leukocyte-derived seven-transmembrane-domain receptor , lipopolysaccharide-associated protein 3 , neuropeptide Y receptor Y3 , seven transmembrane helix receptor , seven-transmembrane-segment receptor, spleen , C-X-C chemokine receptor type 4-B , SDF-1 receptor B , SDF-1 receptor-B , Stromal cell-derived factor 1 receptor-B , stromal cell-derived factor 1 receptor B , LCR1 , chemokine receptor CXCR4 , CXC chemokine receptor 4 , ody , odysseus

GENE ID SPECIES
100038176 Xenopus (Silurana) tropicalis
100049444 Oryzias latipes
100346189 Oryctolagus cuniculus
100451032 Pongo abelii
100604120 Nomascus leucogenys
12767 Mus musculus
60628 Rattus norvegicus
7852 Homo sapiens
396659 Sus scrofa
380373 Xenopus laevis
281736 Bos taurus
493676 Felis catus
483900 Canis lupus familiaris
707329 Macaca mulatta
395324 Gallus gallus
100126711 Papio anubis
450130 Pan troglodytes
114447 Danio rerio
443532 Ovis aries
Selected quality suppliers for anti-CXCR4 (CXCR4) Antibodies
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