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anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) Antibodies

CXCR4 encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. Additionally we are shipping CXCR4 Kits (26) and CXCR4 Proteins (14) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CXCR4 12767 P70658
CXCR4 60628  
CXCR4 7852 P61073
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Top anti-CXCR4 Antibodies at antibodies-online.com

Showing 10 out of 351 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC, WB WB Suggested Anti-CXCR4 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:... Sample type: human microvascular endothelial cells (25ug)Primary Dilut... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rat FITC FACS 100 μL Log in to see 10 to 12 Days
$404.25
Details
Human Rabbit Un-conjugated EIA, IHC (fro), IP, WB 0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from K562 cells, using CXCR4 Antibod... Immunofluorescence analysis of A549 cells, using CXCR4 Antibody. The p... 100 μg Log in to see 2 to 3 Days
$275.00
Details
Human Rabbit Un-conjugated IP, IHC, WB Western blot analysis of CXCR4 with Hela cell lysate. 100 μg Log in to see 2 to 3 Days
$304.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of CXCR4 expression in lysate from Jurkat (Lane ... 100 μg Log in to see 2 to 3 Days
$304.50
Details
Chimpanzee Mouse Un-conjugated FACS, IHC (fro), IF, IHC (p) 0.5 mg Log in to see 6 to 8 Days
$852.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of CXCR4 in HeLa total cell lysate with AP30267P... 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, IF, IP, WB Immunocytochemistry of CXCR4 in HeLa cells with AP30266PU-N CXCR4 anti... Western blot analysis of CXCR4 in HeLa whole cell lysate with AP30266P... 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, IF, WB Immunohistochemistry of CXCR4Lo in HeLa cells with CXCR4Lo antibody at... Immunofluorescence of CXCR4-Lo in Hela cells with CXCR4-Lo Antibody  a... 0.1 mg Log in to see 6 to 8 Days
$401.50
Details

CXCR4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Top referenced anti-CXCR4 Antibodies

  1. Human Polyclonal CXCR4 Primary Antibody for EIA, IF - ABIN499696 : Berson, Long, Doranz, Rucker, Jirik, Doms: A seven-transmembrane domain receptor involved in fusion and entry of T-cell-tropic human immunodeficiency virus type 1 strains. in Journal of virology 1996 (PubMed)
    Show all 4 references for ABIN499696

  2. Human Polyclonal CXCR4 Primary Antibody for EIA, IF - ABIN499700 : Dimitrov: How do viruses enter cells? The HIV coreceptors teach us a lesson of complexity. in Cell 1998 (PubMed)
    Show all 4 references for ABIN499700

  3. Human Monoclonal CXCR4 Primary Antibody for FACS - ABIN2853593 : Nimura, Zhang, Okuma, Tanaka, Sunakawa, Yamamoto, Tanaka: Cross-linking cell surface chemokine receptors leads to isolation, activation, and differentiation of monocytes into potent dendritic cells. in Experimental biology and medicine (Maywood, N.J.) 2006 (PubMed)
    Show all 4 references for ABIN2853593

  4. Human Polyclonal CXCR4 Primary Antibody for EIA, WB - ABIN499698 : Feng, Broder, Kennedy, Berger: HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. in Science (New York, N.Y.) 1996 (PubMed)
    Show all 4 references for ABIN499698

  5. Human Polyclonal CXCR4 Primary Antibody for EIA, IHC (fro) - ABIN492892 : Tran, Miller: Chemokine receptors: signposts to brain development and disease. in Nature reviews. Neuroscience 2003 (PubMed)
    Show all 3 references for ABIN492892

  6. Chimpanzee Monoclonal CXCR4 Primary Antibody for FACS, IHC (fro) - ABIN264477 : Endres, Clapham, Marsh, Ahuja, Turner, McKnight, Thomas, Stoebenau-Haggarty, Choe, Vance, Wells, Power, Sutterwala, Doms, Landau, Hoxie: CD4-independent infection by HIV-2 is mediated by fusin/CXCR4. in Cell 1997 (PubMed)
    Show all 3 references for ABIN264477

  7. Human Polyclonal CXCR4 Primary Antibody for IP, IHC - ABIN223559 : Miwa, Mizokami, Keller, Taichman, Zhang, Namiki: The bisphosphonate YM529 inhibits osteolytic and osteoblastic changes and CXCR-4-induced invasion in prostate cancer. in Cancer research 2005 (PubMed)

  8. Human Polyclonal CXCR4 Primary Antibody for IF, ELISA - ABIN1535575 : Federsppiel, Melhado, Duncan, Delaney, Schappert, Clark-Lewis, Jirik: Molecular cloning of the cDNA and chromosomal localization of the gene for a putative seven-transmembrane segment (7-TMS) receptor isolated from human spleen. in Genomics 1993 (PubMed)

  9. Human Polyclonal CXCR4 Primary Antibody for FACS, IHC - ABIN2779387 : Yoshitake, Fukui, Yamagishi, Sekikawa, Fujii, Tomita, Ichikawa, Imura, Hiraishi, Fujimori: Expression of SDF-1 alpha and nuclear CXCR4 predicts lymph node metastasis in colorectal cancer. in British journal of cancer 2008 (PubMed)

  10. Human Polyclonal CXCR4 Primary Antibody for WB - ABIN223599 : Tillmanns, Rota, Hosoda, Misao, Esposito, Gonzalez, Vitale, Parolin, Yasuzawa-Amano, Muraski, De Angelis, Lecapitaine, Siggins, Loredo, Bearzi, Bolli, Urbanek, Leri, Kajstura, Anversa: Formation of large coronary arteries by cardiac progenitor cells. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

More Antibodies against CXCR4 Interaction Partners

Medaka Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

  1. bilateral lineup in the trunk before PGC (show PGC Antibodies) migration colonizing gonadal areas is defective in PGCS expressing a missense mutation in chemokine receptor (show CCR1 Antibodies) gene cxcr4b

Mouse (Murine) Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

  1. CXCR4 signaling has a role in radiation-induced lung damage that promotes breast cancer lung-metastasis

  2. Splenic TFF2 (show TFF2 Antibodies), a secreted anti-inflammatory peptide, is released by vagally modulated memory T cells to suppress the expansion of myeloid-derived suppressor cells through CXCR4.

  3. CXCR4 inhibitor attenuates allergen-induced lung inflammation by down-regulating MMP-9 (show MMP9 Antibodies) and ERK1/2 (show MAPK1/3 Antibodies) expression.

  4. CXCR4 regulates the acquisition of an EMT (show ITK Antibodies)-like phenotype in extra-medullary myeloma. CXCR4 silencing leads to reduced tumor growth.

  5. Dimethyloxalylglycine up-regulates myocardial CXCR4 expression to improve cardiac function in myocardial infarction.

  6. The estradiol-CXCL12 (show CXCL12 Antibodies)/CXCR4 signaling pathway may be useful in determining treatments for endometrial disorders, and may be antagonized to block stem cell migration to endometriosis.

  7. results suggest a novel mechanism whereby the local activation of CCR2 (show CCR2 Antibodies) on monocytes in the bone marrow attenuates an anchoring signalling provided by CXCR4 expressed by the same cell and mobilizes the bone marrow monocyte to the blood stream

  8. Revealed comparable numbers of hair follicles (HFs) forming in knockout embryos compared to wild-type littermate controls, suggesting that neither dermal nor epithelial Cxcr4 expression is required for early HF morphogenesis.

  9. Both CXCR7 (show CXCR7 Antibodies) and Rac1 are required for extracellular signal-regulated kinases (ERK) 1 (show MAPK3 Antibodies)/2 activation and subsequent NPC (show NPC1 Antibodies) migration, indicating that CXCR7 (show CXCR7 Antibodies) could serve as a functional receptor in CXCL12 (show CXCL12 Antibodies)-mediated NPC (show NPC1 Antibodies) migration independent of CXCR4.

  10. VEGFR1 (show FLT1 Antibodies) signaling facilitates angiogenesis in ischemia by recruiting CXCR4+VEGFR1 (show FLT1 Antibodies)-expressing cells from bone marrow.

Human Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

  1. Blood fibrocytes are recruited during COPD (show ARCN1 Antibodies) exacerbations and related to mortality and low lung function. The CXCL12 (show CXCL12 Antibodies)/CXCR4 axis is involved in such fibrocyte recruitment.

  2. chemokine receptor CXCR4 is targeted by peptide Nef-M1, which inhibits tumor angiogenesis and epithelialtomesenchymal transition in colon and breast cancers

  3. Synovial SDF-1 (show CXCL12 Antibodies) correlated with disease activity, and its receptor CXCR4 was related to joint destruction in rheumatoid arthritis patients treated with golimumab.

  4. CXCR4 signaling has a role in radiation-induced lung damage that promotes breast cancer lung-metastasis

  5. there is an elevation in CXCR4 and a decrease in SSTR2A expression with increasing malignancy in gastroenteropancreatic neuroendocrine neoplasms

  6. CXCR4 siRNA prohibited SDF-1 (show CXCL12 Antibodies)-induced AKT (show AKT1 Antibodies) and ERK (show EPHB2 Antibodies) phosphorylation, at the same time, EMT (show ITK Antibodies) biomarker changes were not observed. The SDF-1 (show CXCL12 Antibodies)/CXCR4 axis triggers EMT (show ITK Antibodies), tumor cell invasion and proliferation via activation of PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) and ERK (show EPHB2 Antibodies) pathways.

  7. This study demonstrates that the effects of CXCR4 inhibition on blast suppression and immune cell function in the tumor microenvironment and chemotherapy with plerixafor represents an advanced therapeutic strategy of targeting the leukemic niche.

  8. In U87 glioma cells, C23 (show NCL Antibodies) plays a crucial role in activation of SDF-1 (show CXCL12 Antibodies)-induced ERK (show EPHB2 Antibodies) and PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) pathways via interacting with CXCR4. C23 (show NCL Antibodies) interacted with CXCR4 once U87 was exposed to SDF-1 (show CXCL12 Antibodies) treatment.

  9. Triggering of LLT1 (show CLEC2D Antibodies) supported B cell activation (show BLNK Antibodies), CD83 (show CD83 Antibodies) upregulation, and CXCR4 downregulation

  10. These results suggest that targeting the production of CXCR4 and blocking the CXCL12 (show CXCL12 Antibodies)-CXCR4 pathway might be effective strategies for treating NSCLCs harboring a specific type of EGFR (show EGFR Antibodies) mutation.

Pig (Porcine) Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

  1. CXCR4 controls leukocyte mobilization after trauma.

  2. The new method has shown to be capable of promoting CSCs proliferation and differentiation into cardiomyocytes through activating the SDF-1 (show CXCL12 Antibodies)/CXCR4 axis, while inhibiting myocardial apoptosis , thereby enhancing myocardial regeneration.

  3. reports transmural and perivascular expression patterns of chemokines CCL2 (show CCL2 Antibodies) and CXCL2 (show CXCL2 Antibodies) and of chemokine (show CCL1 Antibodies) receptors CCR2 (show CCR2 Antibodies), CCR5 (show CCR5 Antibodies), and CXCR4 following coronary angioplasty

Xenopus laevis Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

Cow (Bovine) Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

  1. There is a potential link between follicular SDF1 (show CXCL12 Antibodies)/CXCR4 activation and the regulation of ovulation-related genes in cows and horses.

  2. The combination of low expression of CXCR4 and high expression of IL-10 (show IL10 Antibodies) might be closely concerned with some bias for the production of PI calves.

Rhesus Monkey Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

  1. The increased CXCR4 and CXCR7 (show CXCR7 Antibodies) expression resulted in increased SDF-1 (show CXCL12 Antibodies)-induced RF/6A cell migration and tube formation.

  2. The CXCR7 (show CXCR7 Antibodies)/CXCR4/CXCL12 (show CXCL12 Antibodies) axis plays an important role in the formation of CNV, and may become a novel target for the treatment of choroidal neovascularization-associated diseases.

  3. These findings suggest that FBLN5 (show FBLN5 Antibodies) may interfere with choroidal neovascularization by downregulating VEGF (show VEGFA Antibodies), CXCR4, and TGFB1 (show TGFB1 Antibodies) expression and inhibiting choroidl endothelial cell proliferation.

  4. Virus recovered from CA28 plasma (SHIV(CA28NP)) used both CCR5 (show CCR5 Antibodies) and CXCR4 for entry, but the virus recovered from lymph node (SHIV(CA28NL)) used CXCR4 almost exclusively

Zebrafish Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

  1. Arteries are formed by vein-derived endothelial tip cells, this process critically depends on chemokine receptor Cxcr4 function.

  2. SDF1a (show CXCL12 Antibodies) directly controls the migration of both leading and trailing edges of a tissue through the activation of two independent receptors, CXCR4b and CXCR7 (show CXCR7 Antibodies).

  3. Hoxb8a is induced by and cooperates with Wnt (show WNT2 Antibodies) signaling to up-regulate cxcr4b, and acts through multiple mechanisms to repress cxcr7b expression.

  4. Expression of Cxcr4 and Cxcl12 (show CXCL12 Antibodies) in radial glial cells of the adult zebrafish brain supports important roles for the Cxcl12 (show CXCL12 Antibodies)/Cxcr4 pair in brain development and functioning.

  5. show that inactivation of the estrogen receptor ESR1 (show ESR1 Antibodies) results in ectopic expression of cxcr4b throughout the primordium, whereas ESR1 (show ESR1 Antibodies) overexpression results in a reciprocal reduction in the domain of cxcr4b expression.

  6. Study suggest that the Cxcl12a-Cxcr4b ligand-receptor pair are involved in the migration of GnRH3 neurons in zebrafish, and are therefore crucial for the development of this system.

  7. A CXCR4-like chemokine receptor (show CCR1 Antibodies) is expressed by the migrating lateral line primordium cells. Both the formation and the innervation of this system depend on the SDF1 (show CXCL12 Antibodies)-CXCR4 system.

  8. Knocking down CXCR4 results in severe defects in primordial germ cell migration.

  9. SDF-1 (show CXCL12 Antibodies)/CXCR4 signaling is important for guiding retinal ganglion cell axons within the retina to the optic stalk to exit the retina.

  10. chemokine (show CCL1 Antibodies) signaling contributes to both the olfactory placode assembly and the olfactory sensory neurons axon pathfinding in zebrafish

CXCR4 Antigen Profile

Protein Summary

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with CXCR4

  • chemokine (C-X-C motif) receptor 4 (cxcr4) antibody
  • chemokine (C-X-C motif) receptor 4 (CXCR4) antibody
  • chemokine (C-X-C motif) receptor 4 (Cxcr4) antibody
  • chemokine (C-X-C motif) receptor 4 (cxcr4-b) antibody
  • chemokine (C-X-C motif), receptor 4b (cxcr4b) antibody
  • neuropeptide Y receptor type 3 (CXCR4) antibody
  • cb403 antibody
  • CD184 antibody
  • Cmkar4 antibody
  • CXC-R4 antibody
  • CXC-R4-B antibody
  • CXCR-4 antibody
  • CXCR-4-B antibody
  • CXCR4 antibody
  • D2S201E antibody
  • FB22 antibody
  • HM89 antibody
  • HSY3RR antibody
  • LAP3 antibody
  • LCR1 antibody
  • LESTR antibody
  • NPY3R antibody
  • NPYR antibody
  • NPYRL antibody
  • NPYY3R antibody
  • PB-CKR antibody
  • PBSF/SDF-1 antibody
  • Sdf1r antibody
  • WHIM antibody
  • xcxcr4 antibody
  • zgc:109863 antibody

Protein level used designations for CXCR4

C-X-C chemokine receptor type 4 , SDF-1 receptor , Stromal cell-derived factor 1 receptor , chemokine (C-X-C motif) receptor 4 , CXC-R4 , CXCR-4 , chemokine (C-X-C) receptor 4 , chemokine receptor 4 , fusin , leukocyte-derived seven transmembrane domain receptor , leukocyte-expressed seven-transmembrane-domain , pre-B-cell-derived chemokine receptor , stromal cell-derived factor 1 receptor , CXC chemokine receptor , LESTR , chemokine receptor (LCR1) , CD184 antigen , leukocyte-derived seven-transmembrane-domain receptor , lipopolysaccharide-associated protein 3 , neuropeptide Y receptor Y3 , seven transmembrane helix receptor , seven-transmembrane-segment receptor, spleen , C-X-C chemokine receptor type 4-B , SDF-1 receptor B , SDF-1 receptor-B , Stromal cell-derived factor 1 receptor-B , stromal cell-derived factor 1 receptor B , LCR1 , chemokine receptor CXCR4 , CXC chemokine receptor 4 , ody , odysseus

GENE ID SPECIES
100038176 Xenopus (Silurana) tropicalis
100049444 Oryzias latipes
100346189 Oryctolagus cuniculus
100451032 Pongo abelii
100604120 Nomascus leucogenys
12767 Mus musculus
60628 Rattus norvegicus
7852 Homo sapiens
396659 Sus scrofa
380373 Xenopus laevis
281736 Bos taurus
493676 Felis catus
483900 Canis lupus familiaris
707329 Macaca mulatta
395324 Gallus gallus
100126711 Papio anubis
450130 Pan troglodytes
114447 Danio rerio
443532 Ovis aries
Selected quality suppliers for anti-CXCR4 (CXCR4) Antibodies
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