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CLDN10 encodes a member of the claudin family. Additionally we are shipping CLDN10 Kits (14) and CLDN10 Proteins (3) and many more products for this protein.
Showing 10 out of 62 products:
Human Polyclonal CLDN10 Primary Antibody for WB - ABIN2778039
Gonzualez-Mariscal, Betanzos, Nava, Jaramillo: Tight junction proteins. in Progress in biophysics and molecular biology 2002
Human Polyclonal CLDN10 Primary Antibody for WB - ABIN522511
Kammula, Mötter, Gorgels, Jonas, Hoffmann, Willbold: Brain transcriptome-wide screen for HIV-1 Nef protein interaction partners reveals various membrane-associated proteins. in PLoS ONE 2013
localization of Cldn3 (show CLDN3 Antibodies), Cldn7 (show CLDN7 Antibodies) and Cldn10 proteins in the different compartments of murine endometrium up to day 8.5 of pregnancy (dpc) as well as in human endometrium and first trimester decidua
An algorithm combining CLDN10, HMGA2, and LAMB3 (show LAMB3 Antibodies) transcripts was able to discriminate tumors from BTL (show CHIC2 Antibodies) samples (94% sensitivity and 96% specificity in validation set).
Expression of CLDN1 (show CLDN1 Antibodies) and CLDN10 was lower in invasive lepidic predominant adenocarcinoma than in lung adenocarcioma in situ. Overexpression of CLDN1 (show CLDN1 Antibodies) and CLDN10 indicates a favorable prognosis in some patients with lung adenocarcinoma.
Claudin 10 expression was down-regulated in gastric cancer.
In claudin-10b, the F66L mutant reduced cation selectivity, and the F66A mutant lost pore conductance
Claudin 10/18 are most commonly expressed in lung adenocarcinomas. Female patients and non-smokers express these claudins more commonly suggesting that they may play a part in the carcinogenesis of tobacco unrelated carcinoma.
Claudin 10 protein is highly expressed in hepatocellular carcinoma (HCC (show FAM126A Antibodies)) tissue and is closely related to angiogenesis. It could be a useful marker to predict poor prognosis of HCC (show FAM126A Antibodies) patients after hepatectomy.
CLDN10 is a novel biomarker for detecting ovarian cancer in the chicken, a suitable animal model for investigating the effect and function of CLDN in human ovarian cancer.
High Claudin-10 expression level is associated with recurrence of primary hepatocellular carcinoma
These findings showed that CLDN-10 is functionally involved in hepatocellular carcinoma invasion and is a potential target for hepatocellular carcinoma therapy.
These data identify claudin-10 as a key factor in control of cation selectivity and transport in the thick ascending limb, and deficiency in this pathway as a cause of nephrocalcinosis.
Claudin-10 is expressed at the variety of epithelial tissues in the coclea of inner ear including Organ of Corti, stria vascularis, Reissner's membrane, and spiral limbus.
alternative splicing of claudin-10 generates unique permselectivities and might contribute to the variable paracellular transport observed along the nephron
Claudin-10 exists in six alternatively spliced isoforms that exhibit distinct localization and function.
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The expression level of this gene is associated with recurrence of primary hepatocellular carcinoma. Six alternatively spliced transcript variants encoding different isoforms have been reported, but the transcript sequences of some variants are not determined.
, OSP-like protein
, claudin 10A
, claudin 10B