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The protein encoded by DPP4 is a homodimeric integral membrane gelatinase belonging to the serine protease family. Additionally we are shipping DPP4 Kits (87) and DPP4 Proteins (54) and many more products for this protein.
Showing 10 out of 617 products:
Human Monoclonal DPP4 Primary Antibody for FACS, IHC (p) - ABIN1106157
Kotani, Asada, Aratake, Umeki, Yamamoto, Tokudome, Hirai, Kuma, Konoe, Araki: Diagnostic usefulness of dipeptidyl aminopeptidase IV monoclonal antibody in paraffin-embedded thyroid follicular tumours. in The Journal of pathology 1993
Show all 4 references for ABIN1106157
Mouse (Murine) Monoclonal DPP4 Primary Antibody for FACS - ABIN320274
Cinar, Senol, Ozen: Immunohistochemical study on distribution of endocrine cells in gastrointestinal tract of flower fish (Pseudophoxinus antalyae). in World journal of gastroenterology : WJG 2006
Show all 3 references for ABIN320274
Human Polyclonal DPP4 Primary Antibody for IHC (p) - ABIN188903
Amatya, Takeshima, Kushitani, Yamada, Morimoto, Inai: Overexpression of CD26/DPPIV in mesothelioma tissue and mesothelioma cell lines. in Oncology reports 2011
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Dog (Canine) Polyclonal DPP4 Primary Antibody for EIA, WB - ABIN374762
Pei, Li, von Geldern, Longenecker, Pireh, Stewart, Backes, Lai, Lubben, Ballaron, Beno, Kempf-Grote, Sham, Trevillyan: Discovery and structure-activity relationships of piperidinone- and piperidine-constrained phenethylamines as novel, potent, and selective dipeptidyl peptidase IV inhibitors. in Journal of medicinal chemistry 2007
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Human Monoclonal DPP4 Primary Antibody for FACS, IF - ABIN2452961
Zhao, Li, Wohlford-Lenane, Agnihothram, Fett, Zhao, Gale, Baric, Enjuanes, Gallagher, McCray, Perlman: Rapid generation of a mouse model for Middle East respiratory syndrome. in Proceedings of the National Academy of Sciences of the United States of America 2014
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Mouse (Murine) Monoclonal DPP4 Primary Antibody for EIA, FACS - ABIN120302
Vivier, Marguet, Naquet, Bonicel, Black, Li, Bernard, Gorvel, Pierres: Evidence that thymocyte-activating molecule is mouse CD26 (dipeptidyl peptidase IV). in Journal of immunology (Baltimore, Md. : 1950) 1991
Human Monoclonal DPP4 Primary Antibody for FACS - ABIN118573
Berg, James, Alvarez-Iglesias, Glennie, Lechler, Marelli-Berg: Functional consequences of noncognate interactions between CD4+ memory T lymphocytes and the endothelium. in Journal of immunology (Baltimore, Md. : 1950) 2002
NPY is efficiently cleaved by FAP indicating a potential function for FAP in neuropeptide regulation within liver and cancer biology.
degradomic study highlights cell-contextual proteolysis by FAPalpha with distinct positional profiles. Generally, our findings link FAPalpha to key aspects of CAF (show KAT2B Antibodies) biology and attribute an important role in tumor-stroma interaction to FAPalpha
Results identified heart expression of DPP4 to be coordinated with a gene expression signature characteristic for whole blood proliferation, potentially impacting peripheral stem cell mobilization.
decreased T-cell expression and lower plasma levels in Indian patients with Post Kala-azar Dermal Leishmaniasis
The effect of the DPP-4 inhibitor alogliptin on HbA1c.
Data suggest that a DNA vaccine targeting human fibroblast activation protein alpha (show FAP Antibodies) (FAPalpha) may be an attractive and effective cancer immunotherapy strategy.
In this study, we show for the first time the expression of FAP in activated fibroblasts after MI and its activation by TGFbeta1 (show TGFB1 Antibodies). Effects of FAP on fibroblast migration and gelatinolytic activity indicate a potential role in cardiac wound healing
Lack of DPP4 expression may be the primary cause of limited MERS-CoV replication in the human upper respiratory tract and hence restrict transmission.
FAP is expressed by activated, collagen-synthesizing fibroblasts, but not by inactive fibroblasts or fully differentiated myofibroblasts and non-fibroblast cells in the infarct.
Loss of DPP4 is associated with Multi-Organ Damage in Human Dipeptidyl Peptidase 4 Transgenic Mice Infected with Middle East Respiratory Syndrome-Coronavirus.
Results describe a proline-rich cytokine from neurosecretory granules that represents a new natural substrate for Dipeptidyl Peptidase IV (DPPIV).
Data demonstrate that dipeptidyl peptidase II (show DPP7 Antibodies) can form a complex with adenosine deaminase (show ADA Antibodies), but with one order of magnitude higher dissociation constant than that of DPPIV.
This study shows that porcine DPP-IV is generally inhibited with greater potency by protein-derived peptides than is the human enzyme
DPP-IV from porcine kidney cortex was characterized.
Neutral endopeptidase 24.11 (show MME Antibodies) and DPP-IV is superior to DPP-IV inhibition alone in preserving intact GLP-1 (show GCG Antibodies), which implies possibility that the combination has therapeutic potential.
Results describe the distribution of dipeptidyl peptidase IV-like activity enzymes in porcine tissue sections by RT-PCR.
Data suggest that pharmacological stimulation of serotonin 5Ht1b (show HTR1B Antibodies) receptor enhances up-regulation of plasma Glp1 (glucagon-like peptide 1 (show GCG Antibodies)) induced by Dpp4 (dipeptidylpeptidase 4) inhibition independently of feeding and also improves glucose tolerance.
Young euglycemic Dpp4 KO mice showed a cardioprotective response after transverse aortic constriction or doxorubicin administration, with reduced fibrosis; however, cardiac mRNA analysis revealed increased expression of inflammation-related transcripts.
Dipeptidyl peptidase-4 inhibition by gemigliptin exerts a preventative effect on the proliferation and migration of VSMCs via Nrf2 (show NFE2L2 Antibodies).
The present study reveals the activation of autophagy to mediate the anti-diabetic effect of GLP-1 (show GCG Antibodies).
These results indicate that DPP-4 inhibitors pleiotropically exert a direct renoprotective effect, and may serve as an additional therapeutic strategy to protect proximal tubular cells against proteinuria in patients with diabetic nephropathy.
DPP-4 and integrin beta1 interactions regulate key endothelial cell signal transduction in both physiological and pathological conditions including endothelial mesenchymal transformation.
sDPP-4 enhances inflammatory actions via TLR pathway, while DPP-4 inhibition with either an enzymatic or binding inhibitor has anti-inflammatory effects.
DPP4i restores cardiac remodeling and apoptosis caused by the pathological decline in circulating GLP-1 in response to pressure overload. EPAC1 is essential for cardiomyocyte survival via the cAMP/Rap1 activation independently of PKA.
Combination of DPP-4 inhibitor and PPARgamma (show PPARG Antibodies) agonist exerts protective effects on pancreatic beta-cells in diabetic db/db (show LEPR Antibodies) mice through the augmentation of IRS-2 (show IRS2 Antibodies) expression
DPP4 inhibiton appeared to suppress neointimal formation by inhibiting inflammation, independently of its effects on glucose or cholesterol metabolism in atherogenic LDL receptor (show LDLR Antibodies) KO mice.
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis.
dipeptidyl peptidase 9
, dipeptidyl-peptidase 4
, dipeptidyl-peptidase IV
, dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2)
, dipeptidylpeptidase IV
, dipeptidyl peptidase 4
, DPP IV
, T-cell activation antigen CD26
, adenosine deaminase complexing protein 2
, dipeptidyl peptidase IV
, dipeptidylpeptidase 4
, dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2)
, activation molecule 3
, adenosine deaminase complexing protein
, dipeptidyl-peptidase iv
, thymocyte-activating molecule
, GP110 glycoprotein
, bile canaliculus domain-specific membrane glycoprotein
, 170 kDa melanoma membrane-bound gelatinase
, integral membrane serine protease