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DRD4 encodes the D4 subtype of the dopamine receptor. Additionally we are shipping DRD4 Kits (25) and DRD4 Proteins (5) and many more products for this protein.
Showing 10 out of 127 products:
Human Monoclonal DRD4 Primary Antibody for WB - ABIN1882235
Zeng, Ye, Lu, Chua, Tan, Zhong: Chiral Brønsted acid catalyzed enantioselective addition of alpha-isocyanoacetamides to aldehydes. in Organic letters 2010
Show all 4 references for ABIN1882235
Human Monoclonal DRD4 Primary Antibody for WB - ABIN1882234
Lai, Zhu, Huo, Sun, Yu, Wang, Chai, Li: Association study of polymorphisms in the promoter region of DRD4 with schizophrenia, depression, and heroin addiction. in Brain research 2010
Show all 4 references for ABIN1882234
Mouse (Murine) Polyclonal DRD4 Primary Antibody for WB - ABIN1742092
Sidhu, Niznik: Coupling of dopamine receptor subtypes to multiple and diverse G proteins. in International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2000
Show all 4 references for ABIN1742092
Human Polyclonal DRD4 Primary Antibody for ICC, IF - ABIN314548
Unland, Kerl, Schlosser, Farwick, Plagemann, Lechtape, Clifford, Kreth, Gerss, Mühlisch, Richter, Hasselblatt, Frühwald: Epigenetic repression of the dopamine receptor D4 in pediatric tumors of the central nervous system. in Journal of neuro-oncology 2014
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Human Polyclonal DRD4 Primary Antibody for DB, EIA - ABIN492914
Farooqui, Brock, Hamdi, Prasad: Antibodies against synthetic peptides predicted from the nucleotide sequence of D2 receptor recognize native dopamine receptor protein in rat striatum. in Journal of neurochemistry 1991
Show all 3 references for ABIN492914
Human Polyclonal DRD4 Primary Antibody for IF, ELISA - ABIN1535585
Van Tol, Wu, Guan, Ohara, Bunzow, Civelli, Kennedy, Seeman, Niznik, Jovanovic: Multiple dopamine D4 receptor variants in the human population. in Nature 1992
Show all 2 references for ABIN1535585
Human Polyclonal DRD4 Primary Antibody for ELISA, WB - ABIN185712
Li, Sham, Owen, He: Meta-analysis shows significant association between dopamine system genes and attention deficit hyperactivity disorder (ADHD). in Human molecular genetics 2006
Human Polyclonal DRD4 Primary Antibody for EIA, WB - ABIN453626
Livingstone, Strange, Naylor: Molecular modelling of D2-like dopamine receptors. in The Biochemical journal 1992
Human Polyclonal DRD4 Primary Antibody for FACS, IHC (p) - ABIN652706
Ma, Thapa, Morris, Michalakis, Biel, Frank, Bebak, Ding: Loss of cone cyclic nucleotide-gated channel leads to alterations in light response modulating system and cellular stress response pathways: a gene expression profiling study. in Human molecular genetics 2013
Authors examined the possible association between DRD4 allelic variation and three measures of juvenile behavior. Five different DRD4 alleles (5R, 5.5R, 6R, 6.5R, and 7R) were identified in the subject population.
p44 (show GTF2H2 Antibodies)/42 MAPK (show MAPK1 Antibodies) phosphorylation, the signaling pathway which is often regulated by beta-arrestins is not influenced by KLHL12 (show KLHL12 Antibodies), but seems to be exclusively mediated by Galphai protein upon dopamine D4 receptor stimulation.
The results indicate that epigenetic regulation of the DRD4 gene in the form of increased methylation is associated with the cognitive/attentional deficits in ADHD.
DRD4 antagonist has an antimelanogenic effect that is related to downregulation of MITF (show MITF Antibodies) transcription through the activation of the ERK (show EPHB2 Antibodies)
DRD4 7-repeat carriers with ADHD showed the least striatal activation during reward anticipation when exposed to high maternal warmth, but the most when exposed to low warmth.
DRD4 gene expression reduction in breast cancer patients after spiritual intervention
Polymorphisms of the DRD4 gene appear to be associated with SSRI treatment response in Chinese MDD patients.
Findings provide evidence of an epistatic interaction between polymorphisms acting within the dopamine system (specifically upon DRD4 and COMT (show COMT Antibodies) activity) and likelihood of comorbid substance abuse in women with bulimia-spectrum eating disturbances
Community disadvantage interacted with parental DRD4 status to predict low levels of protective parenting. Protective parenting, in turn, interacted with youth DRD4 status to forecast increases in youth's planful future orientations, a proximal influence on changes in risk behavior.
DRD4 and SLC6A3 (show SLC6A3 Antibodies) gene polymorphisms may have a role in food intake and nutritional status in children in early stages of development
There may be a specific molecular pathway by which the DRD4-521T genotype alters ACC electrophysiology and thereby predicts the level of problematic substance use in undergraduates.
The G-protein coupled receptor, DRD4, requires ARR1 and ARR4 for desensitization and internalization.
This study demonstrated that dopamine D4 receptor gene has an important role in increased exploratory and anxiolytic behavior only in males and these behaviors were positively correlated with increased alcohol consumption.
Contrast sensitivity is reduced in Drd4-/- mice.
dopaminergic modulation of early long-term potentiation in stratum oriens occurs through NMDA receptors containing NR2B (show GRIN2B Antibodies) subunits via D4Rs
Data demonstrate that stimulating the dopamine Dreceptor is essential in maintaining the normal rhythmic production of adenylyl cyclase 1 (show ADCY1 Antibodies) from transcript to enzyme activity.
This study demonistrated that the dopamine D4 receptor is the role of attention.
The result of this study demonistrated that the dopamine drd4 receptor appears to be important for specific exploration.
no connection between analysed polymorphism of genes: DRD2 (show DRD2 Antibodies), DRD3 (show DRD3 Antibodies), DRD4, DAT (show SLC6A3 Antibodies), COMT (show COMT Antibodies) and schizophrenia was stated.
This result suggests an effect of 5-HTTLPR (show SLC6A4 Antibodies) on externalizing behavior in the presence of DRD4 7r but no effect in its absence.
D4R signaling is essential for the expression of juvenile hyperactivity and impaired behavioral inhibition, relevant features present in this attention deficit disorder-like mouse model.
This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats\; the sequence shown contains four repeats.
dopamine D4b receptor
, dopamine receptor D4
, D(2C) dopamine receptor
, D(4) dopamine receptor
, dopamine D4 receptor
, seven transmembrane helix receptor
, d(2C) dopamine receptor
, dopamine receptor 4