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anti-Duffy Blood Group, Chemokine Receptor (DARC) Antibodies

The protein encoded by DARC is a glycosylated membrane protein and a non-specific receptor for several chemokines. Additionally we are shipping DARC Proteins (6) and DARC Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DARC 2532 Q16570
DARC 689105  
DARC 13349 Q9QUI6
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Top anti-DARC Antibodies at antibodies-online.com

Showing 10 out of 87 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, ELISA Immunofluorescence analysis of A549 cells, using CD234 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN185480 (0.1µg/ml) staining of human liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN185480 (3µg/ml) staining of paraffin embedded human kidney. Microwaved antigen retrieval with citrate buffer pH 6, HRP-staining. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Goat Un-conjugated FACS, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of DARC in mouse brain tissue with DARC antibody at 2.5 μg/ml. Western blot analysis of DARC in mouse brain tissue lysate with AP30273PU-N DARC antibody at (A) 0.5, (B) 1 and (C) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of DARC in human brain tissue with DARC antibody at 5 μg/ml. Western blot analysis of DARC in PC-3 cell lysate with AP30274PU-N DARC antibody at (A) 0.5, (B) 1 and (C) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB DARC Antibody (N-term) (ABIN1881251) western blot analysis in CEM cell line lysates (35 µg/lane). This demonstrates the DARC antibody detected the DARC protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IC, IF, WB Western blot analysis of CD234 expression in HeLa (A), K562 (B), Raw264.7 (C), PC12 (D) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 15 to 19 Days
$455.07
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 15 to 19 Days
$455.07
Details

DARC Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
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Rat (Rattus)


Mouse (Murine)
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Top referenced anti-DARC Antibodies

  1. Human Polyclonal DARC Primary Antibody for WB - ABIN1881251 : Silva, Blanton, Parrado, Melo, Morato, Reis, Dias, Castro, Vasconcelos, Goddard, Barreto, Reis, Teixeira: Dengue hemorrhagic fever is associated with polymorphisms in JAK1. in European journal of human genetics : EJHG 2010 (PubMed)
    Show all 4 references for ABIN1881251

  2. Human Polyclonal DARC Primary Antibody for EIA, IHC (p) - ABIN499710 : Gardner, Patterson, Ashton, Stone, Middleton: The human Duffy antigen binds selected inflammatory but not homeostatic chemokines. in Biochemical and biophysical research communications 2004 (PubMed)
    Show all 3 references for ABIN499710

  3. Human Polyclonal DARC Primary Antibody for EIA, IHC (p) - ABIN499712 : Chaudhuri, Polyakova, Zbrzezna, Williams, Gulati, Pogo: Cloning of glycoprotein D cDNA, which encodes the major subunit of the Duffy blood group system and the receptor for the Plasmodium vivax malaria parasite. in Proceedings of the National Academy of Sciences of the United States of America 1993 (PubMed)
    Show all 3 references for ABIN499712

  4. Human Polyclonal DARC Primary Antibody for FACS, IHC (p) - ABIN374609 : Brühl, Vielhauer, Weiss, Mack, Schlöndorff, Segerer: Expression of DARC, CXCR3 and CCR5 in giant cell arteritis. in Rheumatology (Oxford, England) 2005 (PubMed)

  5. Human Polyclonal DARC Primary Antibody for IF, ELISA - ABIN1535586 : Iwamoto, Omi, Kajii, Ikemoto: Genomic organization of the glycoprotein D gene: Duffy blood group Fya/Fyb alloantigen system is associated with a polymorphism at the 44-amino acid residue. in Blood 1995 (PubMed)

More Antibodies against DARC Interaction Partners

Human Duffy Blood Group, Chemokine Receptor (DARC) interaction partners

  1. We showed that DARC expression is down-regulated in CRC (show CALR Antibodies) and associated with clinical pathological features and MVD (show MVD Antibodies) of CRC (show CALR Antibodies). DARC might be involved in tumorigenesis, progression, angiogenesis, and metastasis of CRC (show CALR Antibodies).

  2. DARC is required for Staphylococcus aureus-mediated lysis of human erythrocytes, and DARC overexpression is sufficient to render cells susceptible to toxin-mediated lysis.

  3. study demonstrates the association of SNP rs12075 from DARC gene with the levels of serum IL8 (show IL8 Antibodies)

  4. DARC levels are elevated in human keloid fibroblasts and might inhibit the secretion of CCL2 (show CCL2 Antibodies).

  5. Through molecular genotyping we also identified polymorphisms in RhCE (show RHCE Antibodies), Kell, Duffy, Colton, Lutheran and Scianna loci in donors and patients.

  6. Duffy blood group

  7. Isothermal titration calorimetry studies show these structures are part of a multi-step binding pathway, and individual point mutations of residues contacting DARC result in a complete loss of RBC (show CACNA1C Antibodies) binding by DBP (show GC Antibodies)-RII.

  8. DARC polymorphisms may influence the naturally acquired inhibitory anti-Duffy binding protein II (show ANXA4 Antibodies) immunity

  9. DARC facilitates CXCL1 (show CXCL1 Antibodies) inhibition of airway smooth muscle cell migration via modulation of the ERK-1 (show MAPK3 Antibodies)/2 MAP kinase (show MAPK1 Antibodies) signaling pathway.

  10. DARC antigen is associated with a likelihood for patients to develop leg ulcers in sickle cell disease.

Mouse (Murine) Duffy Blood Group, Chemokine Receptor (DARC) interaction partners

  1. Ackr1 deficiency appears to be protective in the ApoE (show APOE Antibodies) knockout model of atherogenesis, but it is associated with only modest changes in cytokine and chemokine (show CCL1 Antibodies) expression as well as T-cell subset frequency and inflammatory macrophage content.

  2. Darc plays a role in modulating the regulation of inflammatory response to bone injury and that lack of Darc expression promotes cartilage formation in fracture calluses but does not affect bony union or fracture healing at 21 days post-fracture.

  3. The data showed a role for erythrocyte DARC as a chemokine (show CCL1 Antibodies) reservoir and that endothelial DARC contributes to the pathogenesis of experimental autoimmune encephalomyelitis by shuttling chemokines across the blood-brain barrier.

  4. DARC is crucial for chemokine (show CCL1 Antibodies)-mediated leukocyte recruitment in vivo.

  5. Plasmodium yoelii uses the murine Duffy antigen receptor for chemokines as a receptor for normocyte invasion and an alternative receptor for reticulocyte invasion.

  6. Vascular endothelial cells may induce Duffy protein to regulate leukocytes and/or chemokine (show CCL1 Antibodies) trafficking

  7. role of the Duffy antigen and glycophorin A (show GYPA Antibodies) as receptors for rodent malaria parasite invasion of erythrocytes

  8. DARC functions to clear angiogenic CXC chemokines from the prostate tumor microcirculation

  9. Darc regulates bone mineral density (BMD (show BEST1 Antibodies))negatively by increasing osteoclast formation. Darc is proposed as a candidate gene for chromosome 1 BMD (show BEST1 Antibodies) QTL2.

  10. Loss of red cell chemokine (show CCL1 Antibodies) scavenging promotes transfusion-related lung inflammation

Cow (Bovine) Duffy Blood Group, Chemokine Receptor (DARC) interaction partners

  1. the 5' flanking region of the DARC gene was isolated and characterized

DARC Antigen Profile

Protein Summary

The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with DARC

  • Duffy blood group, chemokine receptor (DARC) antibody
  • Duffy blood group, atypical chemokine receptor (DARC) antibody
  • Duffy blood group, atypical chemokine receptor (Darc) antibody
  • Duffy blood group, chemokine receptor (Darc) antibody
  • AA162249 antibody
  • Ackr1 antibody
  • CCBP1 antibody
  • CD234 antibody
  • DARC antibody
  • Dfy antibody
  • ESTM35 antibody
  • FY antibody
  • GPD antibody
  • GpFy antibody
  • WBCQ1 antibody

Protein level used designations for DARC

Duffy blood group, chemokine receptor , duffy antigen/chemokine receptor , Duffy antigen/chemokine receptor , Duffy blood group antigen , Fy glycoprotein , atypical chemokine receptor 1 , glycoprotein D , plasmodium vivax receptor , Duffy antigen receptor for chemokines , blood group antigen , duffy antigen/receptor for chemokine glycoprotein

GENE ID SPECIES
396618 Sus scrofa
478969 Canis lupus familiaris
100398804 Callithrix jacchus
100458473 Pongo abelii
100500770 Papio anubis
2532 Homo sapiens
689105 Rattus norvegicus
13349 Mus musculus
528076 Bos taurus
745985 Pan troglodytes
719284 Macaca mulatta
Selected quality suppliers for anti-DARC (DARC) Antibodies
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