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The Fos gene family consists of 4 members FOSL1, and FOSL2. Additionally we are shipping FOSL2 Proteins (8) and FOSL2 Kits (5) and many more products for this protein.
Showing 10 out of 134 products:
Hamster Polyclonal FOSL2 Primary Antibody for EIA, IHC (p) - ABIN952358
Bolat, Keklikoglu: Immunoreactivity of ATF-2 and Fra-2 in human dental follicle. in Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society 2010
Show all 4 references for ABIN952358
Human Polyclonal FOSL2 Primary Antibody for EIA, WB - ABIN952359
Tanimoto, Arakawa, Sanada, Miyachi, Ishii: Changes in muscle activation and force generation patterns during cycling movements because of low-intensity squat training with slow movement and tonic force generation. in Journal of strength and conditioning research / National Strength & Conditioning Association 2009
Show all 4 references for ABIN952359
Human Polyclonal FOSL2 Primary Antibody for IP - ABIN515798
Wrann, Eguchi, Bozec, Xu, Mikkelsen, Gimble, Nave, Wagner, Ong, Rosen: FOSL2 promotes leptin gene expression in human and mouse adipocytes. in The Journal of clinical investigation 2012
Hamster Polyclonal FOSL2 Primary Antibody for IHC (p), WB - ABIN654925
Bozec, Bakiri, Jimenez, Schinke, Amling, Wagner: Fra-2/AP-1 controls bone formation by regulating osteoblast differentiation and collagen production. in The Journal of cell biology 2010
Chicken Polyclonal FOSL2 Primary Antibody for IHC, WB - ABIN2777246
Molven, Houge, Berger: Chromosomal assignment of the human gene encoding the Fos-related antigen-2 (FRA2) to chromosome 2p22-p23. in Genomics 1997
The binding and expression of c-Fos/Fra-2 increased as a function of severity of tongue lesions, yet selective participation of c-Jun appears to promote poor differentiation and aggressive tumorigenesis.
FOSL2 facilitates TGF-beta1 (show TGFB1 Antibodies)-induced migration by interaction with Smad3 (show SMAD3 Antibodies) in non-small cell lung cancer.FOSL2 positively regulates TGF-beta1 (show TGFB1 Antibodies) signalling .
FRA2 is a STAT5 (show STAT5A Antibodies) target gene regulated by IL-2 (show IL2 Antibodies) in human CD4 (show CD4 Antibodies) T cells.
we show that the suppression was mediated, at least in part, by a suspension culture-driven decrease in the levels of two members of the AP1 (show FOSB Antibodies) transcription factor complex, c-Jun (show JUN Antibodies) and Fra2
SOX4 is a direct target gene of FRA-2 and induces expression of HDAC8 (show HDAC8 Antibodies) in adult T-cell leukemia/lymphoma.
This study suggests that Fra-2 transgenic mice as an animal model of systemic sclerosis-associated pulmonary arterial hypertension display main characteristic features of the human disease.
results demonstrate the presence of a common oncogenic cascade initiated by FRA2/JUND (show JUND Antibodies) in CCR4 (show CCR4 Antibodies)-expressing mature T-cell malignancies such as ATLL and CTCLs
FOSL2 is a critical regulator of leptin (show LEP Antibodies) expression in adipocytes
Results suggest that Fra-2 protein may be more effective than ATF-2 (show ATF2 Antibodies) protein in cyst formation originated from epithelial cells of dental follicles.
These findings reveal a novel function of Fra-2/AP-1 (show FOSB Antibodies) as a positive regulator of bone and matrix formation in mice and humans.
Deletion of Fra-2 leads to increased PPARgamma2 (show PPARG Antibodies) expression and adipocyte differentiation as well as increased adipocyte apoptosis through upregulation of hypoxia-inducible factors.
Osteoblast-specific expression of Fra-2/AP-1 (show JUN Antibodies) controls adiponectin (show ADIPOQ Antibodies) and osteocalcin (show BGLAP Antibodies) expression and affects metabolism.
Cytokine-mediated Fra-2 expression and stabilization is linked to regulation of myogenic progenitor cells.
AP-1 (show JUN Antibodies) composed with JunD (show JUND Antibodies) and Fra2 protein plays a primary role in enhancing the transcription level of the CD11c (show ITGAX Antibodies) gene in dendritic cells
Identify Fra-2 as an O(2)-sensitive transcriptional regulator of inducible TGFbeta (show TGFB1 Antibodies) expression and position Fra-2 as an important player in reoxygenation-induced myocardial fibrosis.
These findings reveal a novel function of Fra-2/AP-1 (show JUN Antibodies) as a positive regulator of bone and matrix formation in mice and humans.
Since transgenic overexpression of Fra-2 causes not only fibrosis but also vascular disease, Fra-2 might be an interesting novel candidate for molecular-targeted therapies for systemic sclerosis.
AP-1 transrepressing retinoic acid does not deplete coactivators or AP-1 monomers but may target specific Jun or Fos containing dimers
Fra2 is a novel transcription factor important for skeletogenesis by affecting chondrocyte differentiation
Fos-like antigen 2 (Fosl2), potentiates the rate of myocardial accretion from the zebrafish second heart field.
The Fos gene family consists of 4 members FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
fos-related antigen 2
, FOS-like antigen 2
, phospholipase B1