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FOXL2 encodes a forkhead transcription factor. Additionally we are shipping FOXL2 Proteins (6) and many more products for this protein.
Showing 10 out of 97 products:
Human Polyclonal FOXL2 Primary Antibody for ChIP, ELISA - ABIN249959
Jamieson, Butzow, Andersson, Alexiadis, Unkila-Kallio, Heikinheimo, Fuller, Anttonen: The FOXL2 C134W mutation is characteristic of adult granulosa cell tumors of the ovary. in Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2010
Show all 22 references for ABIN249959
Human Polyclonal FOXL2 Primary Antibody for EIA, FACS - ABIN952375
Nakashima, Chung, Takahashi, Kamatani, Kawaguchi, Tsunoda, Hosono, Kubo, Nakamura, Zembutsu: A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population. in Nature genetics 2010
Show all 5 references for ABIN952375
Human Polyclonal FOXL2 Primary Antibody for IHC, ELISA - ABIN185040
Crisponi, Deiana, Loi, Chiappe, Uda, Amati, Bisceglia, Zelante, Nagaraja, Porcu, Ristaldi, Marzella, Rocchi, Nicolino, Lienhardt-Roussie, Nivelon, Verloes, Schlessinger, Gasparini, Bonneau, Cao, Pilia: The putative forkhead transcription factor FOXL2 is mutated in blepharophimosis/ptosis/epicanthus inversus syndrome. in Nature genetics 2001
Show all 3 references for ABIN185040
Human Polyclonal FOXL2 Primary Antibody for FACS, WB - ABIN654125
Kraoua, Chaabouni, Trabelsi, Chelly, Maazoul, Ben Abdallah, Boukthir, Barsaoui, Chaabouni, Mrad: FOXL2 mutations in Tunisian patients with blepharophimosis-ptosis-epicanthus inversus syndrome. in Clinical genetics 2010
Show all 2 references for ABIN654125
Cow (Bovine) Polyclonal FOXL2 Primary Antibody for WB - ABIN2777885
Tang, Wang, Lin, Sun, Wang, Yu: Mutation analysis of the FOXL2 gene in Chinese patients with blepharophimosis-ptosis-epicanthus inversus syndrome. in Mutagenesis 2006
Rat (Rattus) Polyclonal FOXL2 Primary Antibody for WB - ABIN610539
Ayllón, Cayla, García, Roncal, Fernández, Albar, Martínez, Rebollo: Bcl-2 targets protein phosphatase 1 alpha to Bad. in Journal of immunology (Baltimore, Md. : 1950) 2001
Data show that cytochrome P450 (show CYP Antibodies) enzymes Cyp17 (show CYP17A1 Antibodies)-I, Cyp11c1 (show CYP11B2 Antibodies), Cyp19a1a and Cyp19a1b and one of their regulators forkhead protein (show FOXO4 Antibodies) Foxl2a were detected both in the testis and ovary.
Data indicate taht monocrotophos (MCP) exposure modulated gene expression of forkhead transcription factor gene L2 (foxl2), doublesex/mab-3 related transcription factor 1 (dmrt1), gonadal aromatase (cyp19a1a) and brain aromatase (cyp19a1b).
Effects of sexual steroids on the expression of foxl2 in Gobiocypris rarus
Xenopus W-linked DM-W induces foxl2 expression during ovary formation.
Data indicate that a balance between supporting cell (show PTPRJ Antibodies) self-renewal and differentiation is maintained in the developing ovary by relative Wnt4 (show WNT4 Antibodies) protein/beta-catenin (show CTNNB1 Antibodies) and p27Kip1 (show CDKN1B Antibodies) protein (p27 (show CDKN1B Antibodies))/Forkhead box L2 (FOXL2) activities.
Data indicate that the hypothalamic-pituitary-gonadal axis controls expression of Foxl2 in pituitary gonadotropes primarily through positive feedback from ovarian hormones.
FOXL2 mobilizes estrogen signaling to establish a coherent feed-forward loop repressing Sox9 (show SOX9 Antibodies).
Foxl2 has a crucial role in postnatal uterine maturation and could help to understand sub-fertility predisposition in women.
Results support FOXL2 as a master transcription factor in a spectrum of developmental processes, including growth, cartilage and bone formation. Its action overlaps that of SOX9 (show SOX9 Antibodies), though they are antagonistic in female vs male gonadal sex determination but conjoint in cartilage and skeletal development.
Microarray expression profiling of whole adrenal mRNA from ovariectomized vs. intact mice demonstrated selective upregulation of gonadal-like genes including Spinlw1 and Insl3 (show INSL3 Antibodies) in GDX (show UBL4A Antibodies)-induced adrenocortical tumors of the mouse.
our results demonstrate the necessity of FOXL2 for proper FSH (show BRD2 Antibodies) production in mice and implicate FOXL2 in integration of transcription factors at the level of the FSHbeta promoter.
Results show that a piggyBac insertion ~160 kb upstream of the transcription start site of Foxl2 partially disrupted its expression resulting in BPES (Blepharophimosis, ptosis, epicanthus inversus syndrome)-like conditions.
AMH (show AMH Antibodies) is an endogenous target gene of FOXL2. AMH (show AMH Antibodies) and FOXL2 collaboratively work to reserve ovarian follicles.
In this review, we focus on the role of four specific FOX factors (FOXD1 (show FOXD1 Antibodies), FOXL2, FOXO1 (show FOXO1 Antibodies) and FOXP3 (show FOXP3 Antibodies)) in gonadotropin hormone production
genetic association study in two families with blepharophimosis-ptosis-epicanthus inversus syndrome type 1: Two distinct mutations, a missense p.H104R change and an in-frame p.A222_A231dup10 duplication in FOXL2 gene are identified in three women.
suggests the potential of pS33 FOXL2 to serve as a new biomarker for the diagnosis of adult-type GCT (show QPCT Antibodies)
Our combined analysis identifies potential candidate genes, whose alterations might contribute to adult-type Ovarian granulosa cell tumors formation/progression together with the recurrent FOXL2 somatic mutation.
Describe microcystic stromal tumor as a distinctive ovarian sex cord-stromal neoplasm characterized by FOXL2, SF-1 (show NR5A1 Antibodies), WT-1 (show WT1 Antibodies), Cyclin D1 (show CCND1 Antibodies), and beta-catenin (show CTNNB1 Antibodies) nuclear expression and CTNNB1 (show CTNNB1 Antibodies) mutations.
Foxl2 deletion in either Cranial Neural Crest Cells (CNCCs) or Cranial Mesodermal Cells (CMCs (show GPSM2 Antibodies)) prevents eyelid closure and induces subtle skeletal developmental defects.
C134W mutation affects granulosa cell tumor development via differential posttranslational modifications of FOXL2 by GSK3B (show GSK3b Antibodies).
Two novel FOXL2 mutations (c.675_690delinsT, and p.Leu75Phe) were identified in Chinese families with blepharophimosis-ptosis-epicanthus inversus syndrome.
Uterine tumors resembling ovarian sex cord tumors do not harbor FOXL2 mutation
FOXL2 p.C134W mutation-positive adult-type granulosa cell tumor of the ovary may not be common in the Japanese.
report the 402C-->G FOXL2 mutation status in five epithelial ovarian lesions in women aged 45-77 years showing stromal proliferations that were morphologically indistinguishable from adult granulosa cell tumour
results therefore identify FOXL2 as a bona fide female sex-determining gene in the goat
This gene encodes a forkhead transcription factor. The protein contains a fork-head DNA-binding domain and may play a role in ovarian development and function. Mutations in this gene are a cause of blepharophimosis syndrome and premature ovarian failure 3.
forkhead box L2
, forkhead box protein L2
, transcription factor FOXL2
, forkhead transcription factor L2
, foxl2 protein
, fork-head box L2 transcription factor
, pituitary forkhead factor
, putative transcription factor foxl2
, forkhead transcription factor FOXL2
, Forkhead box protein L2