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The protein encoded by FOXP3 is a member of the forkhead/winged-helix family of transcriptional regulators. Additionally we are shipping FOXP3 Kits (38) and FOXP3 Proteins (16) and many more products for this protein.
Showing 10 out of 513 products:
Dog (Canine) Polyclonal FOXP3 Primary Antibody for ChIP, EIA - ABIN782895
Banham, Brown, Lyne, Schulze, Hallermann: Is FOXP3 expressed in cutaneous T-cell lymphomas? in European journal of haematology 2008
Show all 13 references for ABIN782895
Dog (Canine) Polyclonal FOXP3 Primary Antibody for EIA, WB - ABIN374156
Stahl, Fauti, Ullrich, Bopp, Kubach, Rust, Labhart, Alexiadis, Becker, Hafner, Weith, Lenter, Jonuleit, Schmitt, Mennerich: miR-155 inhibition sensitizes CD4+ Th cells for TREG mediated suppression. in PLoS ONE 2009
Show all 13 references for ABIN374156
Human Polyclonal FOXP3 Primary Antibody for EIA, IHC (p) - ABIN357961
Eisenberger, Seifried, Patey, Kappeler, Noel, Frey, Körner: FoxP3 positive T cells in graft biopsies from living donor kidney transplants after donor-specific transfusions. in Transplantation 2009
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Human Polyclonal FOXP3 Primary Antibody for FACS, IHC (p) - ABIN389295
Ouaked, Mantel, Bassin, Burgler, Siegmund, Akdis, Schmidt-Weber: Regulation of the foxp3 gene by the Th1 cytokines: the role of IL-27-induced STAT1. in Journal of immunology (Baltimore, Md. : 1950) 2009
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Cow (Bovine) Polyclonal FOXP3 Primary Antibody for IHC, WB - ABIN2777561
Takahata, Nomura, Takada, Ohga, Furuno, Hikino, Nakayama, Sakaguchi, Hara: CD25+CD4+ T cells in human cord blood: an immunoregulatory subset with naive phenotype and specific expression of forkhead box p3 (Foxp3) gene. in Experimental hematology 2004
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Human Polyclonal FOXP3 Primary Antibody for IHC, ELISA - ABIN184677
Miyara, Amoura, Parizot, Badoual, Dorgham, Trad, Kambouchner, Valeyre, Chapelon-Abric, Debré, Piette, Gorochov: The immune paradox of sarcoidosis and regulatory T cells. in The Journal of experimental medicine 2006
Show all 2 references for ABIN184677
Human Polyclonal FOXP3 Primary Antibody for DB - ABIN650867
Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: New genetic associations detected in a host response study to hepatitis B vaccine. in Genes and immunity 2010
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Mouse (Murine) Monoclonal FOXP3 Primary Antibody for WB - ABIN1449247
Ono, Yaguchi, Ohkura, Kitabayashi, Nagamura, Nomura, Miyachi, Tsukada, Sakaguchi: Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1. in Nature 2007
Human Monoclonal FOXP3 Primary Antibody for IHC (p) - ABIN1688658
Mariya, Hirohashi, Torigoe, Asano, Kuroda, Yasuda, Mizuuchi, Sonoda, Saito, Sato: Prognostic impact of human leukocyte antigen class I expression and association of platinum resistance with immunologic profiles in epithelial ovarian cancer. in Cancer immunology research 2014
analysis of Foxp3-based immunoregulation and autoimmunity in zebrafish
correlation between the expression of t-bet, stat6 (show STAT6 Antibodies) and foxp3 with other genes involved in Th and T(reg (show KCNH2 Antibodies)) responses
cloning and characterization of the full-length cDNA of Atlantic salmon Foxp3, which possesses a Forkhead domain, a zinc finger domain and a leucine-zipper domain as its counterpart in mammals
FOXP3 was expressed in lung adenocarcinoma tissue and A549 cells. FOXP3 inhibition decreased cell proliferation, migration, and invasion as well as the secretion of inhibitory cytokines. It enhanced lung adenocarcinoma cell proliferation via upregulating the levels of the cell cycle G1/S checkpoint gene CCND1 (show CCND1 Antibodies).
it was observed that ER stimulated gene expression by interacting with MEIS1 (show MEIS1 Antibodies) and FOXP3, and ER inhibited gene expression by interacting with THRB (show THRB Antibodies) and GRHL1 (show GRHL1 Antibodies).
this study shows that there is no significant difference in mucosal FOXP3 expression in Ulcerative Colitis patients with moderate-to-severe disease activity compared to those in remission
FOXP3 single nucleotide polymorphism rs2232365 is associated with autism in Iranian autistic patients.
In this work, we analyzed the expression of CD133, FOXP3, ABCG2 (show ABCG2 Antibodies) and CD24 (show CD24 Antibodies) in women affected by vulvar cancer, correlating these with common clinical prognostic factors
Under conditions of directed induction of phenotypic changes in CD4 (show CD4 Antibodies)(+) lymphocytes to regulatory T cells (Treg), pregnancy-specific at high concentrations (10 and 100 mug/mL) increased FOXP3 expression. The evaluation of the spontaneous expression level of FOXP3 mRNA showed that pregnancy-specific beta1-glycoprotein (1 and 100 mug/mL) stimulated the expression of this factor in mononuclear cells and isolated CD4 (show CD4 Antibodies)(+) lym...
MiR-16 (show GDE1 Antibodies) may be involved in Th17/Treg imbalance in rheumatoid arthritis patients by affecting the expression of RORgt and FoxP3.
High CXCR4 (show CXCR4 Antibodies) expression in primary breast tumors (PTs (show PTS Antibodies)) was found to be associated with luminal A type tumor, suggesting more favorable outcome. In contrast, CCR7 (show CCR7 Antibodies) and FOXP3 expressions in PTs (show PTS Antibodies) represented luminal B tumors, pointing to more aggressive tumor behavior. Maspin (show SERPINB5 Antibodies) expression did not differ between luminal types.
Latest reports indicate that the FOXP3 gene mutation can contribute to carcinogenesis, which can be associated with immune response abnormalities. Infiltration of the Treg cells into tumor cells can be associated with prognosis. Understanding the biology of the FOXP3 gene may be crucial in developing new immunotherapeutics
Our results suggest that FOXP3 acts as a master switch governing the development and function of T-regulatory cells, whose functions include the inhibition of immune responses and temper inflammation
indirubin administration effectively suppressed CD4 (show CD4 Antibodies)(+) T cell infiltration in the colon of DSS (show PMP22 Antibodies)-induced UC mice and promoted the generation of Foxp3-expressing regulatory T cells
The data suggest that RORgt expression in Tregs contributes to an optimal suppressive capacity during gut (show GUSB Antibodies)-specific immune responses, rendering Foxp3-RORgt T cells as an important effector Treg subset in the intestinal system.
The ex vivo expression of transforming growth factor (TGF)-beta (show TGFB1 Antibodies) and factor Foxp3 were significantly higher in splenocytes of the experimental mice than the basal expression observed in the control cells.
These observations reveal an unexpected differential role of DJ-1 (show PARK7 Antibodies) in the development of nTregs and iTregs.
An IL-27 (show IL27 Antibodies)/Lag3 (show LAG3 Antibodies) axis enhances Foxp3+ regulatory T cell-suppressive function and therapeutic efficacy.
the presence of IL-2 (show IL2 Antibodies) during the in vitro generation of iTreg cells confers resistance to Th17 conversion but that IL-2 (show IL2 Antibodies) and retinoic acid (RA) cooperate to maintain Foxp3 expression following stimulation under Th17-polarizing conditions
Foxp3 has a rapid turn over in Treg partly controlled at the transcriptional level by the JAK (show JAK3 Antibodies)/STAT (show STAT1 Antibodies) pathway
NZW Tregs were less sensitive to limiting doses of trophic cytokines, IL-2 (show IL2 Antibodies) and -33, for population homeostasis and for maintenance of FoxP3 expression
Data show that tubacin can upregulate forkhead box P3 protein (show SLC10A3 Antibodies) (Foxp3) expression of CD4 (show CD4 Antibodies)(+) CD25 (show IL2RA Antibodies)(+) Tregs and enhances their cellular immunosuppressive capability.
YY1 (show YY1 Antibodies) interrupts Foxp3-dependent target gene expression by physically interacting with Foxp3 and by directly binding to the Foxp3 target genes.
sequenced the entire Foxp3 cDNA which is 1296 nucleotides in length and codes for a polypeptide of 432 amino acids
In a miniature swine lung transplantation model, the FOXP3 mRNA level in the peripheral blood was upregulated at an early phase of rejection
Experimental infection with bovine viral diarrhea virus did not provide evidence ofTreg activation based on expression of FoxP3 and CTLA4 (show CTLA4 Antibodies).
The expression of Foxp3 in CD4 (show CD4 Antibodies)(+) T cells from persistent lymphocytotic cattle was significantly increased.
There is a positive correlation between the intensity of CD25 (show IL2RA Antibodies) expression and the expression of the transcription Foxp3 factor in bovine CD8 (show CD8A Antibodies)(+) cells.
identification of Foxp3 expression in Treg cells
These findings revealed that despite the existence of a distinct bovine CD4 (show CD4 Antibodies)(+)CD25 (show IL2RA Antibodies)(high) T cell population, which showed Foxp3 transcription/expression, natural regulatory activity did not reside in this cell population
The correlation of TH17-related TLR4 (show TLR4 Antibodies) expression and Foxp3-positive cells in the rectal tissue of horses with inflammatory bowel disease is reported.
Expression levels of FOXP3 mRNA copy numbers were significantly increased in lesional compared to tumour-distant samples. There was no difference in FOXP3 expression in tumour-distant samples from equine sarcoid- compared with control horses.
results confirm FoxP3 expression in the horse, in contrast to the mouse, is regulated similarly to FOXP3 expression in humans and provide evidence that FoxP3 expression by conventional T cells may help regulate the developing immune response
The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
forkhead box protein P3
, regulatory protein Foxp3
, forkhead box P3
, forkhead box protein P3-like
, transcription factor foxp3
, immune dysregulation, polyendocrinopathy, enteropathy, X-linked
, immunodeficiency, polyendocrinopathy, enteropathy, X-linked
, forkhead/winged helix transcription factor 3