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anti-G Protein-Coupled Receptor 143 (GPR143) Antibodies

GPR143 encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. Additionally we are shipping G Protein-Coupled Receptor 143 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GPR143 4935 P51810
GPR143 18241 P70259
GPR143 302619  
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Top anti-G Protein-Coupled Receptor 143 Antibodies at antibodies-online.com

Showing 10 out of 42 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, ELISA Immunofluorescence analysis of LOVO cells, using GPR143 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF, ELISA 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated IHC (p) Anti-GPR143 antibody  ABIN1048724 IHC staining of human eye, retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of GPR143 expression in A549 (A), NS-1 (B), PC12 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$390.50
Details
Human Rabbit Un-conjugated IF, ELISA 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated ELISA, WB TheGPR143 Antibody is used in Western blot to detect GPR142 in HeLa cells lysates. 0.1 mg Log in to see 2 to 6 Days
$403.70
Details
Human Mouse Un-conjugated FACS, WB Western Blot analysis of GPR143 expression in transfected 293T cell line by GPR143 MaxPab polyclonal antibody.Lane 1: GPR143 transfected lysate(46.64 KDa).Lane 2: Non-transfected lysate. FACS analysis of negative control 293 cells (Black) and GPR143 expressing 293 cells (Green) using GPR143 purified MaxPab mouse polyclonal antibody. 50 μL Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB   500 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 11 to 13 Days
$541.80
Details

GPR143 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-G Protein-Coupled Receptor 143 Antibodies

  1. Human Polyclonal GPR143 Primary Antibody for IF, ELISA - ABIN1535711 : Ross, Grafham, Coffey, Scherer, McLay, Muzny, Platzer, Howell, Burrows, Bird, Frankish, Lovell, Howe, Ashurst, Fulton, Sudbrak, Wen, Jones, Hurles, Andrews, Scott, Searle, Ramser, Whittaker, Deadman et al.: The DNA sequence of the human X chromosome. ... in Nature 2005 (PubMed)

More Antibodies against G Protein-Coupled Receptor 143 Interaction Partners

Human G Protein-Coupled Receptor 143 (GPR143) interaction partners

  1. Downstream signaling from GPR143 controls RPE (show RPE Antibodies) secretion of pigment epithelium-derived factor (PEDF (show SERPINF1 Antibodies)), a potent neurotrophic and antiangiogenic factor.

  2. Five mutations in GPR143 gene were detected in each of the five families, including a novel nonsense mutation of c.333G>A,two novel splicing mutations of c.360+1G>C and c.659-1G>A, a novel small deletion mutation of c.43_50dupGACGCAGC.

  3. intronic mutation that creates a cryptic splice-donor site in GPR143 of patients with ocular albinism

  4. The GPR143 gene analysis identified an identical point mutation in two Ocular albinism 1 patients and their mothers .

  5. Melanosome-autonomous regulation of size and number: the OA1 receptor sustains PMEL (show PMEL Antibodies) expression.

  6. OA1 is involved in melanoma cell migration and that OA1induced melanoma cell migration is mediated through the RAS/RAF (show RAF1 Antibodies)/MEK (show MAP2K1 Antibodies)/ERK (show EPHB2 Antibodies) signaling pathway.

  7. a novel splicing site mutation of the GPR143 gene was found in a Han Chinese congenital ocular albinism pedigree.

  8. Data report that p.Y269X mutation of GPR143 gene is responsible for the pathogenesis of familial ocular albinism.

  9. These results identify the Oa1 transducer Galphai3 (show GNAI3 Antibodies) as the first downstream component in the Oa1 signaling pathway.

  10. The ocular albinism type 1 (OA1) GPCR is ubiquitinated and its traffic requires endosomal sorting complex responsible for transport (ESCRT) function.

Mouse (Murine) G Protein-Coupled Receptor 143 (GPR143) interaction partners

  1. OA1 expression in both neuronal and non-neuronal tissues was examined by immunohistochemical analyses, results suggested that OA1 may modulate the monoaminergic functions in both peripheral and central nervous systems

  2. Melanosome-autonomous regulation of size and number: the OA1 receptor sustains PMEL (show PMEL Antibodies) expression.

  3. These results identify the Oa1 transducer Galphai3 (show GNAI3 Antibodies) as the first downstream component in the Oa1 signaling pathway.

  4. OA1 interacts with MART-1 (show RTL1 Antibodies) at early stages of melanogenesis to control melanosome identity and composition.

  5. Asparagine at amino acid 106 is essential for N-glycosylation of the Oa1 protein. Mutation at amino acid 106 that eliminated glycosylation did not affect the endo/lysosomal distribution of Oa1 protein in cells.

  6. the ocular albinism type 1 gene expression is controlled by microphthalmia transcription factor (Mitf (show MITF Antibodies))

  7. The findings indicate that Oa1 is involved in the regulation of melanosome maturation at two steps, Oa1 controls the abundance of melanosomes in RPE (show RPE Antibodies) cells and has a function in the maintenance of a correct melanosomal size.

  8. G alpha i3, like Oa1, plays important role in melanosome biogenesis. Common Oa1-G alpha i3 signaling pathway may ultimately affect axonal growth through optic chiasm.

  9. data point to defective regulation of organelle transport in pigment cells in absence of OA1; results enlighten novel function for OA1 in pigment cells & suggest ocular albinism type 1 may result from a different mechanism than previously thought

G Protein-Coupled Receptor 143 (GPR143) Antigen Profile

Protein Summary

This gene encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in this gene cause ocular albinism type 1, also referred to as Nettleship-Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y.

Gene names and symbols associated with GPR143

  • G protein-coupled receptor 143 (GPR143) antibody
  • G protein-coupled receptor 143 (Gpr143) antibody
  • NYS6 antibody
  • Oa1 antibody
  • RGD1565799 antibody

Protein level used designations for GPR143

G-protein coupled receptor 143 , ocular albinism type 1 protein , MOA1 , homolog of human ocular albinism 1 (Nettleship-Falls) , ocular albinism type 1 protein homolog

GENE ID SPECIES
4935 Homo sapiens
18241 Mus musculus
302619 Rattus norvegicus
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