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Glucagon Proteins (GCG)

Transcriptional repressor that plays a central role in somatic cells of the gonad and is required for germ cell development. Additionally we are shipping Glucagon Antibodies (376) and Glucagon Kits (97) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse GCG GCG 77683 Q5DW34
GCG 79813 Q9H9B1
GCG 24952  
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Top Glucagon Proteins at

Showing 10 out of 33 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human GST tag Glucagon (GCG) (AA 53-89) protein (GST tag) 50 μg Log in to see 9 to 11 Days
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
HOST_Mammalian Cells Human His tag   50 μg Log in to see 5 Days
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
Yeast Guinea Pig His tag   1 mg Log in to see 56 to 66 Days

GCG Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Rat (Rattus) ,

Top referenced Glucagon Proteins

  1. Human GCG Protein expressed in Escherichia coli (E. coli) - ABIN667503 : Rouillé, Martin, Steiner: Differential processing of proglucagon by the subtilisin-like prohormone convertases PC2 and PC3 to generate either glucagon or glucagon-like peptide. in The Journal of biological chemistry 1995 (PubMed)
    Show all 2 references for ABIN667503

  2. Human GCG Protein expressed in Escherichia coli (E. coli) - ABIN1047068 : White, Saunders: Structure of the human glucagon gene. in Nucleic acids research 1986 (PubMed)

More Proteins for Glucagon (GCG) Interaction Partners

Rhesus Monkey Glucagon (GCG) interaction partners

  1. The findings indicate that the brainstem preproglucagon neuronal system is highly conserved between rat and non-human primate

Mouse (Murine) Glucagon (GCG) interaction partners

  1. AMPK (show PRKAA1 Proteins) antagonizes hepatic glucagon signalling via phosphorylation-induced PDE4B (show PDE4B Proteins) activation

  2. The stress-induced Brg1 (show SMARCA4 Proteins)-G9a (show EHMT2 Proteins)/GLP-Dnmt3 interactions and sequence of repressive chromatin assembly on Myh6 (show MYH6 Proteins) promoter illustrates a molecular mechanism by which the heart epigenetically responds to environmental signals.

  3. Data suggest that pharmacological stimulation of serotonin 5Ht1b (show HTR1B Proteins) receptor enhances up-regulation of plasma Glp1 (glucagon-like peptide 1) induced by Dpp4 (dipeptidylpeptidase 4 (show DPP4 Proteins)) inhibition independently of feeding and also improves glucose tolerance.

  4. Deletion of AMPK alpha 1 (show PRKAA1 Proteins) and alpha 2 in proglucagon-expressing cells results in increased L-cell mass and elevated circulating GLP-1 levels.

  5. The results suggest that TGR5 (show GPBAR1 Proteins) activation mediates cross-talk between alpha- and beta-cells by switching from glucagon to GLP-1 to restore beta- cell mass and function under hyperglycemic conditions.

  6. The present study reveals the activation of autophagy to mediate the anti-diabetic effect of GLP-1.

  7. the acute combined administration of the strongly insulinotropic GLP-1 and glucagon, both in vivo and in vitro, did not induce any additive or synergistic action on glucose-stimulated insulin (show INS Proteins) secretion.

  8. Data (including data from studies in transgenic mice) suggest neurotensin/Nts (show NTS Proteins), GLP-1, and peptide YY are closely co-expressed and co-secreted within enteroendocrine cells in ileum mucosa; however, Nts (show NTS Proteins) is stored in distinct/separate secretory granules.

  9. CEACAM2 (show CEACAM2 Proteins) regulates insulin (show INS Proteins) secretion, at least in part, by a GLP-1-mediated mechanism, independent of confounding metabolic factors.

  10. These data suggest that GLP-1 released from NTS (show NTS Proteins) neurons can reduce highly palatable food intake by suppressing mesolimbic DA signaling.

Human Glucagon (GCG) interaction partners

  1. GLP-1 secretion increased in response to inflammatory stimuli in humans, which was associated to parameters of glucose metabolism and best predicted by IL6 (show IL6 Proteins).

  2. Among young and healthy adults, GLP-1 levels are strongly and independently related to body fat mass especially in men, but not body mass index or waist circumference.

  3. Glucagon circulates in patients without a pancreas and glucose stimulation of the gastrointestinal tract elicits significant hyperglucagonemia in these patients.

  4. There is minor contribution of endogenous GLP-1 and GLP-2 to postprandial lipemia in obese men.

  5. Data suggest that endocrine responses differ between jejunal and gastric enteral feeding, with higher peak plasma CCK (cholecystokinin), PYY (peptide YY), and GLP-1/2 (glucagon-like peptides 1/2) concentrations being attained after jejunal feeding.

  6. Data suggest that capsaicin, an appetite suppressant dietary supplement (here, administered via intraduodenal infusion), does not act via alteration of secretion of satiety hormones GLP-1 (GLP-1) and PYY (peptide YY).

  7. Data show that NCI-H716 cells were immunostained for tumor necrosis factor (show TNF Proteins) receptor TNFR1 (show TNFRSF1A Proteins), and TNFalpha (show TNF Proteins) treatment enhances glucagon-like peptide-1 (GLP-1) secretion.

  8. active GLP-1 produced in the islet stimulates cholecystokinin (show CCK Proteins) production and secretion in a paracrine manner via cyclic AMP (show APRT Proteins) and CREB (show CREB1 Proteins).

  9. Data suggest that secretion of insulin (show INS Proteins) and glucagon is up-regulated in subjects with type 2 diabetes with dyssomnia as compared to subjects with type 2 diabetes without dyssomnia; those with dyssomnia exhibit prehypertension and insulin (show INS Proteins) resistance.

  10. Data suggest plasma GLP1 (glucagon-like peptide 1) and PYY (peptide YY) can be regulated by digestion-resistant diet factors; intake of soluble dietary fiber (prebiotic Fibersol-2) in a tea with meal up-regulated plasma GLP1/PYY and decreased hunger.

Cow (Bovine) Glucagon (GCG) interaction partners

  1. data demonstrate that cattle express proglucagon and glucagon-like peptide 2 receptor (show GLP2R Proteins) mRNA primarily in small intestinal and colon tissues and increased nutrient intake increases ileal proglucagon mRNA and plasma glucagon-like peptide 2

Pig (Porcine) Glucagon (GCG) interaction partners

  1. The patterns of colocalization of the K cell marker, glucagon-like insulinotropic peptide, and L cell markers, glucagon like peptide-1 and peptide YY, in enteroendocrine cells of the small intestine and colon of mouse and pig, were investigated.

Glucagon (GCG) Protein Profile

Protein Summary

Transcriptional repressor that plays a central role in somatic cells of the gonad and is required for germ cell development. Able to repress GATA transcription factor function (By similarity).

Gene names and symbols associated with Glucagon Proteins (GCG)

  • glucagon (GCG)
  • euchromatic histone methyltransferase 1 (Ehmt1)
  • euchromatic histone-lysine N-methyltransferase 1 (EHMT1)
  • glucagon (Gcg)
  • glucagon (LOC100341777)
  • glucagon (gcg)
  • glucagon-like peptide 2 receptor (Glp2r)
  • mast cell protease 10 (Mcpt10)
  • zinc finger, GATA-like protein 1 (ZGLP1)
  • 9230102N17Rik protein
  • 9530092J08Rik protein
  • bA188C12.1 protein
  • D330003E03 protein
  • Eu-HMTase1 protein
  • EUHMTASE1 protein
  • FP13812 protein
  • GATAD3 protein
  • GCG protein
  • gcg-A protein
  • gcg1 protein
  • GLP protein
  • GLP-1 protein
  • GLP-2 protein
  • GLP1 protein
  • GLP2 protein
  • Glu protein
  • GRPP protein
  • KMT1D protein
  • mKIAA1876 protein
  • PPG protein

Protein level used designations for Glucagon Proteins (GCG)

glucagon , preproglucagon B , G9a-like protein 1 , euchromatic histone-lysine N-methyltransferase 1 , histone-lysine N-methyltransferase EHMT1 , lysine N-methyltransferase 1D , G9a like protein , H3-K9-HMTase 5 , histone H3-K9 methyltransferase 5 , histone-lysine N-methyltransferase, H3 lysine-9 specific 5 , glicentin-related polypeptide , glucagon-like peptide 1 , glucagon-like peptide 2 , preproglucagon , proglucagon , glucagon-like peptide I , glucagon-like peptide-1 , glucagon I , glucagon-1 , proglucagon I , glucagon preproprotein , preproglucagon A , G protein-coupled receptor GLP2R , GLP-2 receptor , GLP-2-R , GLP-2R , GLP II , GLP-2 , granzyme-like protein 2 , granzyme-like protein II , mast cell protease X , rMCP-10 , rMCP-X , GATA like protein 1 , GATA like protein-1 , GATA zinc finger domain containing 3 , GATA-like protein 1 , GATA-type zinc finger protein 1

705508 Macaca mulatta
100545791 Meleagris gallopavo
77683 Mus musculus
79813 Homo sapiens
2641 Homo sapiens
280802 Bos taurus
397595 Sus scrofa
14526 Mus musculus
24952 Rattus norvegicus
403571 Canis lupus familiaris
443179 Ovis aries
100341777 Oryctolagus cuniculus
100135526 Cavia porcellus
373686 Xenopus laevis
396196 Gallus gallus
93896 Mus musculus
54269 Rattus norvegicus
100125288 Homo sapiens
101097825 Felis catus
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