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anti-Heat Shock 22kDa Protein 8 (HSPB8) Antibodies

The protein encoded by HSPB8 belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. Additionally we are shipping Heat Shock 22kDa Protein 8 Proteins (21) and Heat Shock 22kDa Protein 8 Kits (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HSPB8 26353 Q9UJY1
HSPB8 80888 Q9JK92
HSPB8 113906 Q9EPX0
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Top anti-Heat Shock 22kDa Protein 8 Antibodies at antibodies-online.com

Showing 10 out of 141 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-HSPB8 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated EIA, WB 20 μg Log in to see 6 to 8 Days
$203.50
Details
Human Goat Un-conjugated ELISA, WB ABIN184852 staining (1µg/ml) of human muscle lysate (RIPA buffer, 30µg... 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Mouse Un-conjugated ICC, IF, IHC, ELISA, WB HSP22 (3C12 H11), Mouse backskin. Rat tissue Mix WB 1 in 1000 Hsp22 monomer and dimer. 100 μg Log in to see 3 to 4 Days
$383.90
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-HSPB8 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:... WB Suggested Anti-HSPB8  Antibody Titration: 0.2-1 µg/mL ELISA Titer: ... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse HRP ICC, IF, IHC, ELISA, WB   100 μg Log in to see 3 to 4 Days
$422.40
Details
Human Mouse FITC ICC, IF, IHC, ELISA, WB   100 μg Log in to see 3 to 4 Days
$426.80
Details
Human Mouse Alkaline Phosphatase (AP) ICC, IF, IHC, ELISA, WB   100 μg Log in to see 3 to 4 Days
$429.00
Details
Human Mouse Biotin ICC, IF, IHC, ELISA, WB   100 μg Log in to see 3 to 4 Days
$431.20
Details
Human Mouse PE ICC, IF, IHC, ELISA, WB   100 μg Log in to see 3 to 4 Days
$432.30
Details

HSPB8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Top referenced anti-Heat Shock 22kDa Protein 8 Antibodies

  1. Human Monoclonal HSPB8 Primary Antibody for ICC, IF - ABIN863103 : Sun, Fontaine, Rest, Shelden, Welsh, Benndorf: Interaction of human HSP22 (HSPB8) with other small heat shock proteins. in The Journal of biological chemistry 2004 (PubMed)
    Show all 5 references for ABIN863103

  2. Human Monoclonal HSPB8 Primary Antibody for ICC, IF - ABIN2484241 : Kappé, Verschuure, Philipsen, Staalduinen, Van de Boogaart, Boelens, De Jong: Characterization of two novel human small heat shock proteins: protein kinase-related HspB8 and testis-specific HspB9. in Biochimica et biophysica acta 2001 (PubMed)
    Show all 4 references for ABIN2484241

  3. Human Monoclonal HSPB8 Primary Antibody for ICC, IF - ABIN2484238 : Benndorf, Sun, Gilmont, Biederman, Molloy, Goodmurphy, Cheng, Andrews, Welsh: HSP22, a new member of the small heat shock protein superfamily, interacts with mimic of phosphorylated HSP27 ((3D)HSP27). in The Journal of biological chemistry 2001 (PubMed)
    Show all 4 references for ABIN2484238

  4. Human Monoclonal HSPB8 Primary Antibody for ICC, IF - ABIN2484234 : Kim, Seit-Nebi, Gusev: The problem of protein kinase activity of small heat shock protein Hsp22 (H11 or HspB8). in Biochemical and biophysical research communications 2004 (PubMed)
    Show all 4 references for ABIN2484234

  5. Cow (Bovine) Polyclonal HSPB8 Primary Antibody for WB - ABIN2786018 : Carra, Seguin, Landry: HspB8 and Bag3: a new chaperone complex targeting misfolded proteins to macroautophagy. in Autophagy 2008 (PubMed)

More Antibodies against Heat Shock 22kDa Protein 8 Interaction Partners

Human Heat Shock 22kDa Protein 8 (HSPB8) interaction partners

  1. expands the understanding of disease mechanisms, tissue involvement, and phenotypic outcome of HSPB8 mutations

  2. our findings suggest the existence of a so-far unrecognized quality control mechanism involving BAG3 (show BAG3 Antibodies), HSPB8 and p62/SQSTM1 (show SQSTM1 Antibodies) for accurate remodelling of actin-based mitotic structures that guide spindle orientation.

  3. This study demonstreated that expression of HSPB8 was restricted to GFAP (show GFAP Antibodies)+ astrocytes in patient with multiple sclerosis.

  4. Pangenomic profiling of velcade-sensitive and resistant cells showed that the small heat shock protein HSPB8 was overexpressed in multiple myeloma resistant cells.

  5. HSP22 acts as a positive regulator in TGF-alpha (show TGFA Antibodies)-induced migration of ovarian cancer cells, subsequently directing ovarian cancer toward progression.

  6. HSP22 plays an important role on gastric tumor aggressiveness and prognosis and may act as a promising target for prognostic prediction.

  7. Mutant HSPB8 causes protein aggregates and a reduced mitochondrial membrane potential in dermal fibroblasts from distal hereditary motor neuropathy patients.

  8. The expression of HspB8 inhibits the growth of genetically diverse melanoma cells that include caspase-1 (show CASP1 Antibodies) activation outside of the realm of the inflammasome, mTORC1-dependent Beclin-1 (show BECN1 Antibodies) upregulation and its cleavage by the activated caspase-1 (show CASP1 Antibodies).

  9. findings show that during heat shock recovery NF-kappaB (show NFKB1 Antibodies) activates selective removal of misfolded or aggregated proteins by controlling expression of BAG3 (show BAG3 Antibodies) and HSPB8 and by modulating the level of the BAG3 (show BAG3 Antibodies)-HspB8 complex

  10. we observed upregulation of HSPB8 and BAG3 (show BAG3 Antibodies) selectively in astrocytes located within the degenerated areas of patients with protein aggregation diseases

Mouse (Murine) Heat Shock 22kDa Protein 8 (HSPB8) interaction partners

  1. Increased Hsp20 (show HSPB6 Antibodies) expression protects against OGDR-induced Golgi fragmentation and apoptosis, likely through interaction with Bax (show BAX Antibodies) and subsequent amelioration of the OGDR-induced elevation in p115 (show ARHGAP4 Antibodies) cleavage via the Fas (show FAS Antibodies)/FasL (show FASL Antibodies) signaling pathway.

  2. Translocation of both Hsp22 and iNOS to the mitochondria is necessary for Hsp22-mediated stimulation of oxidative phosphorylation

  3. analysis of the phenotype of cardiomyopathy in cardiac-specific heat shock protein B8 K141N transgenic mouse

  4. The results of this study strongly suggested that Hspb8 and its alpha-crystallin domain might act as pleiotropic prosurvival factor in the adult hippocampus.

  5. Hspb8 mRNA is constitutively expressed in specific brain structures across ontogeny; eventually these structures could be affected by the malfunction or deregulation of the Hspb8 molecule.

  6. Hsp22 represents a previously undescribed activator of both nuclear and mitochondrial functions of STAT3 (show STAT3 Antibodies), and its deletion in the context of pressure overload in vivo accelerates the transition into heart failure and increases mortality.

  7. HspB8 increases misfolded SOD1 (show SOD1 Antibodies) clearance via autophagy.

  8. Findings show that despite the ubiquitous presence of HSPB8, only motor neurons appear to be affected by the K141N and K141E mutations.

  9. H11 kinase promotes the synthesis of glycogen (show GYS1 Antibodies), an essential fuel for the stressed heart in both conditions of overload and ischemia

  10. Hsp22-mediated cardiac hypertrophy promotes an increased expression and activity, and a subcellular redistribution of the proteasome.

Heat Shock 22kDa Protein 8 (HSPB8) Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

Gene names and symbols associated with HSPB8

  • heat shock 22kDa protein 8 (hspb8) antibody
  • heat shock 22kDa protein 8 (HSPB8) antibody
  • heat shock 22kDa protein 8 (LOC100349029) antibody
  • heat shock protein, alpha-crystallin-related, b8 (hspb8) antibody
  • heat shock protein 8 (Hspb8) antibody
  • heat shock protein B8 (Hspb8) antibody
  • AU018630 antibody
  • AW413033 antibody
  • CMT2L antibody
  • Cryac antibody
  • D5Ucla4 antibody
  • DHMN2 antibody
  • E2IG1 antibody
  • fc09c11 antibody
  • H11 antibody
  • H11K antibody
  • HMN2 antibody
  • HMN2A antibody
  • HSP20-like antibody
  • Hsp22 antibody
  • MGC64408 antibody
  • wu:fc04b04 antibody
  • wu:fc09c11 antibody
  • zgc:64202 antibody

Protein level used designations for HSPB8

heat shock 22kDa protein 8 , heat shock 27kDa protein 8 , heat shock protein beta-8 , E2-induced gene 1 protein , alpha-crystallin C chain , protein kinase H11 , small stress protein-like protein HSP22 , H11 kinase , crystallin, alpha C , heat shock protein 20-like protein , heat shock protein 8

GENE ID SPECIES
379472 Xenopus laevis
416988 Gallus gallus
452295 Pan troglodytes
100174469 Pongo abelii
100349029 Oryctolagus cuniculus
791580 Danio rerio
26353 Homo sapiens
403553 Canis lupus familiaris
539524 Bos taurus
574341 Macaca mulatta
80888 Mus musculus
113906 Rattus norvegicus
Selected quality suppliers for anti-Heat Shock 22kDa Protein 8 (HSPB8) Antibodies
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