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anti-Hepatic Leukemia Factor (HLF) Antibodies

HLF encodes a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors. Additionally we are shipping HLF Proteins (6) and HLF Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HLF 29452 Q9JHS1
HLF 13819 P97481
HLF 3131 Q16534
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Top anti-HLF Antibodies at antibodies-online.com

Showing 10 out of 41 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-HLF Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Hela cell lysate WB Suggested Anti-HLF  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-Hlf AntibodyTitration: 1.0 µg/mL  Positive Control: Mouse Testis 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB HLF Antibody (C-term)  western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the HLF antibody detected the HLF protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IF, RNAi, ELISA, WB Western Blot analysis of HLF expression in transfected 293T cell line by HLF monoclonal antibody (M04), clone M2.Lane 1: HLF transfected lysate(33.2 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of monoclonal antibody to HLF on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 14 Days
$527.15
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of to HLF on HeLa cell . Western Blot analysis of HLF expression in transfected 293T cell line by HLF monoclonal antibody (M04), clone M2. Lane 1: HLF transfected lysate(33.2 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated WB Western Blot analysis of HLF expression in transfected 293T cell line by HLF monoclonal antibody (M01), clone 1F12-1C4. Lane 1: HLF transfected lysate(33.2 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

HLF Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)


Mouse (Murine)


Human ,
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,
, , , , ,

Top referenced anti-HLF Antibodies

  1. Human Monoclonal HLF Primary Antibody for IF, RNAi - ABIN561276 : Murakami, Higashi, Matsunaga, Koyanagi, Ohdo: Circadian clock-controlled intestinal expression of the multidrug-resistance gene mdr1a in mice. in Gastroenterology 2008 (PubMed)

More Antibodies against HLF Interaction Partners

Mouse (Murine) Hepatic Leukemia Factor (HLF) interaction partners

  1. demonstrate that HIF-2alpha (show EPAS1 Antibodies) is clearly implicated in the TSP1 (show GZMA Antibodies) pulmonary regulation and provide new insights on its contribution to pulmonary arterial hypertension-driven vascular remodelling and vasoconstriction

  2. Results demonstrate that Hlf is a genetic modifier of epilepsy caused by voltage-gated sodium channel mutations and that modulation of the pyridoxine pathway can also influence phenotype severity

  3. Findings identify a reciprocal activation mechanism involving HIF-2alpha (show EPAS1 Antibodies) and the zinc-ZIP8 (show SLC39A8 Antibodies)-MTF1 (show MTF1 Antibodies) axis during osteoarthritis pathogenesis that amplifies catabolic signaling and cartilage destruction.

  4. This review emphasizes that sympathetic nervous system homeostasis is dependent on a balance between HIF-2alpha (show EPAS1 Antibodies) and HIF-1alpha (show HIF1A Antibodies).

  5. genetic analysis suggests that tubulointerstitial cellular crosstalk modulates renal EPO (show EPO Antibodies) production under conditions of epithelial HIF activation in the kidney.

  6. Chondrocytes co-cultured with HIF-2alpha (show EPAS1 Antibodies)-overexpressing fibroblast-like synoviocytes exhibited upregulation of Mmp3 (show MMP3 Antibodies) and Mmp13 (show MMP13 Antibodies), which is similar to the effects induced by interleukin (IL)-6 (show IL6 Antibodies) treatment of chondrocytes.

  7. HIF-2alpha (show EPAS1 Antibodies) inhibits high-grade soft tissue sarcoma cell growth. Loss of HIF-2alpha (show EPAS1 Antibodies) promotes sarcoma proliferation and increases calcium and mTORC1 signalling in undifferentiated pleomorphic sarcoma and dedifferentiated liposarcoma.

  8. Conditional expression of E2A (show TCF3 Antibodies)-HLF induces B-cell precursor death and myeloproliferative-like disease in knock-in mice.

  9. HIF-2alpha (show EPAS1 Antibodies)-deficient mice displayed brown adipose tissue dysregulation, associated with reduced levels of uncoupling protein 1 (UCP1 (show UCP1 Antibodies)) and a dysfunctional thermogenic response to cold exposure.

  10. Loss of Hif-2alpha (show EPAS1 Antibodies) Rescues the Hif-1alpha (show HIF1A Antibodies) Deletion Phenotype of Neonatal Respiratory Distress In Mice

Human Hepatic Leukemia Factor (HLF) interaction partners

  1. Drug response profiling of matched patient-derived xenografts revealed a distinct profile for TCF3 (show TCF3 Antibodies)-HLF (show EPAS1 Antibodies) ALL with resistance to conventional chemotherapeutics but sensitivity to glucocorticoids.

  2. ectopic expression of HLF (show EPAS1 Antibodies), an established transcription factor that cycles with circadian rhythms, can recapitulate many features associated with circadian-dependent physiological variation.

  3. both Lmo2 (show LMO2 Antibodies) and Bcl-2 (show BCL2 Antibodies) are required for the action of E2A (show TCF3 Antibodies)-HLF (show EPAS1 Antibodies) in leukemogenesis

  4. E2A (show TCF3 Antibodies)-HLF (show EPAS1 Antibodies) promotes cell survival of t(17;19)- acute lymphoblastic leukemia cells by aberrantly up-regulating LMO2 (show LMO2 Antibodies) expression

  5. Evidence pertaining to leukemogenesis by the well-characterized oncogenic fusion protein E2A (show TCF3 Antibodies)-HLF (show EPAS1 Antibodies) is reviewed and its mechanistic implications are considered.

  6. E2A-HLF induces annexin II by substituting for cytokines that activate downstream pathways of Ras

  7. The E2A (show TCF3 Antibodies)-HLF (show EPAS1 Antibodies)-mediated over-expression of ABCB1 (show ABCB1 Antibodies) may play a role in the clinical phenotype of ALLs with a t(17;19), suggesting pharmacologic modulation of ABCB1 (show ABCB1 Antibodies) activity as a rational therapeutic strategy for this chemotherapy resistant subtype of ALL.

  8. The patients with immunophenotype of Pre-B-acute lymphoblastic leukemia were found to carry: E2A (show TCF3 Antibodies)/PBX1 (show PBX1 Antibodies) and E2A (show TCF3 Antibodies)/HLF (show EPAS1 Antibodies).

  9. In childhood acute lymphoblastic leukemia and hypercalcemia, translocation was observed in E2A (show TCF3 Antibodies)-HLF (show EPAS1 Antibodies) fusion protein.

  10. Activation of the thyroid hormone receptor beta (show THRB Antibodies)/retinoid X receptor alpha (show RXRA Antibodies) heterodimer by T(3) stimulated expression of the hepatic leukemia factor, which increases HIF-1alpha (show HIF1A Antibodies) gene expression.

HLF Antigen Profile

Protein Summary

This gene encodes a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors. The encoded protein forms homodimers or heterodimers with other PAR family members and binds sequence-specific promoter elements to activate transcription. Chromosomal translocations fusing portions of this gene with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemias. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Gene names and symbols associated with HLF

  • hepatic leukemia factor (HLF) antibody
  • hepatic leukemia factor (Hlf) antibody
  • hepatic leukemia factor a (hlfa) antibody
  • Hepatic leukemia factor (Bm1_18395) antibody
  • Hepatic leukemia factor (hlf) antibody
  • endothelial PAS domain protein 1 (Epas1) antibody
  • bHLHe73 antibody
  • DKFZp469P0721 antibody
  • E230015K02Rik antibody
  • HIF-2alpha antibody
  • HIF2A antibody
  • Hlf antibody
  • HLF1 antibody
  • HRF antibody
  • MOP2 antibody
  • zgc:153035 antibody

Protein level used designations for HLF

hepatic leukemia factor , hepatic leukemia factor 1 , zhlf1 , Hepatic leukemia factor , EPAS-1 , HIF-2 alpha , HIF-2-alpha , HIF2 alpha , HIF2-alpha , endothelial PAS domain-containing protein 1 , hypoxia inducible factor 2, alpha subunit , hypoxia inducible factor 2a , hypoxia-inducible factor 2 alpha , hypoxia-inducible factor 2-alpha , HIF-1-alpha-like factor , HIF-related factor , HIF1 alpha-like factor , HIF1alpha-like factor , HLF (HIF1alpha-like factor) , Hif like protein , hypoxia inducible transcription factor 2alpha , mHLF

GENE ID SPECIES
706623 Macaca mulatta
516069 Bos taurus
100192429 Ovis aries
100171535 Pongo abelii
593063 Strongylocentrotus purpuratus
417395 Gallus gallus
455140 Pan troglodytes
768192 Danio rerio
6098588 Brugia malayi
100380463 Salmo salar
29452 Rattus norvegicus
13819 Mus musculus
3131 Homo sapiens
217082 Mus musculus
363667 Rattus norvegicus
Selected quality suppliers for anti-HLF (HLF) Antibodies
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