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anti-Histone Deacetylase 5 (HDAC5) Antibodies

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Additionally we are shipping Histone Deacetylase 5 Kits (10) and Histone Deacetylase 5 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HDAC5 10014 Q9UQL6
HDAC5 15184  
HDAC5 84580  
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Top anti-Histone Deacetylase 5 Antibodies at antibodies-online.com

Showing 10 out of 162 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), IP, WB 0.1 mg Log in to see 6 to 8 Days
$445.50
Details
Human Rabbit Un-conjugated IP, IHC, WB Western blot analysis of HDAC5 expression in Jurkat cell lysate. 100 μg Log in to see 2 to 3 Days
$325.50
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to HDAC5 on HeLa cell (antibody concentration 10 µg/mL). HDAC5 monoclonal antibody (M01), clone 4G2 Western Blot analysis of HDAC5 expression in COLO 320 HSR. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$308.00
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$357.50
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ChIP, WB HDAC5 antibody tested by Western blot. Detection of HDAC5 by Western blot. NIH/3T3 cell extract was blotted and probed with HDAC5 antibody at a 2 µg/ml dilution. 100 μg Log in to see 1 to 2 Days
$466.67
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from Jurkat cells, using HDAC5 (Phospho-Ser498) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using HDAC5 (Phospho-Ser498) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details

HDAC5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
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Mouse (Murine) ,

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Rat (Rattus) ,


Top referenced anti-Histone Deacetylase 5 Antibodies

  1. Human Monoclonal HDAC5 Primary Antibody for IF, WB - ABIN393805 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for ABIN393805

  2. Human Polyclonal HDAC5 Primary Antibody for ChIP, WB - ABIN2668266 : Basile, Mantovani, Imbriano: DNA damage promotes histone deacetylase 4 nuclear localization and repression of G2/M promoters, via p53 C-terminal lysines. in The Journal of biological chemistry 2006 (PubMed)
    Show all 4 references for ABIN2668266

  3. Human Polyclonal HDAC5 Primary Antibody for IHC (p), IP - ABIN127240 : Wang, Bertos, Vezmar, Pelletier, Crosato, Heng, Thng, Han, Yang: HDAC4, a human histone deacetylase related to yeast HDA1, is a transcriptional corepressor. in Molecular and cellular biology 1999 (PubMed)
    Show all 2 references for ABIN127240

  4. Human Polyclonal HDAC5 Primary Antibody for IHC (p), WB - ABIN196932 : Döppler, Storz, Li, Comb, Toker: A phosphorylation state-specific antibody recognizes Hsp27, a novel substrate of protein kinase D. in The Journal of biological chemistry 2005 (PubMed)
    Show all 2 references for ABIN196932

  5. Human Polyclonal HDAC5 Primary Antibody for IP, IHC - ABIN223300 : Yamaguchi, Chakraborty, Pasek, Molkentin, Meissner: Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules. in American journal of physiology. Heart and circulatory physiology 2011 (PubMed)
    Show all 2 references for ABIN223300

  6. Human Polyclonal HDAC5 Primary Antibody for IHC (p), WB - ABIN197340 : McKinsey, Zhang, Lu, Olson: Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation. in Nature 2000 (PubMed)
    Show all 2 references for ABIN197340

More Antibodies against Histone Deacetylase 5 Interaction Partners

Human Histone Deacetylase 5 (HDAC5) interaction partners

  1. HDAC5 and HDAC6 (show HDAC6 Antibodies) were highly expressed in melanoma cells but exhibited low expression levels in normal skin cells.

  2. Formononetin-combined therapy may enhance the therapeutic efficacy of doxorubicin in glioma cells by preventing EMT (show ITK Antibodies) through inhibition of HDAC5.

  3. These results suggest a strong regulatory function of HDAC5 in the pro-inflammatory response of macrophages.

  4. In erythroid cells, pull down experiments identified the presence of a novel complex formed by HDAC5, GATA1, EKLF and pERK which was instead undetectable in cells of the megakaryocytic lineage.

  5. Data reveal a novel role of HDAC5 in modulating the KLF2 (show KLF2 Antibodies) transcriptional activation and eNOS (show NOS3 Antibodies) expression.

  6. Studied phosphorylation sites within functional HDAC5 domains, including the deacetylation domain (DAC (show AADAC Antibodies), Ser755), nuclear export signal (NES (show NES Antibodies), Ser1108), and an acidic domain (AD, Ser611).

  7. mRNA and protein levels of HDAC5 were up-regulated in human hepatocellular carcinoma.

  8. HDAC5 promoted the Six1 (show SIX1 Antibodies) expression.

  9. In C2C12 myoblasts, recombinant human HDAC5 phosphorylation by PKD (show PRKD1 Antibodies) regulated the expression of diverse metabolic genes and glucose metabolism.

  10. findings show N-Myc (show MYCN Antibodies) upregulated HDAC5 expression in neuroblastoma (show ARHGEF16 Antibodies) cells; HDAC5 repressed NEDD4 (show NEDD4 Antibodies) gene expression,increased Aurora A (show AURKA Antibodies) gene expression and consequently upregulated N-Myc protein (show MYCN Antibodies) expression;data identify HDAC5 as a novel co-factor in N-Myc (show MYCN Antibodies) oncogenesis

Mouse (Murine) Histone Deacetylase 5 (HDAC5) interaction partners

  1. It protects neurons from toxicity of prion (show PRNP Antibodies) peptide, and that this protection occurs at through the regulation of the PI3k-Akt (show AKT1 Antibodies)-mTOR (show FRAP1 Antibodies) axis.

  2. mass spectrometry-based quantitative comparison of acetylated peptides from wild-type vs HDAC6 (show HDAC6 Antibodies) knockout mice allowed to identify six new deacetylation sites possibly mediated by HDAC6 (show HDAC6 Antibodies).

  3. We therefore tested that reducing HDAC6 (show HDAC6 Antibodies) levels by genetic manipulation would attenuate early cognitive and behavioral deficits in R6/1 mice

  4. HDAC6 plays an important role in the function of CMA pathway under the HI stress induced by SCI and it may be a potential therapeutic target in acute SCI model.

  5. inhibition of HDAC5 differentially regulates ghrelin (show GHRL Antibodies) and NUCB2/ nesfatin-1 (show NUCB2 Antibodies) expression by enhancing the acetylation and phosphorylation of Raptor (show RPTOR Antibodies), which subsequently suppress mTORC1 signaling

  6. Results suggest a role for Hdac5 and Sirt2 (show SIRT2 Antibodies) in neuronal adaptations induced by chronic stress and antidepressant treatment and highlight the therapeutic potential of these targets in the treatment of depression

  7. loss of HDAC5 weakens Treg suppressive function and iTreg formation, as well as IFN-gamma (show IFNG Antibodies) production in CD8 (show CD8A Antibodies)+ T cells. Mice lacking HDAC5 do not develop spontaneous illness and do not have enhanced anti-tumor immunity.

  8. functional loss or suppression of the tumor suppressor HDAC6 (show HDAC6 Antibodies) is caused by induction of miR (show MLXIP Antibodies)-221 through coordinated JNK/c-Jun- and NF-kappaB (show NFKB1 Antibodies)-signaling pathways during liver tumorigenesis

  9. Hyperacetylation of Hsp90 (show HSP90 Antibodies) is a predictor and causal molecular determinant of stress resilience in mice. Brain-penetrant histone deacetylase 6 (show HDAC6 Antibodies) inhibitors increase Hsp90 (show HSP90 Antibodies) acetylation and modulate GR chaperone dynamics.

  10. Soluble beta-amyloid disrupts actin and microtubule dynamics via activation of RhoA (show RHOA Antibodies) and inhibition of histone deacetylase 6 (show HDAC6 Antibodies) in cultured hippocampal neurons.

Cow (Bovine) Histone Deacetylase 5 (HDAC5) interaction partners

  1. Protein kinase D-HDAC5 pathway plays an important role in VEGF regulation of gene transcription and angiogenesis

Arabidopsis thaliana Histone Deacetylase 5 (HDAC5) interaction partners

  1. Regulation of flowering time by the histone deacetylase HDA5

Histone Deacetylase 5 (HDAC5) Antigen Profile

Protein Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with HDAC5

  • histone deacetylase 5 (HDAC5) antibody
  • histone deacetylase 5 (Hdac5) antibody
  • histone deacetylase 5 (HDA05) antibody
  • histone deacetylase 6 (Hdac6) antibody
  • AI426555 antibody
  • ATHDA5 antibody
  • DKFZp459O115 antibody
  • HD5 antibody
  • Hd6 antibody
  • HDA5 antibody
  • Hdac4 antibody
  • Hdac5 antibody
  • histone deacetylase 5 antibody
  • MAF19.7 antibody
  • MAF19_7 antibody
  • mHDA1 antibody
  • mHDA2 antibody
  • mKIAA0600 antibody
  • NY-CO-9 antibody
  • Sfc6 antibody

Protein level used designations for HDAC5

histone deacetylase 5 , antigen NY-CO-9 , HD5 , histone deacetylase 4 , histone deacetylase mHDA1 , histone deacetylase mHDA2 , scurfy candidate 6

GENE ID SPECIES
100172968 Pongo abelii
10014 Homo sapiens
15184 Mus musculus
84580 Rattus norvegicus
490941 Canis lupus familiaris
504242 Bos taurus
100458256 Pongo abelii
100689350 Cricetulus griseus
836227 Arabidopsis thaliana
15185 Mus musculus
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