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anti-Hypocretin (Orexin) Receptor 1 (HCRTR1) Antibodies

The protein encoded by HCRTR1 is a G-protein coupled receptor involved in the regulation of feeding behavior. Additionally we are shipping Hypocretin (Orexin) Receptor 1 Kits (10) and Hypocretin (Orexin) Receptor 1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HCRTR1 3061 O43613
HCRTR1 230777 P58307
HCRTR1 25593 P56718
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Top anti-Hypocretin (Orexin) Receptor 1 Antibodies at antibodies-online.com

Showing 10 out of 80 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of Orexin receptor type 1 Antibody (Center) in N... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, ELISA Immunofluorescence analysis of MCF7 cells, using HCRTR1 Antibody. The ... 100 μg Log in to see 2 to 3 Days
$275.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from RAW264.7 cells, using HCRTR1 An... 100 μg Log in to see 2 to 3 Days
$275.00
Details
Dog Goat Un-conjugated EIA, WB AP31067PU-N HCRTR1 antibody staining of Human Brain lysate at 0.1 µg/m... 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Immunohistochemistry with Orexin Receptor polyclonal antibody 0.1 mg Log in to see 6 to 8 Days
$313.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB HCRTR1 Antibody (Center)  western blot analysis in NCI-H292 cell line ... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p) Anti-HCRTR1 / Orexin Receptor 1 antibody  ABIN1048952 IHC staining of ... 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p) Anti-HCRTR1 / Orexin Receptor 1 antibody  ABIN1048953 IHC staining of ... 50 μg Log in to see 8 to 10 Days
$451.00
Details

HCRTR1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Top referenced anti-Hypocretin (Orexin) Receptor 1 Antibodies

  1. Human Polyclonal HCRTR1 Primary Antibody for EIA, WB - ABIN953936 : Peltonen, Akerman, Bart: A role for PKD1 and PKD3 activation in modulation of calcium oscillations induced by orexin receptor 1 stimulation. in Biochimica et biophysica acta 2010 (PubMed)
    Show all 5 references for ABIN953936

  2. Human Polyclonal HCRTR1 Primary Antibody for ELISA, WB - ABIN1536076 : Sakurai, Amemiya, Ishii, Matsuzaki, Chemelli, Tanaka, Williams, Richardson, Kozlowski, Wilson, Arch, Buckingham, Haynes, Carr, Annan, McNulty, Liu, Terrett, Elshourbagy, Bergsma, Yanagisawa: Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. in Cell 1998 (PubMed)
    Show all 2 references for ABIN1536076

  3. Human Polyclonal HCRTR1 Primary Antibody for IF, ELISA - ABIN1535973 : Olafsdóttir, Rye, Scammell, Matheson, Stefánsson, Gulcher: Polymorphisms in hypocretin/orexin pathway genes and narcolepsy. in Neurology 2001 (PubMed)
    Show all 2 references for ABIN1535973

  4. Dog (Canine) Polyclonal HCRTR1 Primary Antibody for EIA, WB - ABIN783920 : Petersén, Gil, Maat-Schieman, Björkqvist, Tanila, Araújo, Smith, Popovic, Wierup, Norlén, Li, Roos, Sundler, Mulder, Brundin: Orexin loss in Huntington's disease. in Human molecular genetics 2004 (PubMed)

More Antibodies against Hypocretin (Orexin) Receptor 1 Interaction Partners

Human Hypocretin (Orexin) Receptor 1 (HCRTR1) interaction partners

  1. OX1R signaling can attenuate KOR (show OPRK1 Antibodies)-mediated reduction of cellular cAMP levels while enhancing KOR (show OPRK1 Antibodies)-mediated beta-arrestin recruitment and p38 (show CRK Antibodies) activation.

  2. OX1R and KOR (show OPRK1 Antibodies) heterodimerize, and this heterodimer associates with Galphas (show GNAS Antibodies), leading to increased protein kinase A (PKA) signaling pathway activity, including upregulation of intracellular cAMP levels.

  3. Results from homology and docking modeling show two alternative binding modes for orexin-A into orexin 1 receptor in concordance with what is known of G protein coupled receptors activation in general and the mutational data.

  4. Data suggest that interaction between the nociceptin/nociceptin (show PNOC Antibodies) receptor (show OPRL1 Antibodies) system and the orexin/orexin (show OX Antibodies) receptor system in neurons of the hypothalamus positively and negatively modulate complex and integrated responses to stress. [REVIEW]

  5. Orexin A upregulates the protein expression of OX1R and enhances the proliferation of SGC (show SGCB Antibodies)-7901 gastric cancer cells through the ERK (show EPHB2 Antibodies) signaling pathway.

  6. Orexin (show OX Antibodies) receptor binding was strongly dependent on the extracellular Ca(2 (show CA2 Antibodies)+) concentration.

  7. No significant differences were found in the distribution of either genotypic or allelic frequencies between Alzheimer's disease cases and controls in the HCRTR1 polymorphisms.

  8. Orexins modifiy orexin (show OX Antibodies) receptor gene expression and gonadotropin release from the anterior pituitary gland.

  9. DQ B1 but not HLA-DR typing, TNF-alpha (show TNF Antibodies) levels, HCRTR1 and HCRTR2 (show HCRTR2 Antibodies) were higher in narcolepsy-cataplexy/schizophrenia patients.

  10. The present data indicate that OX1R-driven apoptosis is overexpressed in androgeno-independent prostate cancer exhibiting a neuroendocrine differentiation opening a gate for novel therapies for these aggressive cancers which are incurable until now.

Mouse (Murine) Hypocretin (Orexin) Receptor 1 (HCRTR1) interaction partners

  1. Study provides pharmacological and molecular evidence indicating, respectively, a role for OXR1 (show OXR1 Antibodies) signaling in ethanol and saccharin binge-like drinking

  2. orexin (show OX Antibodies) activation of OX1R in the bone locally suppresses bone formation and enhances bone resorption by lowering osseous ghrelin (show GHRL Antibodies) expression.

  3. findings demonstrate that Hcrtr-1 modulates the reinforcing properties of cannabinoids.

  4. The transcripts for the Orx1 (show OR13H1 Antibodies) and Orx2 receptors diverged in the basolateral amygdala with Orx1 (show OR13H1 Antibodies) increasing and Orx2 decreasing in animals that were susceptible to the chronic defeat.

  5. more severe depressive behavior was associated with reduced hippocampal orexin (show OX Antibodies) expression, contrasted with increased orexin (show OX Antibodies) plus Orx1 (show OR13H1 Antibodies) receptor mRNA expression in the amygdala.

  6. data demonstrate that hypocretin (show OX Antibodies) signaling acting on Hcrtr-1 in the PVN plays a crucial role in the expression of nicotine withdrawal.

  7. Dynlt1 (show DYNLT1 Antibodies) modulates orexin (show OX Antibodies) signaling by regulating OX1R

  8. results indicate that hcrtr1 and 2 signaling oppose one another in the regulation of depression-like behaviors.

  9. These results suggest that orexin (show OX Antibodies) and its receptor may play roles in traumatic brain injury, and that OX1R is induced in neurons and microglial cells after traumatic brain injury.

  10. These data suggest that activation of the Ox1r is a necessary component of food-reinforced responding, motivation, or both in normal mice

Cow (Bovine) Hypocretin (Orexin) Receptor 1 (HCRTR1) interaction partners

  1. These data confirmed expression of orexin (show OX Antibodies) and its two receptors in the bovine adrenal gland.

  2. first evidence for the expression of oxA and ox1R in the vestibular glands of mammalian genital tract

Pig (Porcine) Hypocretin (Orexin) Receptor 1 (HCRTR1) interaction partners

  1. 39 of 41 in: Acta (show ACTA1 Antibodies) Histochem. 2014 Jan;116(1) Orexin (show OX Antibodies) 1 receptor is expressed in the seminiferous tubules of boar testis.

  2. Immunoreactivity (IR) for both orexins A and B (OXA and OXB), and cognate receptors (OX1R and OX2R (show HCRTR2 Antibodies)) were identified only in the excretory striated (show NSDHL Antibodies) ducts of the MSG while acinar cells were not immunoreactive.

  3. Data demonstrated the presence of OX1R and OX2R (show HCRTR2 Antibodies) genes and proteins in the ovary of the pig and the impact of the hormonal milieu on the expression of both receptors.

  4. expression of OX1R and Ox2R (show HCRTR2 Antibodies) in hypothalamus during oestrous cycle; evidence OX1R and OX2R (show HCRTR2 Antibodies) mRNAs and proteins occur in hypothalamic structures engaged in control of reproduction; indicate dependence of OXR expression on endocrine reproductive state

  5. findings provide the first evidence that orexin (show OX Antibodies) receptors 1 and 2 messenger RNAs and proteins occur in the pituitary of the pig and indicate the dependence of orexin (show OX Antibodies) receptor expression on the endocrine reproductive state

Hypocretin (Orexin) Receptor 1 (HCRTR1) Antigen Profile

Protein Summary

The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B.

Gene names and symbols associated with HCRTR1

  • hypocretin (orexin) receptor 1 (HCRTR1) antibody
  • orexin receptor 1 (LOC100352294) antibody
  • hypocretin (orexin) receptor 1 (Hcrtr1) antibody
  • orexin receptor 1 (LOC443167) antibody
  • orexin receptor type 1-like (LOC100855896) antibody
  • HCRTR1 antibody
  • Hctr1 antibody
  • Ox1r antibody

Protein level used designations for HCRTR1

orexin receptor 1 , hypocretin (orexin) receptor 1 , orexin receptor type 1-like , hypocretin receptor 1 , hypocretin receptor type 1 , hypocretin receptor-1 , orexin receptor type 1 , orexin receptor-1 , ox-1-R , ox1-R , ox1r , ox1R

GENE ID SPECIES
469261 Pan troglodytes
487320 Canis lupus familiaris
705914 Macaca mulatta
100056164 Equus caballus
100352294 Oryctolagus cuniculus
100412613 Callithrix jacchus
100443700 Pongo abelii
100484029 Ailuropoda melanoleuca
100587464 Nomascus leucogenys
3061 Homo sapiens
230777 Mus musculus
25593 Rattus norvegicus
282248 Bos taurus
387287 Sus scrofa
443167 Ovis aries
100855896 Canis lupus familiaris
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