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anti-Lymphocyte-Specific Protein 1 (LSP1) Antibodies

LSP1 encodes an intracellular F-actin binding protein. Additionally we are shipping LSP1 Proteins (5) and LSP1 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LSP1 16985 P19973
LSP1 4046 P33241
LSP1 361680  
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Top anti-LSP1 Antibodies at antibodies-online.com

Showing 10 out of 135 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB LSP1 Antibody (Center) (ABIN651634) western blot analysis in MCF-7 cell line lysates (35 µg/lane). This demonstrates the LSP1 antibody detected the LSP1 protein (arrow). LSP1 Antibody (Center) (ABIN651634) immunohistochemistry analysis in formalin fixed and paraffin embedded human lymph tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Goat Un-conjugated EIA, WB Antibody (0.05µg/ml) staining of Human Liver lysate (lane 1), Mouse Liver lysate (lane 2) and Rat Liver lysate (lane 3) (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Antibody (0.05µg/ml) staining of Human Peripheral Lymphocytes lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated IF, IP, IHC, WB Western blot analysis of LSP-1 on a A431 cell lysate (Human epithelial carcinoma, ATCC CRL-1555). Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the mouse anti-human LSP-1 antibody. Immunofluorescence staining of Jurkat cells (Human T-cell leukemia, ATCC TIB-152). 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-LSP1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: OVCAR-3 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated IHC (p), ELISA, WB 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB L1 human colon carcinoma lysates, L2 mouse brain lystaes probed (ABIN755647) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted and observed band size: 52kDa. Mouse thymocytes probed with Rabbit Anti-LSP1 (Ser204) Polyclonal Antibody, Unconjugated . 100 μL Log in to see 3 to 7 Days
$291.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 10 to 11 Days
$324.50
Details

LSP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,
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Top referenced anti-LSP1 Antibodies

  1. Human Monoclonal LSP1 Primary Antibody for IF, IP - ABIN968145 : Howard, Li, Torres, Guerrero, Coates: The 47-kD protein increased in neutrophil actin dysfunction with 47- and 89-kD protein abnormalities is lymphocyte-specific protein. in Blood 1994 (PubMed)
    Show all 5 references for ABIN968145

  2. Human Polyclonal LSP1 Primary Antibody for WB - ABIN2801907 : Jongstra-Bilen, Young, Chong, Jongstra: Human and mouse LSP1 genes code for highly conserved phosphoproteins. in Journal of immunology (Baltimore, Md. : 1950) 1990 (PubMed)
    Show all 4 references for ABIN2801907

  3. Human Polyclonal LSP1 Primary Antibody for FACS, IHC (p) - ABIN651634 : Odefrey, Stone, Gurrin, Byrnes, Apicella, Dite, Cawson, Giles, Treloar, English, Hopper, Southey,: Common genetic variants associated with breast cancer and mammographic density measures that predict disease. in Cancer research 2010 (PubMed)

  4. Cow (Bovine) Polyclonal LSP1 Primary Antibody for EIA, WB - ABIN615947 : Gringhuis, den Dunnen, Litjens, van der Vlist, Geijtenbeek: Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pylori. in Nature immunology 2009 (PubMed)

More Antibodies against LSP1 Interaction Partners

Mouse (Murine) Lymphocyte-Specific Protein 1 (LSP1) interaction partners

  1. the LSP1-myosin1e bimolecular complex plays a pivotal role in the regulation of actin cytoskeleton remodeling during Fc gamma receptor (show FCGR1A Antibodies)-driven phagocytosis.

  2. the importance of LSP1 Copy number variations and LSP1 insufficiency in the pathogenesis of rheumatoid arthritis, is reported.

  3. Data indicate that in lymphocyte specific 1 protein (LSP1)-deficient mice, PECAM-1 (show PECAM1 Antibodies) expression was reduced in endothelial cells, but not in neutrophils.

  4. TRAF1 (show TRAF1 Antibodies) and LSP1 cooperate downstream of 4-1BB (show TNFRSF9 Antibodies) to activate ERK (show EPHB2 Antibodies) signaling and down-modulate the levels of Bim (show BCL2L11 Antibodies) leading to enhanced T cell survival.

  5. Endothelial LSP1 participates in leukocyte adhesion in vitro, and leukocyte adhesion, through ICAM-1 (show ICAM1 Antibodies), fosters the activation of endothelial LSP1.

  6. LSP1 plays an important role in leukocyte recruitment induced by both KC and MIP-2 (show CXCL2 Antibodies).

  7. Data demonstrate that endothelial LSP1 is recruited to the cytoskeleton in inflammation and plays an important role in forming endothelial domes thereby regulating neutrophil transendothelial migration.

  8. Lsp1 negatively regulates fMLP (show FPR1 Antibodies)-induced polarization and chemotaxis of neutrophils during inflammation through its function on adhesion via specific integrins, such as Mac-1 (CD11b/CD18 (show ITGAM Antibodies)).

  9. The results show a complex function of LSP1 in regulating leukocyte recruitment to inflamed sites.

  10. MK2-regulated LSP1 phosphorylation is involved in stabilization of F-actin polarization during neutrophil chemotaxis.

Human Lymphocyte-Specific Protein 1 (LSP1) interaction partners

  1. LSP1 rs569550 and rs592373 polymorphisms are both risk factors for breast cancer.

  2. the importance of LSP1 Copy number variations and LSP1 insufficiency in the pathogenesis of rheumatoid arthritis, is reported.

  3. The breast cancer SNP LSP1 rs3817198 was associated with an increased risk of lung cancer (odds ratio: 1.10) This association was strongest for women with adenocarcinoma (P = 1.2x10(-4)).

  4. Data indicate that slit2N alters the localization and binding of Robo1 (show ROBO1 Antibodies) to WASp (show WASL Antibodies) and LSP1 in HIV-1-gp120 (show ITIH4 Antibodies)-treated immature dendritic cells (iDCs).

  5. Single nucleotide polymorphism in LSP1 is associated with breast cancer.

  6. The LSP1 rs3817198T>C polymorphism is a low-penetrant risk factor for developing breast cancer but may not be in Africans.

  7. Low-risk variants of LSP1 is associated with familial breast cancer.

  8. The LSP1 and 2q35 SNPs appear to interact multiplicatively on breast cancer risk for BRCA2 (show BRCA2 Antibodies) mutation carriers.

  9. LSP1 interacts with F-actin and the cytoskeleton through residues downstream of amino acid residue 230. The cytoskeleton binding site of mouse LSP1 maps to the 300-330 interval.

  10. Leukocyte-specific protein 1 is a cytoskeletal targeting protein for the ERK/MAP kinase (show MAPK1 Antibodies) pathway

LSP1 Antigen Profile

Protein Summary

This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with LSP1

  • lymphocyte-specific protein 1 (LSP1) antibody
  • lymphocyte-specific protein 1 (lsp1) antibody
  • lymphocyte specific 1 (Lsp1) antibody
  • lymphocyte-specific protein 1 (Lsp1) antibody
  • Lsp-1 antibody
  • LSP1 antibody
  • p50 antibody
  • pp52 antibody
  • WP34 antibody

Protein level used designations for LSP1

lymphocyte-specific protein 1 , lymphocyte-specific protein 1, isoform 3 , 52 kDa phosphoprotein , S37 protein , leukocyte specific protein 1 , leukocyte-specific protein 1 , lymphocyte-specific antigen WP34 , 47 kDa actin binding protein , 47 kDa actin-binding protein , F-actin binding and cytoskeleton associated protein , leufactin (leukocyte F-actin binding protein) , 1 BAC CH230-300K22 (Children's Hospital Oakland Research Institute) complete , lymphocyte specific 1

GENE ID SPECIES
100137571 Papio anubis
100158343 Xenopus laevis
16985 Mus musculus
4046 Homo sapiens
361680 Rattus norvegicus
611553 Canis lupus familiaris
374254 Gallus gallus
508832 Bos taurus
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