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Natriuretic Peptides B Proteins (NPPB)

NPPB is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. Additionally we are shipping Natriuretic Peptides B Antibodies (210) and Natriuretic Peptides B Kits (26) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NPPB 4879 P16860
NPPB 25105 P13205
Mouse NPPB NPPB 18158 P40753
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Top Natriuretic Peptides B Proteins at

Showing 10 out of 20 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
HOST_Synthetic Human Un-conjugated 4-20% SDS-PAGE of human BNP: 5, 10 and20 µg of human SNP Ioaded in each Iane under reducing conditions and stained with Coomassie Blue. Human BNP has a predicted MW of 3.46 kDa. 1 mg Log in to see 2 to 3 Days
HOST_Escherichia coli (E. coli) Human His tag   10 μg Log in to see 11 Days
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
Yeast Sheep His tag   1 mg Log in to see 56 to 66 Days
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
Yeast Cat His tag   1 mg Log in to see 56 to 66 Days

NPPB Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
Rat (Rattus) ,

Top referenced Natriuretic Peptides B Proteins

  1. Human NPPB Protein expressed in Escherichia coli (E. coli) - ABIN666711 : Harada, Fujita, Miyamoto, Kimura, Maruyama, Furia, Miyata, Taniguchi: Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes. in Cell 1989 (PubMed)
    Show all 2 references for ABIN666711

  2. Human NPPB Protein expressed in Wheat germ - ABIN1312892 : Shaw, Fildes, Pucha?ka, Basith, Yonan, Williams: BNP directly immunoregulates the innate immune system of cardiac transplant recipients in vitro. in Transplant immunology 2008 (PubMed)

More Proteins for Natriuretic Peptides B (NPPB) Interaction Partners

Pig (Porcine) Natriuretic Peptides B (NPPB) interaction partners

  1. CNP and BNP serve as oocyte maturation inhibitor to inhibit oocyte maturation in mammals

  2. ANP and BNP gene expression differs considerably between cardiac chambers in the first 72 hours of life in healthy piglets, resembling the transition from fetal to neonate circulation. The cardiac gene expression does not explain plasma concentrations.

  3. Up-regulation of BNP and a reduction in a ratio of sarcoplasmic reticulum calcium ATPase 2a in failing myocardium are observed in a porcine model of tachycardia.

  4. Data show that all five molecules, BNP, ICAM-1 (show ICAM1 Proteins), TNF-alpha (show TNF Proteins), VCAM-1 (show VCAM1 Proteins) and IL-6 (show IL6 Proteins), quickly and reliably signaled adverse interactions.

  5. identification and characterization of a novel alternatively spliced variant of porcine and human NPPB (show BNP Proteins) resulting from exon 2 skipping

  6. Arial natriuretic factor (ANF (show HESX1 Proteins)) and N-terminal proANF may be better suited than brain natriuretic peptide (show BNP Proteins) as markers of cardiac preload during the development and treatment of acute heart failure.

  7. Regional differences in BNP and CNP (show NPPC Proteins) expression were observed in myocardium with sustained left ventricular dyssynchronous contraction.

Human Natriuretic Peptides B (NPPB) interaction partners

  1. High plasma BNP levels and left ventricular wall motion abnormalities in the segments perfused with left anterior descending coronary artery or right coronary artery show a high risk for cardioembolic stroke in patients with old myocardial infarction.

  2. In heart failure patients with preserved ejection fraction, weight gain and an increase in BNP was significantly associated with decompensation.

  3. BNP, but not mutations in MYH7 (show MYH7 Proteins) may have a role in sudden cardiac death in children with hypertrophic cardiomyopathy

  4. Blood N-terminal pro-brain natriuretic peptide (show BNP Proteins) levels were higher in pulmonary embolism cases than the controls. Patients with right ventricular dysfunction had significantly higher NT-proBNP levels than those without the dysfunction.

  5. The available data strongly suggest that the addition of BNP to perioperative risk calculators is beneficial--{REVIEW}

  6. BNP levels are easy to determine and may represent an important marker for the determination of HAPE susceptibility.

  7. BNP, but not PCT (show UROD Proteins) or CRP (show CRP Proteins), may have a role in sepsis and can be used as a prognostic indicator

  8. In normal LVEF patients with significant aortic stenosis, BNP and left ventricular strain provide incremental (additive not duplicative) prognostic information.

  9. Combined with hydration, exogenous brain natriuretic peptide (show BNP Proteins) administration before contrast media effectively decreases contrast-induced nephropathy incidence in chronic kidney disease patients

  10. BNP levels can be used as a clinical indicator to predict short-term prognosis in ST-elevation myocardial infarction patients.

Mouse (Murine) Natriuretic Peptides B (NPPB) interaction partners

  1. P2X3 (show P2RX3 Proteins) receptors on mouse trigeminal ganglion neurons are subjected to contrasting modulation by inhibitory brain natriuretic peptide (show BNP Proteins) and facilitatory calcitonin gene-related peptide (show CALCA Proteins) that both operate via complex intracellular signaling.

  2. mouse trigeminal neurons endogenous BNP acts on NPR-A (show NPR1 Proteins) receptors to determine constitutive depression of P2X3 (show P2RX3 Proteins) receptor function. Tonic inhibition of P2X3 (show P2RX3 Proteins) receptor activity by BNP/NPR-A (show NPR1 Proteins)/PKG (show PRKG1 Proteins) pathways occurs via two distinct mechanisms: P2X3 (show P2RX3 Proteins) serine phosphorylation and receptor redistribution to non-raft membrane compartments

  3. The findings demonstrated a substantial role of mitochondrial dysfunction in mediating the downregulation of NKCC2 and ENaCalpha in obstructive kidney disease, possibly via iNOS-derived nitric oxide and BNP.

  4. Data (including data from studies in knockout mice) suggest expression of ANP (show NPPA Proteins)/BNP/GC-A (show GUCA1A Proteins) (atrial natriuretic peptide (show NPPA Proteins), brain natriuretic peptide (show BNP Proteins), and guanylyl cyclase-A (show NPR1 Proteins)) is important in embryonic neovascularization and organogenesis.

  5. Goalpha plays a role in ANF sorting during intracellular vectorial transport and with the presence of a mechanism that preserves the molar relationship between cellular ANF and BNP.

  6. The RNA-Seq demonstrates that NPPB (show BNP Proteins) which well activates natriuretic peptide receptor 1 (NPR1 (show NPR1 Proteins)), is well expressed in mouse dorsal root ganglian.

  7. a slow modulatory action by BNP on TRPV1 (show TRPV1 Proteins) and P2X3 (show P2RX3 Proteins) receptors outlining the role of this peptide as a negative regulator of trigeminal sensory neuron excitability to nociceptive stimuli

  8. Natriuretic peptides buffer renin (show REN Proteins)-dependent hypertension.

  9. BNP-NPRA (show NPR1 Proteins) signaling is involved in both itch and pain and does not function upstream of the GRP (show UCMA Proteins)-GRPR (show GRPR Proteins) dedicated neuronal pathway.

  10. Data indicate that the identified stress-responsive enhancer of Nppa (show NPPA Proteins) and Nppb (show BNP Proteins), the most common markers of heart failure, is a 650-bp fragment within 50 kb of the Nppa (show NPPA Proteins) and Nppb (show BNP Proteins) loci.

Natriuretic Peptides B (NPPB) Protein Profile

Protein Summary

This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.

Gene names and symbols associated with Natriuretic Peptides B Proteins (NPPB)

  • brain natriuretic peptide (BNP)
  • natriuretic peptide B (NPPB)
  • natriuretic peptide B (Nppb)
  • natriuretic peptide type B (Nppb)
  • AA408272 protein
  • Bnf protein
  • BNP protein
  • BNP1 protein
  • NPPB protein

Protein level used designations for Natriuretic Peptides B Proteins (NPPB)

gamma-brain natriuretic peptide , natriuretic peptides B , brain type natriuretic peptide , natriuretic peptide precursor B , natriuretic protein , brain natriuretic peptide , Brain natriuretic factor , iso-ANP , natriuretic peptide precursor type B , Gamma-brain natriuretic peptide

396844 Sus scrofa
4879 Homo sapiens
487441 Canis lupus familiaris
25105 Rattus norvegicus
508734 Bos taurus
100294642 Ovis aries
493764 Felis catus
18158 Mus musculus
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