NPPB Protein (His tag)

Catalog No. ABIN7319519

Product Details

Target: NPPB (Natriuretic Peptides B (NPPB))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This NPPB protein is labelled with His tag.

Purpose: Recombinant Human Natriuretic Peptides B/NPPB Protein (His Tag)

Sequence: His27-His134

Characteristics: Recombinant Human NPPB is produced by our E.coli expression system and the target gene encoding His27-His134 is expressed with a 6His tag at the N-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 1 mM EDTA, 1 mM DTT, 20 % Glycerol, pH 7.4.

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Target Details

Target: NPPB (Natriuretic Peptides B (NPPB))

Alternative Name: Natriuretic Peptides B/NPPB (NPPB Products)

Synonyms: BNP1 Protein, NPPB Protein, BNP Protein, Bnf Protein, AA408272 Protein, natriuretic peptide B Protein, natriuretic peptide type B Protein, NPPB Protein, Nppb Protein

Background:

Background: Human Natriuretic peptides B acts as a cardiac hormone, it is associated with many biological actions, such as diuresis, natriuresis, vasorelaxation, which inhibits the secretion of rennin and aldosterone. It acts as a paracrine antifibrotic factor in the heart. Natriuretic peptides B can help restore the body balance of salt and water, improves the heart function. Natriuretic peptides B binds and stimulates the cGMP production of the NPR1 receptor and binds the clearance receptor NPR3.

Synonym: Natriuretic Peptides B, Gamma-Brain Natriuretic Peptide, NPPB

Molecular Weight: 14.2 kDa

UniProt: P16860

Pathways: Hormone Activity