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anti-Numb Homolog (NUMB) Antibodies

The protein encoded by NUMB plays a role in the determination of cell fates during development. Additionally we are shipping NUMB Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NUMB 18222 Q9QZS3
NUMB 8650 P49757
NUMB 29419  
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Top anti-NUMB Antibodies at antibodies-online.com

Showing 10 out of 170 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB NUMB Antibody (N-term) (ABIN655396) immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Goat Un-conjugated EIA, IF, IP, WB 20 μg Log in to see 6 to 8 Days
$203.50
Details
Human Goat Un-conjugated ELISA, WB ABIN184679 staining (0.03µg/ml) of Mouse Brain lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue reacted with NUMB Antibody (N-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of NUMB Antibody (N-term) in NCI-H292 cell line lysates (35ug/lane). This demonstrates the NUMB antibody detected the NUMB protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of NUMB in mouse lung tissue lysate with NUMB antibody at (A) 0.25 and (B) 0.5 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB Anti- NUMB Picoband antibody, Western blotting All lanes: Anti NUMB  at 0.5ug/ml Lane 1: U87 Whole Cell Lysate at 40ug Lane 2: NEURO Whole Cell Lysate at 40ug Predicted bind size: 71KD Observed bind size: 71KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Mouse Un-conjugated FACS, WB HEK293T cells transfected with either RC216230 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-NUMB antibody (ABIN2453861), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NUMB (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-NUMB. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$595.83
Details
Mouse Goat Un-conjugated ICC, IF, ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated FACS, IF, WB 100 μL Log in to see 8 to 10 Days
$493.17
Details

NUMB Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-NUMB Antibodies

  1. Cow (Bovine) Polyclonal NUMB Primary Antibody for EIA, IF - ABIN782896 : Kharas, Lengner, Al-Shahrour, Bullinger, Ball, Zaidi, Morgan, Tam, Paktinat, Okabe, Gozo, Einhorn, Lane, Scholl, Fröhling, Fleming, Ebert, Gilliland, Jaenisch, Daley: Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia. in Nature medicine 2010 (PubMed)
    Show all 8 references for ABIN782896

  2. Human Polyclonal NUMB Primary Antibody for EIA, IHC (p) - ABIN953787 : Rennstam, McMichael, Berglund, Honeth, Hegardt, Rydén, Luts, Bendahl, Hedenfalk: Numb protein expression correlates with a basal-like phenotype and cancer stem cell markers in primary breast cancer. in Breast cancer research and treatment 2010 (PubMed)
    Show all 5 references for ABIN953787

  3. Human Polyclonal NUMB Primary Antibody for ELISA, WB - ABIN184679 : Zhong, Feder, Jiang, Jan, Jan: Asymmetric localization of a mammalian numb homolog during mouse cortical neurogenesis. in Neuron 1996 (PubMed)
    Show all 3 references for ABIN184679

  4. Human Polyclonal NUMB Primary Antibody for EIA, WB - ABIN783468 : Wu, Kwon, Rattis, Blum, Zhao, Ashkenazi, Jackson, Gaiano, Oliver, Reya: Imaging hematopoietic precursor division in real time. in Cell stem cell 2008 (PubMed)
    Show all 2 references for ABIN783468

  5. Human Polyclonal NUMB Primary Antibody for IHC (p), WB - ABIN655396 : Kyriazis, Wei, Vandermey, Jo, Xin, Mattson, Chan: Numb endocytic adapter proteins regulate the transport and processing of the amyloid precursor protein in an isoform-dependent manner: implications for Alzheimer disease pathogenesis. in The Journal of biological chemistry 2008 (PubMed)

More Antibodies against NUMB Interaction Partners

Mouse (Murine) Numb Homolog (NUMB) interaction partners

  1. Novel Role of Numb as A Regulator of Pro-inflammatory Cytokine Production in Macrophages in Response to Toll-like Receptor 4 (show TLR4 Antibodies).

  2. Loss of Numb induces a p53 (show TP53 Antibodies)-dependent senescence following skeletal muscle injury.

  3. Numb is a regulator for constitutive expression and dynamic transport of mGlu1 (show GRM1 Antibodies).

  4. we observed a glial reaction and an activity-dependent modification of Shh (show SHH Antibodies), Noggin (show NOG Antibodies), and Numb proteins. we found that Shh (show SHH Antibodies) and Noggin (show NOG Antibodies) could affect motor performance and that these proteins could be associated with both TDP-43 (show TARDBP Antibodies) and Numb

  5. Numb ensures the asymmetric outcome of self-renewing divisions by partitioning into the progeny that retains the stem cell identity, where it sustains high p53 (show TP53 Antibodies) activity.

  6. findings demonstrate that Nb and Nbl are intrinsic factors crucial for the renewal of CPCs in the PA2 and that the PA2 serves as a microenvironment for their expansion

  7. Numb/Numbl (show NUMBL Antibodies) control VEGF receptor (show FLT1 Antibodies) endocytosis, signaling, and recycling in endothelial cells, which promotes the angiogenic growth of blood vessels.

  8. Nuclear localization of Numb in early thymocyte precursors favors p53 (show TP53 Antibodies) nuclear stabilization, whereas pre-T-cell receptor (show PTCRA Antibodies)-dependent Numb nuclear exclusion promotes the p53 (show TP53 Antibodies) downmodulation essential for further differentiation.

  9. Numb promotes the trafficking of Cnga1 (show CNGA1 Antibodies) in rod photoreceptor cilia.

  10. The clathrin adaptor Numb regulates intestinal cholesterol absorption through dynamic interaction with NPC1L1 (show NPC1L1 Antibodies).

Human Numb Homolog (NUMB) interaction partners

  1. Dominant negative NUMB expression confers a high proliferative phenotype to chronic myeloid leukemia (show BCL11A Antibodies) cells.

  2. Alternative splicing of APP (show APP Antibodies), VEGFA (show VEGFA Antibodies) and NUMB may play an important role in pathogenesis of pancreatic ductal adenocarcinoma.

  3. Notch1 (show NOTCH1 Antibodies)/Numb/Snail (show SNAI1 Antibodies) signal pathway plays an important role in the pathogenesis of adenomyosis.

  4. Numb polymorphisms are associated with coronary artery disease among Han Chinese and Uighur Chinese in Xinjiang, China.

  5. Methylation of the Numb promoter contributed to hepatocarcinogenesis.

  6. results indicated that both rs2108552 and rs17781919 in the Numb gene were associated with total cholesterol level and density lipoprotein-cholesterol level in Chinese subjects.

  7. Report alternative splicing of NUMB in colorectal cancer.

  8. NANOG-NUMB-p53 signaling axis is an important regulatory pathway for tumor-initiating cells events in TIC self-renewal and liver tumorigenesis

  9. Alternative splicing of Numb may provide a useful prognostic biomarker in HCC (show FAM126A Antibodies) and is pharmacologically tractable

  10. The ability of RBM10v1 to regulate alternative splicing depends, at least in part, on a structural alteration within the second RNA recognition motif domain, and correlates with preferential expression of the NUMB exon 11 inclusion variant.

NUMB Antigen Profile

Protein Summary

The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-Numb Homolog (NUMB) Antibodies

  • numb gene homolog (Drosophila) (Numb) antibody
  • numb homolog (Drosophila) (NUMB) antibody
  • numb homolog (Drosophila) (Numb) antibody
  • C14orf41 antibody
  • c14_5527 antibody
  • Nb antibody
  • S171 antibody

Protein level used designations for anti-Numb Homolog (NUMB) Antibodies

protein numb homolog , h-Numb , numb gene homolog

GENE ID SPECIES
18222 Mus musculus
480381 Canis lupus familiaris
395639 Gallus gallus
8650 Homo sapiens
29419 Rattus norvegicus
512187 Bos taurus
100522019 Sus scrofa
Selected quality suppliers for anti-NUMB (NUMB) Antibodies
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